Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   V6U63_RS00875 Genome accession   NZ_CP145861
Coordinates   155728..156465 (+) Length   245 a.a.
NCBI ID   WP_002889752.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS3     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 150728..161465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U63_RS00855 (V6U63_00855) - 151018..151566 (-) 549 WP_045002105.1 VanZ family protein -
  V6U63_RS00860 (V6U63_00860) - 151907..154474 (+) 2568 WP_410535140.1 SEC10/PgrA surface exclusion domain-containing protein -
  V6U63_RS00865 (V6U63_00865) - 154784..155182 (-) 399 WP_155212187.1 hypothetical protein -
  V6U63_RS00870 (V6U63_00870) - 155380..155709 (+) 330 WP_410535142.1 LytTR family DNA-binding domain-containing protein -
  V6U63_RS00875 (V6U63_00875) comE/blpR 155728..156465 (+) 738 WP_002889752.1 response regulator transcription factor Regulator
  V6U63_RS00880 (V6U63_00880) - 156462..157799 (+) 1338 WP_155212191.1 GHKL domain-containing protein -
  V6U63_RS00885 (V6U63_00885) - 158174..158914 (+) 741 WP_155212193.1 amino acid transporter -
  V6U63_RS00890 (V6U63_00890) - 159039..159458 (+) 420 WP_155212195.1 Msa family membrane protein -
  V6U63_RS00895 (V6U63_00895) - 159451..160323 (+) 873 WP_038675187.1 ABC transporter ATP-binding protein -
  V6U63_RS00900 (V6U63_00900) - 160328..161098 (+) 771 WP_410535144.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28467.55 Da        Isoelectric Point: 7.1603

>NTDB_id=940352 V6U63_RS00875 WP_002889752.1 155728..156465(+) (comE/blpR) [Streptococcus salivarius strain KSS3]
MLNIFVLEDDFFQQTRIETAIKKCMSDNKMRYRYLEVFGKPQQLLDAIKETGNHQFFFLDIEIKGDKKRGMEIAREIREK
DPSASIVFVTTHSEFMPVTYSYRVSALDFIDKGLSDQDYQEAISSVLIHATGSVNKTIGEDSFCFKSEHSQIQVPFSDIL
YFETSPTIHKVILTTKKGHMEFYGKVSDIAKADKRLYQSHRSYVVNPENIIRIDKSNHTVFFENDESCFVSRMKLKGLVE
RITLR

Nucleotide


Download         Length: 738 bp        

>NTDB_id=940352 V6U63_RS00875 WP_002889752.1 155728..156465(+) (comE/blpR) [Streptococcus salivarius strain KSS3]
ATGTTAAATATTTTTGTTCTAGAAGATGATTTTTTTCAGCAAACTCGTATTGAGACAGCGATTAAGAAATGTATGTCTGA
TAATAAAATGAGGTATAGGTATTTAGAAGTCTTTGGTAAGCCTCAACAGTTGTTAGATGCAATTAAAGAGACAGGAAATC
ATCAATTTTTCTTTCTTGATATTGAAATTAAAGGAGATAAAAAGAGAGGAATGGAGATTGCGCGTGAAATCCGTGAAAAA
GATCCTAGTGCGTCGATTGTCTTTGTGACGACTCACTCAGAATTTATGCCAGTCACCTACAGTTACCGTGTATCTGCTTT
GGACTTTATCGACAAAGGGTTAAGTGATCAAGATTATCAGGAAGCTATTTCGTCTGTTTTGATACATGCTACTGGTAGTG
TTAATAAAACAATAGGTGAAGATTCATTTTGTTTTAAATCAGAACATTCCCAAATACAAGTTCCTTTTTCAGATATTCTT
TATTTTGAGACCTCACCTACGATTCATAAGGTAATTTTAACGACGAAGAAAGGCCATATGGAATTTTATGGTAAAGTTTC
AGATATTGCGAAGGCAGACAAAAGGCTCTACCAAAGTCATAGATCTTATGTAGTGAATCCAGAGAATATTATTCGTATTG
ACAAATCAAATCATACTGTTTTTTTTGAAAATGATGAATCTTGTTTTGTATCTCGTATGAAATTAAAAGGTTTAGTTGAG
AGGATTACTTTGAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

55.23

97.551

0.539
  comE/comE1 Streptococcus equinus JB1

50.209

97.551

0.49
  comE/comE2 Streptococcus equinus JB1

41.597

97.143

0.404