Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHP5G_RS23065 Genome accession   NZ_CP172203
Coordinates   4736650..4737240 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain GF161     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4731650..4742240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHP5G_RS23050 (ACHP5G_23050) uhpT 4732290..4733681 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  ACHP5G_RS23055 (ACHP5G_23055) uhpC 4733819..4735138 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  ACHP5G_RS23060 (ACHP5G_23060) uhpB 4735148..4736650 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  ACHP5G_RS23065 (ACHP5G_23065) letA 4736650..4737240 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  ACHP5G_RS23070 (ACHP5G_23070) ilvN 4737315..4737605 (-) 291 WP_001181713.1 acetolactate synthase small subunit -
  ACHP5G_RS23075 (ACHP5G_23075) ilvB 4737609..4739297 (-) 1689 WP_370169177.1 acetolactate synthase large subunit -
  ACHP5G_RS23080 (ACHP5G_23080) ivbL 4739403..4739501 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  ACHP5G_RS23085 (ACHP5G_23085) tisB 4740066..4740155 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  ACHP5G_RS23090 (ACHP5G_23090) ysdE 4740418..4740492 (-) 75 WP_211180519.1 protein YsdE -
  ACHP5G_RS23095 (ACHP5G_23095) emrD 4740574..4741758 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=951167 ACHP5G_RS23065 WP_000633668.1 4736650..4737240(-) (letA) [Escherichia coli strain GF161]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=951167 ACHP5G_RS23065 WP_000633668.1 4736650..4737240(-) (letA) [Escherichia coli strain GF161]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378