Detailed information NTG0944535

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: V9W62_RS17195
• Genome accession: NZ_CP146763
• Coordinates: 3528447..3529610 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain AP81
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3523447..3534610

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V9W62_RS17165 (V9W62_17165)	-	3523711..3524130 (-)	420	WP_043020594.1	TIGR03826 family flagellar region protein	-
V9W62_RS17170 (V9W62_17170)	comFC	3524204..3524893 (-)	690	WP_235611321.1	phosphoribosyltransferase family protein	Machinery gene
V9W62_RS17175 (V9W62_17175)	-	3524899..3525183 (-)	285	WP_007407481.1	competence protein ComFB	-
V9W62_RS17180 (V9W62_17180)	comFA	3525241..3526626 (-)	1386	WP_043020592.1	DEAD/DEAH box helicase	Machinery gene
V9W62_RS17185 (V9W62_17185)	-	3526735..3527583 (-)	849	WP_003151387.1	DegV family protein	-
V9W62_RS17190 (V9W62_17190)	degU	3527681..3528370 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
V9W62_RS17195 (V9W62_17195)	degS	3528447..3529610 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
V9W62_RS17200 (V9W62_17200)	-	3529833..3530480 (+)	648	WP_007407485.1	YigZ family protein	-
V9W62_RS17205 (V9W62_17205)	-	3530485..3531744 (+)	1260	WP_043020591.1	LCP family protein	-
V9W62_RS17210 (V9W62_17210)	-	3531843..3532919 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
V9W62_RS17215 (V9W62_17215)	-	3533052..3534248 (-)	1197	WP_043021844.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=944535 V9W62_RS17195 WP_007407484.1 3528447..3529610(-) (degS) [Bacillus velezensis strain AP81]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=944535 V9W62_RS17195 WP_007407484.1 3528447..3529610(-) (degS) [Bacillus velezensis strain AP81]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCATGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951