Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACHP5I_RS11520 Genome accession   NZ_CP172185
Coordinates   2370260..2372092 (+) Length   610 a.a.
NCBI ID   WP_395762601.1    Uniprot ID   -
Organism   Escherichia coli strain GF60     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2365260..2377092
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHP5I_RS11485 (ACHP5I_11485) dcyD 2365487..2366473 (+) 987 WP_096989976.1 D-cysteine desulfhydrase -
  ACHP5I_RS11490 (ACHP5I_11490) tcyL 2366488..2367156 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACHP5I_RS11495 (ACHP5I_11495) tcyN 2367153..2367905 (+) 753 WP_395762600.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHP5I_RS11500 (ACHP5I_11500) sdiA 2368135..2368857 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  ACHP5I_RS11505 (ACHP5I_11505) yecF 2368924..2369148 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHP5I_RS11510 (ACHP5I_11510) yecU 2369135..2369311 (-) 177 WP_000590347.1 protein YecU -
  ACHP5I_RS11515 (ACHP5I_11515) letA 2369607..2370263 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHP5I_RS11520 (ACHP5I_11520) uvrC 2370260..2372092 (+) 1833 WP_395762601.1 excinuclease ABC subunit UvrC Machinery gene
  ACHP5I_RS11525 (ACHP5I_11525) pgsA 2372149..2372697 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHP5I_RS11545 (ACHP5I_11545) yecA 2373347..2374012 (+) 666 WP_000847882.1 UPF0149 family protein YecA -
  ACHP5I_RS11550 (ACHP5I_11550) tyrP 2374074..2375285 (-) 1212 WP_096989978.1 tyrosine transporter TyrP -
  ACHP5I_RS11555 (ACHP5I_11555) yecH 2375477..2375716 (+) 240 WP_000377224.1 YecH family metal-binding protein -
  ACHP5I_RS11560 (ACHP5I_11560) ftnA 2375754..2376251 (-) 498 WP_000917208.1 non-heme ferritin -
  ACHP5I_RS11565 (ACHP5I_11565) yecR 2376423..2376746 (-) 324 WP_096989979.1 YecR-like lipofamily protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68228.14 Da        Isoelectric Point: 9.3685

>NTDB_id=950973 ACHP5I_RS11520 WP_395762601.1 2370260..2372092(+) (uvrC) [Escherichia coli strain GF60]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDITVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLIIRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=950973 ACHP5I_RS11520 WP_395762601.1 2370260..2372092(+) (uvrC) [Escherichia coli strain GF60]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATATAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCCTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATATTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTATCCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTTGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGTAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCGGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATCGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTGACCGCGCTTGCCAGCGTATTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCCAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACGCCGGGCGATGATTACGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCTA
TCGACGACAGTAAAATCCCGGATGTGATCCTTATTGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAGAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
TGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrB/uvrC motif (UVR)

(205-237)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae R6

37.397

99.508

0.372
  uvrC Streptococcus pneumoniae D39

37.397

99.508

0.372