Detailed information NTG0095382

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: QMM10_RS09240
• Genome accession: NZ_AP025938
• Coordinates: 1825434..1826444 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900701057
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1820434..1831444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM10_RS09215 (PC1044_18060)	-	1821555..1821848 (-)	294	WP_000977367.1	hypothetical protein	-
QMM10_RS09220 (PC1044_18070)	-	1822010..1822462 (+)	453	WP_000079154.1	universal stress protein	-
QMM10_RS09225 (PC1044_18080)	-	1822497..1823885 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
QMM10_RS09230 (PC1044_18090)	-	1823951..1824913 (+)	963	WP_001124777.1	asparaginase	-
QMM10_RS09235 (PC1044_18100)	-	1824942..1825370 (-)	429	WP_138008642.1	hypothetical protein	-
QMM10_RS09240 (PC1044_18110)	ccpA	1825434..1826444 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
QMM10_RS09245 (PC1044_18120)	-	1826869..1827468 (-)	600	WP_000866703.1	response regulator transcription factor	-
QMM10_RS09250 (PC1044_18130)	-	1827469..1828566 (-)	1098	WP_050204938.1	sensor histidine kinase	-
QMM10_RS09255 (PC1044_18140)	-	1828566..1829303 (-)	738	WP_000832827.1	ABC transporter permease	-
QMM10_RS09260 (PC1044_18150)	-	1829305..1830189 (-)	885	WP_000219362.1	ABC transporter ATP-binding protein	-
QMM10_RS09265 (PC1044_18160)	-	1830176..1830370 (-)	195	WP_050204940.1	hypothetical protein	-
QMM10_RS09270	-	1830367..1830573 (-)	207	Protein_1820	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=95382 QMM10_RS09240 WP_000990607.1 1825434..1826444(-) (ccpA) [Streptococcus pneumoniae strain PZ900701057]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=95382 QMM10_RS09240 WP_000990607.1 1825434..1826444(-) (ccpA) [Streptococcus pneumoniae strain PZ900701057]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568