Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   V5G03_RS08215 Genome accession   NZ_CP145077
Coordinates   1576133..1576582 (-) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria gonorrhoeae strain WHO_G_2024     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1575610..1583862 1576133..1576582 within 0


Gene organization within MGE regions


Location: 1575610..1583862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G03_RS08210 (V5G03_08220) - 1575610..1575756 (+) 147 WP_003691757.1 hypothetical protein -
  V5G03_RS08215 (V5G03_08225) comP 1576133..1576582 (-) 450 WP_002214937.1 type IV pilin protein Machinery gene
  V5G03_RS08220 (V5G03_08230) comE 1576670..1577065 (-) 396 WP_003703428.1 helix-hairpin-helix domain-containing protein Machinery gene
  V5G03_RS08225 (V5G03_08235) - 1577167..1577286 (-) 120 Protein_1605 competence protein ComE -
  V5G03_RS08255 (V5G03_08265) - 1582910..1583563 (-) 654 Protein_1606 TIGR01621 family pseudouridine synthase -
  V5G03_RS08260 (V5G03_08270) - 1583623..1583862 (-) 240 WP_229684458.1 HAD hydrolase family protein -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=936955 V5G03_RS08215 WP_002214937.1 1576133..1576582(-) (comP) [Neisseria gonorrhoeae strain WHO_G_2024]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=936955 V5G03_RS08215 WP_002214937.1 1576133..1576582(-) (comP) [Neisseria gonorrhoeae strain WHO_G_2024]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49