Detailed information
Bioinformatically predicted
Overview
| Name | comM | Type | Regulator |
| Locus tag | QML92_RS08630 | Genome accession | NZ_AP025937 |
| Coordinates | 1704167..1704787 (-) | Length | 206 a.a. |
| NCBI ID | WP_000839909.1 | Uniprot ID | A0A098Z2X2 |
| Organism | Streptococcus pneumoniae strain PZ900700792 | ||
| Function | fratricide immunity (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1692610..1733692 | 1704167..1704787 | within | 0 |
Gene organization within MGE regions
Location: 1692610..1733692
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QML92_RS08560 (PC0780_16860) | - | 1692907..1693458 (-) | 552 | WP_001111255.1 | hypothetical protein | - |
| QML92_RS08565 (PC0780_16870) | - | 1693448..1693645 (-) | 198 | WP_000890144.1 | hypothetical protein | - |
| QML92_RS08570 (PC0780_16880) | - | 1693649..1694443 (-) | 795 | WP_001101210.1 | hypothetical protein | - |
| QML92_RS08575 (PC0780_16890) | - | 1694851..1695276 (-) | 426 | WP_000204065.1 | hypothetical protein | - |
| QML92_RS08580 (PC0780_16900) | - | 1695405..1695764 (-) | 360 | WP_000749822.1 | hypothetical protein | - |
| QML92_RS08585 (PC0780_16910) | - | 1695810..1696016 (-) | 207 | WP_000366091.1 | hypothetical protein | - |
| QML92_RS08590 (PC0780_16920) | - | 1696003..1696176 (-) | 174 | WP_000289349.1 | helix-turn-helix transcriptional regulator | - |
| QML92_RS08595 (PC0780_16930) | lytA | 1696535..1697491 (-) | 957 | WP_000405235.1 | N-acetylmuramoyl-L-alanine amidase LytA | - |
| QML92_RS08600 (PC0780_16940) | - | 1697867..1699237 (-) | 1371 | WP_001036271.1 | MATE family efflux transporter | - |
| QML92_RS08605 (PC0780_16950) | recA | 1699544..1700710 (-) | 1167 | WP_001085462.1 | recombinase RecA | Machinery gene |
| QML92_RS08610 (PC0780_16960) | cinA | 1700765..1702021 (-) | 1257 | WP_000642706.1 | competence/damage-inducible protein A | Machinery gene |
| QML92_RS08615 (PC0780_16970) | - | 1702106..1703122 (-) | 1017 | WP_000239278.1 | LCP family protein | - |
| QML92_RS08620 (PC0780_16980) | - | 1703130..1703648 (-) | 519 | WP_000455536.1 | GNAT family N-acetyltransferase | - |
| QML92_RS08625 (PC0780_16990) | tsaE | 1703638..1704081 (-) | 444 | WP_000288230.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE | - |
| QML92_RS08630 (PC0780_17000) | comM | 1704167..1704787 (-) | 621 | WP_000839909.1 | hypothetical protein | Regulator |
| QML92_RS08635 (PC0780_17010) | - | 1705093..1705956 (-) | 864 | WP_001093609.1 | helix-turn-helix transcriptional regulator | - |
| QML92_RS08640 (PC0780_17020) | - | 1706148..1706318 (+) | 171 | WP_001227863.1 | PhrA family quorum-sensing system peptide | - |
| QML92_RS08645 (PC0780_17030) | - | 1706720..1707034 (+) | 315 | WP_000420682.1 | YdcP family protein | - |
| QML92_RS08650 (PC0780_17040) | - | 1707050..1707436 (+) | 387 | WP_000985015.1 | YdcP family protein | - |
| QML92_RS08655 (PC0780_17050) | - | 1707465..1708850 (+) | 1386 | WP_000813488.1 | FtsK/SpoIIIE domain-containing protein | - |
| QML92_RS08660 | - | 1708853..1709005 (+) | 153 | WP_000879507.1 | hypothetical protein | - |
| QML92_RS08665 (PC0780_17060) | mobT | 1709028..1710233 (+) | 1206 | WP_000398284.1 | MobT family relaxase | - |
| QML92_RS08670 (PC0780_17070) | - | 1710276..1710497 (+) | 222 | WP_001009056.1 | hypothetical protein | - |
| QML92_RS08675 (PC0780_17080) | - | 1710614..1711111 (+) | 498 | WP_000342539.1 | antirestriction protein ArdA | - |
| QML92_RS08680 (PC0780_17090) | - | 1711200..1711592 (+) | 393 | WP_000723888.1 | conjugal transfer protein | - |
| QML92_RS08685 (PC0780_17100) | - | 1711576..1714023 (+) | 2448 | WP_000331160.1 | ATP-binding protein | - |
| QML92_RS08690 (PC0780_17110) | - | 1714026..1716203 (+) | 2178 | WP_001814875.1 | membrane protein | - |
| QML92_RS08695 (PC0780_17120) | - | 1716200..1717201 (+) | 1002 | WP_000769868.1 | bifunctional lysozyme/C40 family peptidase | - |
| QML92_RS08700 (PC0780_17130) | - | 1717198..1718130 (+) | 933 | WP_001224318.1 | conjugal transfer protein | - |
| QML92_RS08705 | - | 1718375..1718491 (+) | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| QML92_RS08710 (PC0780_17140) | tet(M) | 1718507..1720426 (+) | 1920 | WP_000691729.1 | tetracycline resistance ribosomal protection protein Tet(M) | - |
| QML92_RS08715 (PC0780_17150) | - | 1720790..1721035 (+) | 246 | WP_001813542.1 | hypothetical protein | - |
| QML92_RS08720 (PC0780_17160) | - | 1721032..1721367 (+) | 336 | WP_000806926.1 | hypothetical protein | - |
| QML92_RS08725 (PC0780_17170) | - | 1721380..1721748 (+) | 369 | WP_000567222.1 | hypothetical protein | - |
| QML92_RS08730 (PC0780_17180) | - | 1721735..1722034 (+) | 300 | WP_001072467.1 | DUF5960 family protein | - |
| QML92_RS08735 (PC0780_17190) | msr(D) | 1722152..1723615 (-) | 1464 | WP_000420313.1 | ABC-F type ribosomal protection protein Msr(D) | - |
| QML92_RS08740 (PC0780_17200) | mef(A) | 1723735..1724952 (-) | 1218 | WP_000417519.1 | macrolide efflux MFS transporter Mef(A) | - |
| QML92_RS08745 (PC0780_17210) | - | 1725338..1725508 (-) | 171 | WP_000873143.1 | hypothetical protein | - |
| QML92_RS08750 | - | 1726030..1726221 (+) | 192 | WP_001860868.1 | cysteine-rich KTR domain-containing protein | - |
| QML92_RS08755 (PC0780_17220) | - | 1726281..1726634 (-) | 354 | WP_001227347.1 | helix-turn-helix transcriptional regulator | - |
| QML92_RS08760 (PC0780_17230) | - | 1727139..1727561 (+) | 423 | WP_000804885.1 | sigma-70 family RNA polymerase sigma factor | - |
| QML92_RS08765 (PC0780_17240) | - | 1727558..1727788 (+) | 231 | WP_000857133.1 | helix-turn-helix domain-containing protein | - |
| QML92_RS08770 | - | 1728014..1728265 (-) | 252 | WP_001845478.1 | hypothetical protein | - |
| QML92_RS08775 (PC0780_17250) | - | 1728249..1728452 (+) | 204 | WP_000814511.1 | excisionase | - |
| QML92_RS08780 (PC0780_17260) | - | 1728534..1729751 (+) | 1218 | WP_001291561.1 | tyrosine-type recombinase/integrase | - |
| QML92_RS08785 (PC0780_17270) | - | 1730642..1732657 (+) | 2016 | WP_000732395.1 | DUF1430 domain-containing protein | - |
| QML92_RS08790 (PC0780_17280) | - | 1732659..1733291 (+) | 633 | WP_000571425.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 206 a.a. Molecular weight: 23540.66 Da Isoelectric Point: 10.1254
>NTDB_id=95301 QML92_RS08630 WP_000839909.1 1704167..1704787(-) (comM) [Streptococcus pneumoniae strain PZ900700792]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
Nucleotide
Download Length: 621 bp
>NTDB_id=95301 QML92_RS08630 WP_000839909.1 1704167..1704787(-) (comM) [Streptococcus pneumoniae strain PZ900700792]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comM | Streptococcus pneumoniae D39 |
99.515 |
100 |
0.995 |
| comM | Streptococcus pneumoniae R6 |
99.515 |
100 |
0.995 |
| comM | Streptococcus pneumoniae TIGR4 |
99.515 |
100 |
0.995 |
| comM | Streptococcus mitis NCTC 12261 |
38.462 |
94.66 |
0.364 |
| comM | Streptococcus mitis SK321 |
38.462 |
94.66 |
0.364 |