Detailed information NTG0940710

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: V6U68_RS03245
• Genome accession: NZ_CP145866
• Coordinates: 643481..644482 (+)
• Length: 333 a.a.
• NCBI ID: WP_070576321.1
• Uniprot ID: A0A2W1INW3
• Organism: Streptococcus salivarius strain KSS9
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 638481..649482

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U68_RS03225 (V6U68_03220)	smpB	639600..640064 (+)	465	WP_002885905.1	SsrA-binding protein SmpB	-
V6U68_RS03230 (V6U68_03225)	-	640211..641617 (+)	1407	WP_410531917.1	Cof-type HAD-IIB family hydrolase	-
V6U68_RS03235 (V6U68_03230)	-	641619..641987 (+)	369	WP_002886108.1	S1 RNA-binding domain-containing protein	-
V6U68_RS03240 (V6U68_03235)	-	642084..643166 (-)	1083	WP_037597586.1	M24 family metallopeptidase	-
V6U68_RS03245 (V6U68_03240)	ccpA	643481..644482 (+)	1002	WP_070576321.1	catabolite control protein A	Regulator
V6U68_RS03250 (V6U68_03245)	-	644542..645609 (+)	1068	WP_410531919.1	MmcQ/YjbR family DNA-binding protein	-
V6U68_RS03255 (V6U68_03250)	-	645622..646737 (+)	1116	WP_410531920.1	glycerate kinase	-
V6U68_RS03260 (V6U68_03255)	-	646768..647223 (-)	456	WP_175057482.1	YueI family protein	-
V6U68_RS03265 (V6U68_03260)	eno	647429..648733 (+)	1305	WP_002886048.1	surface-displayed alpha-enolase	-
V6U68_RS03270 (V6U68_03265)	-	648883..649068 (-)	186	WP_368386834.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36702.62 Da
• Isoelectric Point: 5.4827

>NTDB_id=940710 V6U68_RS03245 WP_070576321.1 643481..644482(+) (ccpA) [Streptococcus salivarius strain KSS9]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFA
TLARGIDDIATMYKYNIVLASSDENDDHEVTVINSLFAKQVDGIIFMGYHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKVAVEDSVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKAGLEKNNLRYNEGLVFEAKYSYRDGFDLAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPITSYTRPNLSSINHPLYDLGAVSMRMLTKIMNKEELEEKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=940710 V6U68_RS03245 WP_070576321.1 643481..644482(+) (ccpA) [Streptococcus salivarius strain KSS9]
ATGAATACTGATGAAACAATCACTATTTATGACGTTGCGCGTGAGGCAGGCGTTTCGATGGCGACTGTGTCTCGTGTGGT
AAATGGAAATAAAAATGTAAAAGAAAACACCCGAAAAAAAGTGCTTGAGGTCATTGATCGTTTGGATTATCGTCCAAATG
CGGTTGCACGTGGCTTGGCGAGTAAGAAAACCACTACTGTAGGAGTTGTCATCCCAAATATTGCTAATAGTTATTTTGCT
ACTTTAGCAAGGGGGATTGATGATATTGCAACGATGTACAAGTACAATATTGTTCTTGCATCTAGTGATGAAAATGACGA
TCACGAAGTTACCGTGATTAACTCTCTATTTGCCAAACAAGTAGATGGTATCATCTTCATGGGTTACCACTTGACGGAAA
AAATTCGTGCAGAATTTTCTCGTACCCGTACTCCGATTGTCCTAGCAGGAACAGTGGACCTCGAGCACCAATTACCGAGC
GTTAATATCGACTATAAAGTTGCCGTTGAGGATTCTGTAACGCAACTTGCCAAGAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTCCGTCTAGCTGGTTATAAGGCTGGACTTGAAAAGAATAATTTGCGTT
ACAATGAAGGTCTTGTCTTCGAAGCCAAATATAGCTATAGAGATGGCTTTGATTTAGCACAACGTGTTTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGAGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGTAAATCAGTTCC
AGAAGACTTCGAAATCATCACAAGCAATGACTCACCAATTACAAGCTACACACGTCCAAACCTTTCTAGTATTAATCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATCATGAATAAGGAAGAGCTCGAAGAAAAAGATGTT
ATTCTTAATCACGGTCTTACCTTACGTCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A2W1INW3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	77.177	100	0.772
ccpA	Streptococcus pneumoniae D39	76.276	100	0.763
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	55.589	99.399	0.553