Detailed information NTG0951260

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: WHO22_RS19195
• Genome accession: NZ_CP148122
• Coordinates: 3644893..3646050 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis isolate FELIX_MS513
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3639893..3651050

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WHO22_RS19165	yvyF	3640146..3640565 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
WHO22_RS19170	comFC	3640639..3641361 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
WHO22_RS19175	comFB	3641325..3641621 (-)	297	WP_003227989.1	late competence protein ComFB	-
WHO22_RS19180	comFA	3641681..3643072 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
WHO22_RS19185	fakBA	3643178..3644023 (-)	846	WP_003244125.1	DegV family protein	-
WHO22_RS19190	degU	3644121..3644810 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
WHO22_RS19195	degS	3644893..3646050 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
WHO22_RS19200	yvyE	3646267..3646920 (+)	654	WP_003227979.1	YigZ family protein	-
WHO22_RS19205	tagV	3646920..3648095 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
WHO22_RS19210	tagO	3648168..3649244 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
WHO22_RS19215	tuaH	3649389..3650582 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=951260 WHO22_RS19195 WP_003227983.1 3644893..3646050(-) (degS) [Bacillus subtilis isolate FELIX_MS513]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=951260 WHO22_RS19195 WP_003227983.1 3644893..3646050(-) (degS) [Bacillus subtilis isolate FELIX_MS513]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1