Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   WCU25_RS24205 Genome accession   NZ_CP147542
Coordinates   5201725..5203062 (+) Length   445 a.a.
NCBI ID   WP_338877629.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain GN06816     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5196725..5208062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WCU25_RS24180 (WCU25_24180) pgeF 5196868..5197596 (-) 729 WP_003102588.1 peptidoglycan editing factor PgeF -
  WCU25_RS24185 (WCU25_24185) rluD 5197593..5198555 (-) 963 WP_003094686.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  WCU25_RS24190 (WCU25_24190) - 5198701..5199726 (+) 1026 WP_003102590.1 outer membrane protein assembly factor BamD -
  WCU25_RS24195 (WCU25_24195) - 5199883..5200128 (+) 246 WP_014603563.1 PP0621 family protein -
  WCU25_RS24200 (WCU25_24200) pilS 5200118..5201710 (+) 1593 WP_003110428.1 two-component system sensor histidine kinase PilS Regulator
  WCU25_RS24205 (WCU25_24205) pilR 5201725..5203062 (+) 1338 WP_338877629.1 two-component system response regulator PilR Regulator
  WCU25_RS24210 (WCU25_24210) thiO 5203108..5204202 (-) 1095 WP_031673552.1 glycine oxidase ThiO -
  WCU25_RS24215 (WCU25_24215) - 5204337..5204846 (+) 510 WP_003102595.1 Tfp pilus assembly protein FimT/FimU -
  WCU25_RS24220 (WCU25_24220) - 5204952..5205458 (+) 507 WP_003102598.1 Tfp pilus assembly protein FimT/FimU -
  WCU25_RS24225 (WCU25_24225) pilV 5205449..5206006 (+) 558 WP_003119423.1 type 4a pilus minor pilin PilV Machinery gene
  WCU25_RS24230 (WCU25_24230) pilW 5206003..5206827 (+) 825 WP_003119422.1 type 4a pilus minor pilin PilW -
  WCU25_RS24235 (WCU25_24235) pilX 5206824..5207411 (+) 588 WP_023090846.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49750.06 Da        Isoelectric Point: 5.8638

>NTDB_id=946879 WCU25_RS24205 WP_338877629.1 5201725..5203062(+) (pilR) [Pseudomonas aeruginosa strain GN06816]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLADRI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGANQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=946879 WCU25_RS24205 WP_338877629.1 5201725..5203062(+) (pilR) [Pseudomonas aeruginosa strain GN06816]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGCAGCGGCAAGGAACTGGTGGCGCGCCTGATCCACGAGCAGGGCCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGATCGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAACCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.551

100

0.996
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.063

99.775

0.38