Detailed information NTG0093699

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: LLL8_RS08920
• Genome accession: NZ_AP025700
• Coordinates: 1831210..1833420 (-)
• Length: 736 a.a.
• NCBI ID: WP_251899790.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain L8
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1826210..1838420

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLL8_RS08890 (LLL8_17430)	atpA	1826252..1827754 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
LLL8_RS08895 (LLL8_17440)	-	1827941..1828468 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
LLL8_RS08900 (LLL8_17450)	atpF	1828470..1828976 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
LLL8_RS08905 (LLL8_17460)	atpB	1828991..1829704 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
LLL8_RS08910 (LLL8_17470)	-	1829749..1829964 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
LLL8_RS08915 (LLL8_17480)	-	1830149..1830925 (-)	777	WP_058220836.1	alpha/beta hydrolase family protein	-
LLL8_RS08920 (LLL8_17490)	comEC	1831210..1833420 (-)	2211	WP_251899790.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LLL8_RS08925 (LLL8_17500)	comEA	1833401..1834048 (-)	648	WP_058203544.1	ComEA family DNA-binding protein	Machinery gene
LLL8_RS08930 (LLL8_17510)	-	1834108..1835469 (-)	1362	WP_228248326.1	ABC transporter permease	-
LLL8_RS08935 (LLL8_17520)	-	1835466..1836398 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
LLL8_RS08940 (LLL8_17530)	-	1836503..1836901 (-)	399	WP_004255236.1	hypothetical protein	-
LLL8_RS08945 (LLL8_17540)	-	1837005..1837568 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84419.08 Da
• Isoelectric Point: 9.6878

>NTDB_id=93699 LLL8_RS08920 WP_251899790.1 1831210..1833420(-) (comEC) [Lactococcus lactis strain L8]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQDI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKGRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANITIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=93699 LLL8_RS08920 WP_251899790.1 1831210..1833420(-) (comEC) [Lactococcus lactis strain L8]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGGATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCGT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTGTTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAGGAA
GACAAATAATTTTTGCAGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTACGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

• Domain of unknown function (DUF4131) (DUF4131) (27-171)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.902	100	0.769
comEC/celB	Streptococcus mitis SK321	44.474	100	0.448
comEC/celB	Streptococcus mitis NCTC 12261	44.34	100	0.447
comEC/celB	Streptococcus pneumoniae TIGR4	43.607	100	0.44
comEC/celB	Streptococcus pneumoniae Rx1	43.203	100	0.436
comEC/celB	Streptococcus pneumoniae D39	43.203	100	0.436
comEC/celB	Streptococcus pneumoniae R6	43.203	100	0.436