Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   VP398_RS02395 Genome accession   NZ_CP146231
Coordinates   493116..493781 (-) Length   221 a.a.
NCBI ID   WP_000203219.1    Uniprot ID   A0A219CAS9
Organism   Acinetobacter baumannii strain G20AB08     
Function   regulate competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 491969..500876 493116..493781 within 0


Gene organization within MGE regions


Location: 491969..500876
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VP398_RS02395 (VP398_02395) crp 493116..493781 (-) 666 WP_000203219.1 cAMP-activated global transcriptional regulator CRP Regulator
  VP398_RS02400 (VP398_02400) - 494022..494141 (+) 120 Protein_467 hypothetical protein -
  VP398_RS02405 (VP398_02405) - 494220..494642 (+) 423 WP_001195082.1 OsmC family protein -
  VP398_RS02410 (VP398_02410) - 494782..495872 (+) 1091 WP_085940413.1 IS4-like element ISAba1 family transposase -
  VP398_RS02415 (VP398_02415) - 495892..496203 (+) 312 Protein_470 CAP domain-containing protein -
  VP398_RS02420 (VP398_02420) - 496274..496864 (-) 591 WP_002017037.1 nicotinate-nicotinamide nucleotide adenylyltransferase -
  VP398_RS02425 (VP398_02425) - 496974..497774 (+) 801 WP_000175547.1 enoyl-CoA hydratase-related protein -
  VP398_RS02430 (VP398_02430) - 497771..498088 (-) 318 WP_000916029.1 NIF3 1 -
  VP398_RS02435 (VP398_02435) - 498157..498282 (-) 126 WP_000977276.1 KGW motif small protein -
  VP398_RS02440 (VP398_02440) - 498483..499688 (-) 1206 WP_000836944.1 multidrug effflux MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24956.78 Da        Isoelectric Point: 8.1128

>NTDB_id=942229 VP398_RS02395 WP_000203219.1 493116..493781(-) (crp) [Acinetobacter baumannii strain G20AB08]
MTSNFSQLSTDALSPGQLPESVKALLKRAHINRYPKRTTIVDAGTESKSLYLILKGSVSIILREDDEREIVVAYLNPGDF
FGEMGLFEPNPQRTAEVRTRDVCEIAEISYDNFHELSKQYPDLSYAVFAQLVRRLKNTTRKMTDLAFIDVSGRIARCLID
LSSQPEAMILPNGRQIRITRQEIGRIVGCSREMVGRVLKTLEDQGMIQTDGKAILIFLCTR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=942229 VP398_RS02395 WP_000203219.1 493116..493781(-) (crp) [Acinetobacter baumannii strain G20AB08]
ATGACTTCAAATTTTTCACAACTCAGCACAGATGCTTTATCTCCGGGGCAACTACCTGAATCCGTTAAAGCATTGTTAAA
ACGTGCTCACATCAACAGATATCCAAAACGAACCACAATTGTTGATGCCGGAACAGAGTCAAAATCTTTATATTTAATTT
TAAAAGGCTCAGTTTCAATTATTTTACGTGAAGACGATGAACGTGAAATTGTTGTGGCATATTTGAATCCTGGTGACTTC
TTTGGGGAAATGGGGCTTTTCGAACCGAACCCTCAACGTACAGCTGAAGTTCGTACCCGTGATGTCTGTGAAATTGCGGA
AATTTCATATGACAACTTCCACGAACTGAGCAAACAGTATCCAGATCTCAGCTATGCCGTTTTCGCGCAACTCGTTCGTC
GTTTAAAAAATACAACTCGTAAAATGACCGATCTTGCATTTATTGATGTGTCAGGCCGTATTGCGCGTTGCTTAATCGAC
CTATCTTCACAACCAGAAGCAATGATCTTGCCGAATGGCCGTCAAATTCGTATTACTCGACAAGAGATTGGACGCATTGT
CGGGTGTTCACGAGAAATGGTTGGCCGTGTATTAAAGACCTTAGAAGATCAAGGTATGATTCAAACTGACGGTAAAGCTA
TTCTAATTTTTCTCTGTACACGATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, crp family (Crp)

(176-207)

Cyclic nucleotide-binding domain (cNMP_binding)

(33-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A219CAS9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Acinetobacter baumannii D1279779

100

98.19

0.982
  crp Vibrio cholerae strain A1552

47.317

92.76

0.439
  crp Haemophilus influenzae Rd KW20

48.705

87.33

0.425