Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   V5G04_RS08245 Genome accession   NZ_CP145067
Coordinates   1578004..1578453 (-) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria gonorrhoeae strain WHO_N_2024     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1574479..1585733 1578004..1578453 within 0


Gene organization within MGE regions


Location: 1574479..1585733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G04_RS08220 (V5G04_08235) - 1574479..1575075 (-) 597 WP_012503916.1 TIGR02391 family protein -
  V5G04_RS08225 (V5G04_08240) - 1575265..1576122 (-) 858 WP_012503917.1 ATP-binding protein -
  V5G04_RS08230 (V5G04_08245) - 1576136..1576465 (-) 330 WP_002234365.1 DNA cytosine methyltransferase -
  V5G04_RS08235 (V5G04_08250) - 1576504..1577112 (-) 609 WP_080229275.1 DNA cytosine methyltransferase -
  V5G04_RS08240 (V5G04_08255) - 1577481..1577627 (+) 147 WP_003691757.1 hypothetical protein -
  V5G04_RS08245 (V5G04_08260) comP 1578004..1578453 (-) 450 WP_002214937.1 type IV pilin protein Machinery gene
  V5G04_RS08250 (V5G04_08265) comE 1578541..1578936 (-) 396 WP_003703428.1 helix-hairpin-helix domain-containing protein Machinery gene
  V5G04_RS08255 (V5G04_08270) - 1579038..1579157 (-) 120 Protein_1611 competence protein ComE -
  V5G04_RS08285 (V5G04_08300) - 1584781..1585434 (-) 654 Protein_1612 TIGR01621 family pseudouridine synthase -
  V5G04_RS08290 (V5G04_08305) - 1585494..1585733 (-) 240 WP_229684458.1 HAD hydrolase family protein -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=936810 V5G04_RS08245 WP_002214937.1 1578004..1578453(-) (comP) [Neisseria gonorrhoeae strain WHO_N_2024]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=936810 V5G04_RS08245 WP_002214937.1 1578004..1578453(-) (comP) [Neisseria gonorrhoeae strain WHO_N_2024]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49