Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACGH52_RS05810 Genome accession   NZ_CP172447
Coordinates   1315153..1315818 (-) Length   221 a.a.
NCBI ID   WP_121702967.1    Uniprot ID   -
Organism   Streptomyces sp. BBFR25     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1310153..1320818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGH52_RS05785 (ACGH52_05785) cytR 1311238..1312260 (+) 1023 WP_399938021.1 LacI family DNA-binding transcriptional regulator Regulator
  ACGH52_RS05790 (ACGH52_05790) - 1312425..1313597 (+) 1173 WP_399946646.1 MFS transporter -
  ACGH52_RS05795 (ACGH52_05795) - 1313677..1314417 (+) 741 WP_121702964.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  ACGH52_RS05800 (ACGH52_05800) - 1314436..1314831 (-) 396 WP_121702965.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACGH52_RS05805 (ACGH52_05805) - 1314908..1315192 (+) 285 WP_121702966.1 DUF6332 family protein -
  ACGH52_RS05810 (ACGH52_05810) vraR 1315153..1315818 (-) 666 WP_121702967.1 response regulator transcription factor Regulator
  ACGH52_RS05815 (ACGH52_05815) - 1315850..1317079 (-) 1230 WP_076973403.1 sensor histidine kinase -
  ACGH52_RS05820 (ACGH52_05820) - 1317169..1318437 (-) 1269 WP_121702968.1 geranylgeranyl reductase family protein -
  ACGH52_RS05825 (ACGH52_05825) - 1318582..1319937 (+) 1356 WP_121702969.1 dipeptidase -
  ACGH52_RS05830 (ACGH52_05830) - 1320013..1320717 (+) 705 WP_121702970.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24055.92 Da        Isoelectric Point: 5.0405

>NTDB_id=953882 ACGH52_RS05810 WP_121702967.1 1315153..1315818(-) (vraR) [Streptomyces sp. BBFR25]
MIRVLLADDQSLVRAGFRALLDAQADIEVVAEAADGEEAVRSIRALRPDVVLMDIRMPLLDGLAATRRVTGDPGLREVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVDGDALLSPGVTRRLIAEFAARSKEPAAVGEMARLTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=953882 ACGH52_RS05810 WP_121702967.1 1315153..1315818(-) (vraR) [Streptomyces sp. BBFR25]
GTGATCCGTGTACTGCTCGCCGACGACCAGTCACTGGTCCGGGCCGGTTTCCGGGCCCTGCTGGACGCGCAGGCGGACAT
CGAGGTGGTCGCCGAGGCCGCCGACGGCGAGGAGGCGGTGCGCTCGATCCGCGCTCTGCGCCCGGACGTCGTCCTCATGG
ACATCCGCATGCCCCTGCTCGACGGCCTCGCCGCCACCCGCCGGGTCACCGGCGACCCGGGGCTGCGCGAGGTGAAGGTG
GTCATGCTCACCACCTTCGAACTCGACGAGTACGTCTTCGAGGCGATCCGTTCCGGGGCCTCCGGCTTCCTGGTCAAGGA
CACCGAACCCGAGGAACTCCTGCGCGCCGTGCGGGCGGTGGTGGACGGGGACGCGCTGCTGTCGCCGGGGGTGACGCGCC
GTTTGATCGCCGAGTTCGCGGCGCGATCCAAGGAGCCCGCGGCGGTCGGCGAGATGGCCCGGCTCACCGAGCGGGAGCGC
GAGGTGATGGCCCTGGTCGGCATCGGACTGTCCAACGAGGAGATCGCCCGCCGGCTGGTCGTCAGCCCGCTGACCGCCAA
GACCCACGTCAGCCGCACCATGGTGAAGCTGGGCGCCCGCGACCGGGCGCAACTGGTCGTGCTGGCCTACGAGTCGGGTT
TGGTGCGGCCGGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

97.285

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

36.889

100

0.376