Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   V6U62_RS05515 Genome accession   NZ_CP145860
Coordinates   1224579..1225922 (-) Length   447 a.a.
NCBI ID   WP_410535408.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1219579..1230922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U62_RS05485 (V6U62_05475) - 1219756..1220142 (-) 387 WP_002884910.1 DUF1934 domain-containing protein -
  V6U62_RS05490 (V6U62_05480) - 1220225..1221091 (-) 867 WP_145516924.1 GNAT family N-acetyltransferase -
  V6U62_RS05495 (V6U62_05485) yidA 1221269..1222078 (+) 810 WP_002890845.1 sugar-phosphatase -
  V6U62_RS05500 (V6U62_05490) - 1222080..1223294 (+) 1215 WP_037611659.1 aminoacyltransferase -
  V6U62_RS05505 (V6U62_05495) - 1223346..1223705 (-) 360 WP_037611660.1 YbaN family protein -
  V6U62_RS05510 (V6U62_05500) vicX 1223764..1224576 (-) 813 WP_013990680.1 MBL fold metallo-hydrolase Regulator
  V6U62_RS05515 (V6U62_05505) vicK 1224579..1225922 (-) 1344 WP_410535408.1 cell wall metabolism sensor histidine kinase VicK Regulator
  V6U62_RS05520 (V6U62_05510) vicR 1225915..1226622 (-) 708 WP_002884978.1 response regulator YycF Regulator
  V6U62_RS05525 (V6U62_05515) - 1226907..1227674 (+) 768 WP_021145491.1 amino acid ABC transporter ATP-binding protein -
  V6U62_RS05530 (V6U62_05520) - 1227684..1228517 (+) 834 WP_410535406.1 transporter substrate-binding domain-containing protein -
  V6U62_RS05535 (V6U62_05525) - 1228535..1229233 (+) 699 WP_002886251.1 amino acid ABC transporter permease -
  V6U62_RS05540 (V6U62_05530) - 1229245..1229895 (+) 651 WP_002886253.1 amino acid ABC transporter permease -
  V6U62_RS05545 (V6U62_05535) - 1230087..1230854 (+) 768 WP_037611663.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 51058.32 Da        Isoelectric Point: 5.0731

>NTDB_id=940316 V6U62_RS05515 WP_410535408.1 1224579..1225922(-) (vicK) [Streptococcus salivarius strain KSS2]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDFETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEME

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=940316 V6U62_RS05515 WP_410535408.1 1224579..1225922(-) (vicK) [Streptococcus salivarius strain KSS2]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTTGCATATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGACGTC
TTTCGTTTGACGCATGAAAATCTGGCCCAGGAAAAAAACCGCTTATCATCAGTCCTCTCTTACATGAGTGATGGGGTTAT
TGCGACTAATCGACGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTTTGAGACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGTGAAAATCCCTATACTTATAGTGAATTGCTCTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAACTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCTGTTCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGTGAACGTCGACTTTTCGTCTCGA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGAGCTCTCGATGAA
GAGATTGCACCTAACTTCATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
GTCTCGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGAGATTACCCAGTAAACTCAATT
TGGGTAGAGATTGATACAGATAAGATGACCCAGGTCGTGGATAATATTCTTAATAATGCCATTAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCTTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAGGGTGGAACGGGTCTA
GGCTTGTCCATTGCCAAAGAGATTATTAAACAACATAAGGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
ATTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGGAGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.617

0.682
  micB Streptococcus pneumoniae Cp1015

67.667

96.868

0.655