Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   V1211_RS04710 Genome accession   NZ_CP146065
Coordinates   943753..944382 (+) Length   209 a.a.
NCBI ID   WP_037551137.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain SPS12     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 938753..949382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V1211_RS04685 (V1211_04685) - 939463..940320 (-) 858 Protein_919 SDR family oxidoreductase -
  V1211_RS04690 (V1211_04690) - 940389..941396 (-) 1008 WP_053019077.1 HoxN/HupN/NixA family nickel/cobalt transporter -
  V1211_RS04695 (V1211_04695) - 941608..941994 (+) 387 WP_037537962.1 hypothetical protein -
  V1211_RS04700 (V1211_04700) liaF 942019..942720 (+) 702 WP_011275374.1 cell wall-active antibiotics response protein LiaF -
  V1211_RS04705 (V1211_04705) vraS 942717..943763 (+) 1047 WP_037537960.1 sensor histidine kinase Regulator
  V1211_RS04710 (V1211_04710) vraR 943753..944382 (+) 630 WP_037551137.1 two-component system response regulator VraR Regulator
  V1211_RS04715 (V1211_04715) - 944445..945656 (-) 1212 WP_107612160.1 YihY/virulence factor BrkB family protein -
  V1211_RS04720 (V1211_04720) - 945857..946141 (-) 285 WP_011275378.1 YtxH domain-containing protein -
  V1211_RS04725 (V1211_04725) - 946147..946611 (-) 465 WP_037537954.1 low molecular weight protein-tyrosine-phosphatase -
  V1211_RS04730 (V1211_04730) - 946753..946962 (+) 210 WP_080290985.1 DUF1128 domain-containing protein -
  V1211_RS04735 (V1211_04735) - 946976..948223 (+) 1248 WP_107612159.1 aminopeptidase -
  V1211_RS04740 (V1211_04740) - 948256..948789 (+) 534 WP_011275382.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23591.23 Da        Isoelectric Point: 5.0058

>NTDB_id=941477 V1211_RS04710 WP_037551137.1 943753..944382(+) (vraR) [Staphylococcus haemolyticus strain SPS12]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEIVGEGESGKDAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTYNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=941477 V1211_RS04710 WP_037551137.1 943753..944382(+) (vraR) [Staphylococcus haemolyticus strain SPS12]
ATGACGATTAAAGTTTTGTTCGTTGATGACCATGAAATGGTTAGAATTGGGATATCAAGTTATCTATCAACACAATCTGA
CATTGAGATAGTTGGAGAAGGGGAATCTGGTAAAGACGCCATTGCAAAAGCTCATGAATTAAAACCTGATTTAATTCTTA
TGGATTTATTAATGGATGACATGGATGGTGTCGAAGCAACTACTCAAATCAAAAAAGATTTGCCGCATATTAAAGTTGTA
ATGTTAACTAGTTTTATTGAAGATAAAGAAGTATATAGAGCATTAGATGCTGGTGTAGATAGCTATATTTTAAAAACGAC
TAGTGCTAGTGATATAGCCGACGCAGTACGCAAAACTTATAATGGTGAATCGGTATTTGAACCTGAAGTTTTAGTTAAGA
TGCGTAACAGAATGAAGAAACGTGCAGAATTATATGAAATGCTGACTGAGCGTGAAATGGAAATTTTATTATTAATTGCA
AAAGGGTATTCAAATCAAGAAATAGCGAGTGCTTCTCATATTACAATTAAAACCGTTAAAACTCATGTAAGTAATATATT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCCGTAATTTATGCATTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.694

100

0.957
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364