Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   WGK59_RS03785 Genome accession   NZ_CP148002
Coordinates   739541..740758 (+) Length   405 a.a.
NCBI ID   WP_015701559.1    Uniprot ID   -
Organism   Haemophilus influenzae strain AR2427     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 734541..745758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WGK59_RS03765 (WGK59_03765) corC 735505..736404 (-) 900 WP_005648977.1 CNNM family magnesium/cobalt transport protein CorC -
  WGK59_RS03770 (WGK59_03770) ampD 737036..737590 (-) 555 WP_041175038.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  WGK59_RS03775 (WGK59_03775) pilA 737704..738153 (+) 450 WP_015701561.1 prepilin peptidase-dependent pilin Machinery gene
  WGK59_RS03780 (WGK59_03780) pilB 738150..739544 (+) 1395 WP_015701560.1 GspE/PulE family protein Machinery gene
  WGK59_RS03785 (WGK59_03785) pilC 739541..740758 (+) 1218 WP_015701559.1 type II secretion system F family protein Machinery gene
  WGK59_RS03790 (WGK59_03790) pilD 740755..741447 (+) 693 WP_041175037.1 prepilin peptidase Machinery gene
  WGK59_RS03795 (WGK59_03795) rho 741503..742765 (-) 1263 WP_015701557.1 transcription termination factor Rho -
  WGK59_RS03800 (WGK59_03800) metJ 743013..743330 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  WGK59_RS03805 (WGK59_03805) cueR 743344..743730 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  WGK59_RS03810 (WGK59_03810) - 743807..744013 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  WGK59_RS03815 (WGK59_03815) - 744099..744305 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  WGK59_RS03820 (WGK59_03820) - 744379..744585 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  WGK59_RS03825 (WGK59_03825) - 744659..744865 (+) 207 WP_015701556.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46048.19 Da        Isoelectric Point: 9.6104

>NTDB_id=949983 WGK59_RS03785 WP_015701559.1 739541..740758(+) (pilC) [Haemophilus influenzae strain AR2427]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISHGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGIPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=949983 WGK59_RS03785 WP_015701559.1 739541..740758(+) (pilC) [Haemophilus influenzae strain AR2427]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGGCTGCTTCAATCTATTGAATCTGGCTT
AGCATTCTCACAAGCTATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTTGTTTGTAAAAAAATAGCCACACATCGTAGCCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTAGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCTGGCATTCCGCTTAATCAAGCGCTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTTCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTGGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.975
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.973
  pilC Glaesserella parasuis strain SC1401

39

98.765

0.385