Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACHP5I_RS11515 Genome accession   NZ_CP172185
Coordinates   2369607..2370263 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GF60     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2364607..2375263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACHP5I_RS11485 (ACHP5I_11485) dcyD 2365487..2366473 (+) 987 WP_096989976.1 D-cysteine desulfhydrase -
  ACHP5I_RS11490 (ACHP5I_11490) tcyL 2366488..2367156 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACHP5I_RS11495 (ACHP5I_11495) tcyN 2367153..2367905 (+) 753 WP_395762600.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACHP5I_RS11500 (ACHP5I_11500) sdiA 2368135..2368857 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  ACHP5I_RS11505 (ACHP5I_11505) yecF 2368924..2369148 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACHP5I_RS11510 (ACHP5I_11510) yecU 2369135..2369311 (-) 177 WP_000590347.1 protein YecU -
  ACHP5I_RS11515 (ACHP5I_11515) letA 2369607..2370263 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACHP5I_RS11520 (ACHP5I_11520) uvrC 2370260..2372092 (+) 1833 WP_395762601.1 excinuclease ABC subunit UvrC Machinery gene
  ACHP5I_RS11525 (ACHP5I_11525) pgsA 2372149..2372697 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACHP5I_RS11545 (ACHP5I_11545) yecA 2373347..2374012 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=950972 ACHP5I_RS11515 WP_000611328.1 2369607..2370263(+) (letA) [Escherichia coli strain GF60]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=950972 ACHP5I_RS11515 WP_000611328.1 2369607..2370263(+) (letA) [Escherichia coli strain GF60]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCATCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482