Detailed information NTG0944612

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: V9W58_RS18565
• Genome accession: NZ_CP146764
• Coordinates: 3697862..3699025 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain AP202
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3692862..3704025

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V9W58_RS18535 (V9W58_18535)	-	3693126..3693545 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
V9W58_RS18540 (V9W58_18540)	comFC	3693619..3694308 (-)	690	WP_201756968.1	phosphoribosyltransferase family protein	Machinery gene
V9W58_RS18545 (V9W58_18545)	-	3694314..3694598 (-)	285	WP_007407481.1	competence protein ComFB	-
V9W58_RS18550 (V9W58_18550)	comFA	3694656..3696041 (-)	1386	WP_251248169.1	DEAD/DEAH box helicase	Machinery gene
V9W58_RS18555 (V9W58_18555)	-	3696150..3696998 (-)	849	WP_136396659.1	DegV family protein	-
V9W58_RS18560 (V9W58_18560)	degU	3697096..3697785 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
V9W58_RS18565 (V9W58_18565)	degS	3697862..3699025 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
V9W58_RS18570 (V9W58_18570)	-	3699248..3699895 (+)	648	WP_061581228.1	YigZ family protein	-
V9W58_RS18575 (V9W58_18575)	-	3699900..3701120 (+)	1221	WP_061581227.1	LCP family protein	-
V9W58_RS18580 (V9W58_18580)	-	3701219..3702295 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
V9W58_RS18585 (V9W58_18585)	-	3702428..3703624 (-)	1197	WP_251248168.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=944612 V9W58_RS18565 WP_007407484.1 3697862..3699025(-) (degS) [Bacillus velezensis strain AP202]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=944612 V9W58_RS18565 WP_007407484.1 3697862..3699025(-) (degS) [Bacillus velezensis strain AP202]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGGGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGTTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTG
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951