Detailed information NTG0095285

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: AAA985_RS10070
• Genome accession: NZ_AP028603
• Coordinates: 1921058..1921957 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904870.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Pne2
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1916058..1926957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA985_RS10045 (TKY181970_19730)	rsmA	1916388..1917260 (-)	873	WP_001216877.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
AAA985_RS10050 (TKY181970_19740)	-	1917391..1917699 (-)	309	WP_000333257.1	hypothetical protein	-
AAA985_RS10055 (TKY181970_19750)	-	1917692..1918333 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
AAA985_RS10060 (TKY181970_19760)	-	1918335..1920365 (-)	2031	WP_000825278.1	bacteriocin-associated integral membrane family protein	-
AAA985_RS10065 (TKY181970_19770)	-	1920442..1920738 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
AAA985_RS10070 (TKY181970_19780)	comR	1921058..1921957 (-)	900	WP_000904870.1	helix-turn-helix transcriptional regulator	Regulator
AAA985_RS10075 (TKY181970_19790)	rnmV	1922029..1922589 (-)	561	WP_000660015.1	ribonuclease M5	-
AAA985_RS10080 (TKY181970_19800)	-	1922589..1923362 (-)	774	WP_000575621.1	TatD family hydrolase	-
AAA985_RS10085 (TKY181970_19810)	-	1923658..1924356 (-)	699	WP_232036507.1	DUF1542 domain-containing protein	-
AAA985_RS10090 (TKY181970_19820)	rpmH	1924595..1924729 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
AAA985_RS10095 (TKY181970_19830)	-	1924874..1926088 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
AAA985_RS10100	-	1926244..1926537 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35351.12 Da
• Isoelectric Point: 4.8336

>NTDB_id=95285 AAA985_RS10070 WP_000904870.1 1921058..1921957(-) (comR) [Streptococcus pneumoniae strain Pne2]
MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=95285 AAA985_RS10070 WP_000904870.1 1921058..1921957(-) (comR) [Streptococcus pneumoniae strain Pne2]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAGTTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.242	99.666	0.361