Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACE169_RS09780 Genome accession   NZ_CP169632
Coordinates   1960386..1961042 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain L-formLTE     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1955386..1966042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE169_RS09750 (ACE169_09750) yecA 1956637..1957302 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  ACE169_RS09770 (ACE169_09770) pgsA 1957952..1958500 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACE169_RS09775 (ACE169_09775) uvrC 1958557..1960389 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACE169_RS09780 (ACE169_09780) letA 1960386..1961042 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACE169_RS09785 (ACE169_09785) - 1961184..1961255 (+) 72 Protein_1916 transcriptional regulator -
  ACE169_RS09790 (ACE169_09790) yecU 1961338..1961514 (+) 177 WP_000590347.1 protein YecU -
  ACE169_RS09795 (ACE169_09795) yecF 1961501..1961725 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACE169_RS09800 (ACE169_09800) sdiA 1961793..1962515 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  ACE169_RS09805 (ACE169_09805) tcyN 1962745..1963497 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACE169_RS09810 (ACE169_09810) tcyL 1963494..1964162 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ACE169_RS09815 (ACE169_09815) dcyD 1964177..1965163 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=939742 ACE169_RS09780 WP_000611335.1 1960386..1961042(-) (letA) [Escherichia coli strain L-formLTE]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=939742 ACE169_RS09780 WP_000611335.1 1960386..1961042(-) (letA) [Escherichia coli strain L-formLTE]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486