Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilL   Type   Machinery gene
Locus tag   V5G03_RS02690 Genome accession   NZ_CP145077
Coordinates   522629..523102 (+) Length   157 a.a.
NCBI ID   WP_172617250.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_G_2024     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 523172..561782 522629..523102 flank 70


Gene organization within MGE regions


Location: 522629..561782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G03_RS02690 (V5G03_02690) pilL 522629..523102 (+) 474 WP_172617250.1 PilX family type IV pilin Machinery gene
  V5G03_RS02695 (V5G03_02695) - 523172..523480 (-) 309 WP_010951048.1 AzlD family protein -
  V5G03_RS02700 (V5G03_02700) - 523477..524185 (-) 709 Protein_522 AzlC family ABC transporter permease -
  V5G03_RS02705 (V5G03_02705) dut 524351..524803 (+) 453 WP_047925987.1 dUTP diphosphatase -
  V5G03_RS02710 (V5G03_02710) dapC 524881..526068 (+) 1188 WP_003701073.1 succinyldiaminopimelate transaminase -
  V5G03_RS02715 (V5G03_02715) yaaA 526224..527003 (+) 780 WP_003687925.1 peroxide stress protein YaaA -
  V5G03_RS02730 (V5G03_02730) - 527533..528733 (+) 1201 Protein_526 tyrosine-type recombinase/integrase -
  V5G03_RS02735 (V5G03_02735) - 529089..529358 (-) 270 WP_003687928.1 hypothetical protein -
  V5G03_RS02740 (V5G03_02740) - 529553..530236 (-) 684 WP_003687929.1 DUF2786 domain-containing protein -
  V5G03_RS02745 (V5G03_02745) - 530550..530783 (-) 234 Protein_529 hypothetical protein -
  V5G03_RS02750 (V5G03_02750) - 530894..531109 (-) 216 WP_003691538.1 hypothetical protein -
  V5G03_RS02755 (V5G03_02755) - 531161..531652 (-) 492 WP_003691537.1 siphovirus Gp157 family protein -
  V5G03_RS02760 (V5G03_02760) - 531649..531831 (-) 183 WP_003691535.1 hypothetical protein -
  V5G03_RS02765 (V5G03_02765) - 531971..532657 (-) 687 WP_012503754.1 phage replication initiation protein, NGO0469 family -
  V5G03_RS02770 (V5G03_02770) - 532726..532887 (-) 162 WP_003693867.1 hypothetical protein -
  V5G03_RS02775 (V5G03_02775) - 532884..533159 (-) 276 WP_003703838.1 NGO1622 family putative holin -
  V5G03_RS02780 (V5G03_02780) - 533312..533644 (-) 333 WP_047919601.1 phage associated protein -
  V5G03_RS02785 (V5G03_02785) - 533785..534060 (-) 276 WP_106346843.1 hypothetical protein -
  V5G03_RS02790 (V5G03_02790) - 534057..534533 (-) 477 WP_002255718.1 hypothetical protein -
  V5G03_RS02795 (V5G03_02795) - 534566..534766 (-) 201 WP_003687954.1 hypothetical protein -
  V5G03_RS02800 (V5G03_02800) - 534964..535377 (-) 414 WP_003687963.1 hypothetical protein -
  V5G03_RS02805 (V5G03_02805) - 535374..535835 (-) 462 WP_003687965.1 helix-turn-helix domain-containing protein -
  V5G03_RS02810 (V5G03_02810) - 535852..536289 (-) 438 WP_003687967.1 hypothetical protein -
  V5G03_RS02815 (V5G03_02815) - 536404..537120 (-) 717 WP_003687969.1 LexA family transcriptional regulator -
  V5G03_RS02820 (V5G03_02820) - 537189..537425 (+) 237 WP_003687971.1 Cro/CI family transcriptional regulator -
  V5G03_RS02825 (V5G03_02825) - 537505..537660 (+) 156 WP_047923772.1 hypothetical protein -
  V5G03_RS02830 (V5G03_02830) - 537637..537825 (-) 189 WP_003698903.1 hypothetical protein -
  V5G03_RS02835 (V5G03_02835) - 537999..538226 (+) 228 WP_003698261.1 helix-turn-helix domain-containing protein -
  V5G03_RS02840 (V5G03_02840) - 538344..539408 (+) 1065 WP_003693470.1 hypothetical protein -
  V5G03_RS02845 (V5G03_02845) - 539405..540766 (+) 1362 WP_003689132.1 DnaB-like helicase C-terminal domain-containing protein -
  V5G03_RS02850 (V5G03_02850) - 540783..541013 (+) 231 WP_012503490.1 hypothetical protein -
  V5G03_RS02855 (V5G03_02855) - 541104..541598 (+) 495 WP_003691434.1 DUF3310 domain-containing protein -
  V5G03_RS02860 (V5G03_02860) - 541775..541924 (+) 150 WP_003689110.1 hypothetical protein -
  V5G03_RS02865 (V5G03_02865) - 541953..542234 (+) 282 WP_003689109.1 hypothetical protein -
  V5G03_RS02870 (V5G03_02870) - 542225..542662 (+) 438 WP_047918627.1 RusA family crossover junction endodeoxyribonuclease -
  V5G03_RS02875 (V5G03_02875) - 542655..542960 (+) 306 WP_003687981.1 nuclease domain-containing protein -
  V5G03_RS02880 (V5G03_02880) - 542957..543340 (+) 384 WP_003690918.1 recombination protein NinB -
  V5G03_RS02885 (V5G03_02885) - 543331..543849 (+) 519 WP_003687984.1 HNH endonuclease -
  V5G03_RS02890 (V5G03_02890) - 543914..544336 (+) 423 WP_003690919.1 hypothetical protein -
  V5G03_RS02895 (V5G03_02895) - 544336..544875 (+) 540 WP_003690920.1 hypothetical protein -
  V5G03_RS02900 (V5G03_02900) - 544856..546130 (+) 1275 WP_003701186.1 PBSX family phage terminase large subunit -
  V5G03_RS02905 (V5G03_02905) - 546115..548382 (+) 2268 WP_225577699.1 hypothetical protein -
  V5G03_RS02910 (V5G03_02910) - 548619..549815 (+) 1197 WP_003690925.1 hypothetical protein -
  V5G03_RS02915 (V5G03_02915) - 549812..551026 (+) 1215 WP_047954539.1 hypothetical protein -
  V5G03_RS02920 (V5G03_02920) - 553920..557024 (+) 3105 Protein_564 PLxRFG domain-containing protein -
  V5G03_RS02925 (V5G03_02925) - 557006..557743 (+) 738 WP_003702468.1 hypothetical protein -
  V5G03_RS02930 (V5G03_02930) - 557764..559059 (+) 1296 WP_003690933.1 DUF4043 family protein -
  V5G03_RS02935 (V5G03_02935) - 559114..559587 (+) 474 WP_003690936.1 hypothetical protein -
  V5G03_RS02940 (V5G03_02940) - 559593..560078 (+) 486 WP_003687997.1 hypothetical protein -
  V5G03_RS02945 (V5G03_02945) - 560075..560350 (+) 276 WP_010358526.1 hypothetical protein -
  V5G03_RS02950 (V5G03_02950) - 560341..560748 (+) 408 WP_010358525.1 hypothetical protein -
  V5G03_RS02955 (V5G03_02955) - 560751..560900 (+) 150 WP_003706419.1 hypothetical protein -
  V5G03_RS02960 (V5G03_02960) - 560937..561782 (-) 846 WP_003701197.1 Bro-N domain-containing protein -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 17443.10 Da        Isoelectric Point: 9.4067

>NTDB_id=936941 V5G03_RS02690 WP_172617250.1 522629..523102(+) (pilL) [Neisseria gonorrhoeae strain WHO_G_2024]
MEQKGFTLIEMMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDDNDTLKSKLEIFVSGYKM
NPKIAKKYSVSVRLVNEGKPRAYRLVGVPNAGTGYTLSVWMNSVGDGYKCRDATSAQAYSDTLSADSGCEAFSNRKK

Nucleotide


Download         Length: 474 bp        

>NTDB_id=936941 V5G03_RS02690 WP_172617250.1 522629..523102(+) (pilL) [Neisseria gonorrhoeae strain WHO_G_2024]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCACGATACTCGGCATTATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACGATAATGATACCCTCAAGAGCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTGCGGCTTGTCAATGAGGGAAAACCAAGGGCATACAGGTTGGTCGG
TGTTCCGAACGCGGGGACGGGTTATACTCTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCA
CTTCTGCCCAGGCCTATTCGGACACCTTGTCCGCAGATAGCGGCTGTGAAGCTTTCTCTAATCGTAAAAAATAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(3-25)

Minor type IV pilin, PilX (Pilin_PilX)

(31-157)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilL Neisseria gonorrhoeae MS11

92.994

100

0.93
  pilX Neisseria meningitidis 8013

85.35

100

0.854