Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACET1G_RS10195 Genome accession   NZ_CP169013
Coordinates   2036866..2038698 (+) Length   610 a.a.
NCBI ID   WP_001283425.1    Uniprot ID   -
Organism   Escherichia coli strain UTAK-22     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2031866..2043698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACET1G_RS10155 (ACET1G_10155) dcyD 2032093..2033079 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  ACET1G_RS10160 (ACET1G_10160) tcyL 2033094..2033762 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACET1G_RS10165 (ACET1G_10165) tcyN 2033759..2034511 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACET1G_RS10170 (ACET1G_10170) sdiA 2034741..2035463 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  ACET1G_RS10175 (ACET1G_10175) yecF 2035530..2035754 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACET1G_RS10180 (ACET1G_10180) yecU 2035741..2035917 (-) 177 WP_000590347.1 protein YecU -
  ACET1G_RS10185 (ACET1G_10185) - 2036000..2036071 (-) 72 Protein_1988 transcriptional regulator -
  ACET1G_RS10190 (ACET1G_10190) letA 2036213..2036869 (+) 657 WP_000611339.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACET1G_RS10195 (ACET1G_10195) uvrC 2036866..2038698 (+) 1833 WP_001283425.1 excinuclease ABC subunit UvrC Machinery gene
  ACET1G_RS10200 (ACET1G_10200) pgsA 2038755..2039303 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACET1G_RS10220 (ACET1G_10220) - 2040298..2040579 (+) 282 WP_071529678.1 hypothetical protein -
  ACET1G_RS10225 (ACET1G_10225) - 2040769..2040909 (-) 141 WP_000078920.1 Hok/Gef family protein -
  ACET1G_RS10230 (ACET1G_10230) - 2041100..2041360 (-) 261 WP_000488108.1 ogr/Delta-like zinc finger family protein -
  ACET1G_RS10235 (ACET1G_10235) - 2041403..2042203 (-) 801 WP_244448995.1 contractile injection system protein, VgrG/Pvc8 family -
  ACET1G_RS10240 (ACET1G_10240) - 2042164..2042256 (+) 93 Protein_1996 hypothetical protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68244.14 Da        Isoelectric Point: 9.3685

>NTDB_id=938003 ACET1G_RS10195 WP_001283425.1 2036866..2038698(+) (uvrC) [Escherichia coli strain UTAK-22]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGVDRKVGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=938003 ACET1G_RS10195 WP_001283425.1 2036866..2038698(+) (uvrC) [Escherichia coli strain UTAK-22]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCACACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGTGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATACCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCTGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGCCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCACTGCTACTTGGCGTTGCCAAAGGAGTAGATCGTAAGGTTGGGCTGGA
AACACTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGCTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

Helix-hairpin-helix domain (HHH_5)

(558-609)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374