Detailed information NTG0941476

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: V1211_RS04705
• Genome accession: NZ_CP146065
• Coordinates: 942717..943763 (+)
• Length: 348 a.a.
• NCBI ID: WP_037537960.1
• Uniprot ID: A0AB38PEC5
• Organism: Staphylococcus haemolyticus strain SPS12
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 937717..948763

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V1211_RS04680 (V1211_04680)	map	938601..939353 (+)	753	WP_011275369.1	type I methionyl aminopeptidase	-
V1211_RS04685 (V1211_04685)	-	939463..940320 (-)	858	Protein_919	SDR family oxidoreductase	-
V1211_RS04690 (V1211_04690)	-	940389..941396 (-)	1008	WP_053019077.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
V1211_RS04695 (V1211_04695)	-	941608..941994 (+)	387	WP_037537962.1	hypothetical protein	-
V1211_RS04700 (V1211_04700)	liaF	942019..942720 (+)	702	WP_011275374.1	cell wall-active antibiotics response protein LiaF	-
V1211_RS04705 (V1211_04705)	vraS	942717..943763 (+)	1047	WP_037537960.1	sensor histidine kinase	Regulator
V1211_RS04710 (V1211_04710)	vraR	943753..944382 (+)	630	WP_037551137.1	two-component system response regulator VraR	Regulator
V1211_RS04715 (V1211_04715)	-	944445..945656 (-)	1212	WP_107612160.1	YihY/virulence factor BrkB family protein	-
V1211_RS04720 (V1211_04720)	-	945857..946141 (-)	285	WP_011275378.1	YtxH domain-containing protein	-
V1211_RS04725 (V1211_04725)	-	946147..946611 (-)	465	WP_037537954.1	low molecular weight protein-tyrosine-phosphatase	-
V1211_RS04730 (V1211_04730)	-	946753..946962 (+)	210	WP_080290985.1	DUF1128 domain-containing protein	-
V1211_RS04735 (V1211_04735)	-	946976..948223 (+)	1248	WP_107612159.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40138.53 Da
• Isoelectric Point: 5.8508

>NTDB_id=941476 V1211_RS04705 WP_037537960.1 942717..943763(+) (vraS) [Staphylococcus haemolyticus strain SPS12]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDIYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGSKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=941476 V1211_RS04705 WP_037537960.1 942717..943763(+) (vraS) [Staphylococcus haemolyticus strain SPS12]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTATTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATAGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCG
CAAATCGAGCATGCCATTGAAGGAGAAACAGTAGGTATTAATGATCAAAACATTGAGCTCTATAACGAAACCATAGATAT
TTATCAAACATTAGTTCCGTTGAATCAAGAGTTACACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAGAATTATA
ATATGAATGATGTTAAAGTTAAGAAAATCATTGAGGATGAACGACAGAGATTAGCTCGCGAGTTACACGACTCTGTTAGT
CAACAACTTTTTGCAGCAAGCATGATGTTATCTGCAATAAAAGAAACAAAATTAGAGGCACCGCTTGATCAACAAATACC
AGTATTAGAGAAAATGGTACAGGAATCTCAACTTGAAATGCGCGCATTGTTACTTCATTTAAGACCTTTAGGACTGAAAG
ATAAATCTCTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTTAAGGTGCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCTAATGGATCTAAAGTTACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGATAATGGTAAAG
GATTCAATGTTGACGAGAAATTAGAACAAAGTTATGGATTAAAAAATATGAGGGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTTTCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCGTTAAATAAGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.643	99.713	0.914