Detailed information NTG0951469

Bioinformatically predicted

Overview

• Name: comP
• Type: Regulator
• Locus tag: WHO18_RS17245
• Genome accession: NZ_CP148128
• Coordinates: 3253118..3255427 (-)
• Length: 769 a.a.
• NCBI ID: WP_003242894.1
• Uniprot ID: Q99027
• Organism: Bacillus subtilis isolate FELIX_MS620
• Function: phosphorylation of ComA (predicted from homology) Competence regulation

Genomic Context

Location: 3248118..3260427

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WHO18_RS17205	mrpB	3248585..3249016 (+)	432	WP_003228819.1	Na(+)/H(+) antiporter subunit B	-
WHO18_RS17210	mrpC	3249016..3249357 (+)	342	WP_003220730.1	Na(+)/H(+) antiporter subunit C	-
WHO18_RS17215	mrpD	3249350..3250831 (+)	1482	WP_003244432.1	Na+/H+ antiporter subunit D	-
WHO18_RS17220	mrpE	3250837..3251313 (+)	477	WP_003244015.1	Na+/H+ antiporter subunit E	-
WHO18_RS17225	mrpF	3251313..3251597 (+)	285	WP_003228814.1	Na(+)/H(+) antiporter subunit F1	-
WHO18_RS17230	mnhG	3251581..3251955 (+)	375	WP_003244302.1	monovalent cation/H(+) antiporter subunit G	-
WHO18_RS17235	yuxO	3251994..3252374 (-)	381	WP_003228810.1	hotdog fold thioesterase	-
WHO18_RS17240	comA	3252393..3253037 (-)	645	WP_003220716.1	two-component system response regulator ComA	Regulator
WHO18_RS17245	comP	3253118..3255427 (-)	2310	WP_003242894.1	two-component system sensor histidine kinase ComP	Regulator
WHO18_RS17250	comX	3255442..3255609 (-)	168	WP_003242801.1	competence pheromone ComX	Regulator
WHO18_RS17255	comQ	3255597..3256496 (-)	900	WP_003243039.1	ComX modifying isoprenyl transferase ComQ	Regulator
WHO18_RS17260	degQ	3256681..3256821 (-)	141	WP_003220708.1	degradation enzyme regulation protein DegQ	Regulator
WHO18_RS17265	-	3257043..3257168 (+)	126	WP_003228793.1	hypothetical protein	-
WHO18_RS17270	-	3257282..3257650 (+)	369	WP_003243784.1	hypothetical protein	-
WHO18_RS17275	pdeH	3257626..3258855 (-)	1230	WP_003243525.1	cyclic di-GMP phosphodiesterase	-

Sequence

Protein

• Length: 769 a.a.
• Molecular weight: 89308.77 Da
• Isoelectric Point: 8.2618

>NTDB_id=951469 WHO18_RS17245 WP_003242894.1 3253118..3255427(-) (comP) [Bacillus subtilis isolate FELIX_MS620]
MKNLIKKFTIAVIVLSILYISYTTYISMNGIIIGTKIHKNDKSQFMIEEISESSYGQFVGLRQGDIILKINKEKPSDKHL
KWGYLSHINSLDILRSGKKIHLKDFDLVTLNRPYSFFLFVLPLFFYFLSIICIFYILKVNKKRRSFAAYILILLLLDISI
AYISAGGPFRGHIINRYINLFTFISSPILYLQFIQRYLGEIGKTFLNRISFLYIIPIFNLGIEFFQDYLQVDIDFLATLN
LVSFATLTLFSFSAIYLHLNKYKYAEHSFILKLLILTNTLSFAPFLIFFVLPIIFTGNYIFPALASASLLVLIPFGLVYQ
FVANKMFDIEFILGRMRYYALLAMIPTLLIVGALVLFDVMDIQMNPVRQTVFFFVVMFAVFYFKEVMDFKFRLKRFSEKF
NYQDSIFKYTQLMRGVTSLQQVFKELKNTILDVLLVSKAYTFEVTPDHKVIFLDKHEVGPDWNFYQEEFENVTSEIGKII
EVNQGFLMKVGERGGSSYVLLCLSNINTPRLTRDEISWLKTLSFYTSVSMENVLHIEELMEHLKDLKQEGTNPIWLKKLM
FAIEEKQRSGLARDLHDSVLQDLISLKRQCELFLGDFKKDDNPCREEVQDKLVQMNEQMSDVISMTRETCHELRPQLLYD
LGLVKALSKLVAQQQERVPFHIRLNTGRFTASLDLDSQLNLYRIIQEFLSNAVKHSQATDVLIMLISIQNKIVLHYEDDG
VGFDQEKNTEHSMSMGLSGIKERVRALDGRLRIETSEGKGFKADIEIEL

Nucleotide

• Length: 2310 bp

>NTDB_id=951469 WHO18_RS17245 WP_003242894.1 3253118..3255427(-) (comP) [Bacillus subtilis isolate FELIX_MS620]
TTGAAGAACTTAATAAAAAAATTCACAATAGCTGTAATTGTTTTGAGTATCCTTTATATAAGCTATACAACTTATATCAG
TATGAATGGAATTATTATTGGGACTAAGATTCATAAAAATGATAAAAGTCAATTTATGATAGAAGAAATATCGGAATCTT
CATATGGACAATTTGTTGGTCTGAGACAGGGAGACATCATATTAAAAATTAATAAAGAAAAACCTTCAGACAAACATTTG
AAATGGGGATATTTGAGTCATATTAACAGTCTGGATATTTTGAGAAGTGGAAAAAAGATTCATCTCAAAGATTTTGATTT
AGTTACTCTAAATAGACCTTATAGTTTTTTTCTGTTCGTACTTCCTTTGTTTTTTTATTTTTTAAGCATAATATGTATTT
TTTATATACTTAAAGTAAATAAAAAAAGGAGATCATTTGCTGCCTATATTCTTATTCTATTGTTATTAGACATTTCGATA
GCATATATAAGTGCAGGCGGACCATTTAGAGGACATATAATCAATCGGTATATTAACTTGTTTACTTTTATATCTTCTCC
TATTCTTTATCTTCAATTTATACAAAGATACCTTGGAGAAATAGGTAAAACTTTTTTGAATAGAATTTCTTTTCTTTATA
TCATACCAATATTTAATCTTGGTATTGAGTTTTTTCAAGACTATTTACAAGTAGATATTGATTTTTTAGCAACTCTTAAT
TTGGTTTCTTTTGCAACTTTGACTCTATTTTCTTTTTCAGCGATATACTTACATCTTAATAAATATAAATATGCTGAGCA
TTCGTTTATTCTTAAATTACTAATTTTAACAAACACTCTTTCATTTGCGCCTTTTTTGATATTTTTTGTTCTTCCAATAA
TATTTACAGGTAATTATATTTTCCCGGCATTAGCTTCGGCGTCATTACTAGTACTAATTCCGTTCGGGTTAGTATACCAA
TTTGTAGCCAATAAGATGTTTGATATAGAGTTTATCTTAGGAAGAATGAGATACTATGCTCTACTTGCCATGATACCAAC
TCTTCTAATAGTTGGTGCATTAGTTCTGTTTGATGTAATGGACATCCAGATGAACCCTGTGCGTCAAACTGTATTTTTTT
TCGTTGTCATGTTCGCTGTCTTTTATTTTAAAGAGGTCATGGATTTTAAATTTCGGTTAAAACGTTTCTCCGAAAAATTC
AACTATCAGGACAGTATTTTTAAATATACTCAGCTAATGAGGGGTGTAACTTCTCTTCAACAAGTTTTTAAAGAACTGAA
AAATACTATACTGGATGTTTTGCTTGTAAGCAAAGCTTATACCTTTGAGGTTACTCCTGATCACAAAGTGATATTTTTAG
ATAAGCATGAAGTTGGACCGGACTGGAATTTTTATCAAGAGGAATTTGAAAACGTAACTTCAGAAATTGGGAAAATTATA
GAAGTCAATCAAGGCTTTCTTATGAAAGTTGGTGAACGAGGCGGTAGTTCTTATGTTCTGCTTTGTTTATCTAATATTAA
CACTCCCCGGCTAACACGTGATGAAATATCGTGGCTGAAAACACTGTCTTTTTATACAAGTGTGTCCATGGAAAATGTCC
TGCATATTGAGGAGCTCATGGAACATTTGAAGGACTTAAAACAAGAGGGAACCAACCCCATCTGGCTGAAAAAGCTAATG
TTTGCAATCGAAGAAAAACAGCGTTCAGGACTCGCCCGCGATCTCCACGATTCGGTTCTTCAGGATTTGATTTCCTTAAA
ACGCCAGTGTGAGCTGTTTTTGGGTGATTTCAAGAAGGATGATAATCCGTGCCGTGAAGAGGTGCAGGACAAGCTTGTAC
AGATGAATGAGCAGATGTCTGATGTGATTTCGATGACGAGGGAGACGTGTCATGAGCTGCGGCCGCAGCTTCTGTATGAT
CTTGGATTGGTGAAGGCGCTGTCGAAGCTGGTGGCGCAGCAGCAGGAGCGGGTTCCGTTTCATATCCGTTTAAATACCGG
GAGATTTACGGCTTCCCTTGATCTGGATTCGCAGCTGAATTTGTACCGGATCATTCAAGAGTTTCTGTCTAATGCGGTCA
AGCACTCTCAGGCGACGGATGTGCTGATTATGCTCATCAGTATTCAAAACAAAATCGTTCTTCATTATGAGGACGATGGC
GTTGGGTTTGATCAAGAAAAAAATACTGAGCATTCCATGAGCATGGGGCTTTCTGGCATTAAGGAGAGAGTCAGGGCTTT
AGATGGGCGCCTTCGGATTGAAACAAGTGAAGGAAAGGGCTTTAAGGCTGATATTGAAATCGAATTGTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (568-638)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (679-765)

3D structure

• AlphaFold DB: Q99027

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Bacillus subtilis subsp. subtilis str. 168	100	100	1