Detailed information    

insolico Bioinformatically predicted

Overview


Name   comP   Type   Machinery gene
Locus tag   V5F97_RS08440 Genome accession   NZ_CP145057
Coordinates   1622765..1623214 (-) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria gonorrhoeae strain WHO_alpha_2024     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1588925..1622516 1622765..1623214 flank 249


Gene organization within MGE regions


Location: 1588925..1623214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5F97_RS08170 (V5F97_08210) - 1588953..1589927 (-) 975 WP_003689550.1 SIS domain-containing protein -
  V5F97_RS08175 (V5F97_08215) tal 1590024..1591079 (+) 1056 WP_003689551.1 transaldolase -
  V5F97_RS08180 (V5F97_08220) - 1591091..1591225 (+) 135 WP_012503902.1 hypothetical protein -
  V5F97_RS08185 (V5F97_08225) - 1591230..1591520 (+) 291 WP_003689553.1 hypothetical protein -
  V5F97_RS08190 (V5F97_08230) gluQRS 1591537..1592424 (+) 888 WP_003689554.1 tRNA glutamyl-Q(34) synthetase GluQRS -
  V5F97_RS08195 (V5F97_08235) dusA 1592494..1593510 (-) 1017 WP_003689555.1 tRNA dihydrouridine(20/20a) synthase DusA -
  V5F97_RS08200 (V5F97_08240) - 1593630..1594784 (+) 1155 WP_047919675.1 tyrosine-type recombinase/integrase -
  V5F97_RS08205 (V5F97_08245) - 1594834..1595100 (-) 267 WP_003689557.1 pyocin activator PrtN family protein -
  V5F97_RS08210 (V5F97_08250) - 1595208..1596356 (-) 1149 WP_003705649.1 hypothetical protein -
  V5F97_RS08215 (V5F97_08255) - 1596353..1597336 (-) 984 WP_047919745.1 hypothetical protein -
  V5F97_RS08220 (V5F97_08260) - 1597447..1597662 (-) 216 WP_003691538.1 hypothetical protein -
  V5F97_RS08225 (V5F97_08265) - 1597714..1598205 (-) 492 WP_003691537.1 siphovirus Gp157 family protein -
  V5F97_RS08230 (V5F97_08270) - 1598202..1598384 (-) 183 WP_003691535.1 hypothetical protein -
  V5F97_RS08235 (V5F97_08275) - 1598524..1599210 (-) 687 WP_042758540.1 phage replication initiation protein, NGO0469 family -
  V5F97_RS08240 (V5F97_08280) - 1599279..1599440 (-) 162 WP_003702497.1 hypothetical protein -
  V5F97_RS08245 (V5F97_08285) - 1599437..1599715 (-) 279 WP_003691529.1 NGO1622 family putative holin -
  V5F97_RS08250 (V5F97_08290) - 1599868..1600200 (-) 333 WP_003687946.1 hypothetical protein -
  V5F97_RS08255 (V5F97_08295) - 1600342..1600617 (-) 276 WP_047925817.1 hypothetical protein -
  V5F97_RS08260 (V5F97_08300) - 1600614..1601090 (-) 477 WP_003691526.1 hypothetical protein -
  V5F97_RS08265 (V5F97_08305) - 1601123..1601323 (-) 201 WP_047919800.1 hypothetical protein -
  V5F97_RS08270 (V5F97_08310) - 1601544..1602305 (+) 762 WP_012503753.1 hypothetical protein -
  V5F97_RS08275 (V5F97_08315) - 1602404..1602805 (-) 402 WP_003691454.1 type II toxin-antitoxin system HicB family antitoxin -
  V5F97_RS08280 (V5F97_08320) - 1602907..1603089 (-) 183 WP_003689143.1 type II toxin-antitoxin system HicA family toxin -
  V5F97_RS08285 (V5F97_08325) - 1603259..1604077 (-) 819 WP_012503752.1 DUF3037 domain-containing protein -
  V5F97_RS08290 (V5F97_08330) - 1604074..1604772 (-) 699 WP_003689139.1 HipA family kinase -
  V5F97_RS08295 (V5F97_08335) - 1605011..1605709 (-) 699 WP_002212401.1 S24 family peptidase -
  V5F97_RS08300 (V5F97_08340) - 1605749..1606435 (-) 687 WP_012503751.1 helix-turn-helix transcriptional regulator -
  V5F97_RS08305 (V5F97_08345) - 1606651..1606785 (+) 135 WP_229684436.1 YdaS family helix-turn-helix protein -
  V5F97_RS08310 (V5F97_08350) - 1606787..1606987 (+) 201 WP_012503750.1 hypothetical protein -
  V5F97_RS08315 (V5F97_08355) - 1607184..1607990 (+) 807 WP_050154776.1 replication protein -
  V5F97_RS08320 (V5F97_08360) - 1608005..1608787 (+) 783 WP_025456432.1 ATP-binding protein -
  V5F97_RS08325 (V5F97_08365) - 1608800..1609063 (+) 264 WP_154230797.1 hypothetical protein -
  V5F97_RS08330 (V5F97_08370) - 1609102..1609596 (+) 495 WP_003691434.1 DUF3310 domain-containing protein -
  V5F97_RS08335 (V5F97_08375) - 1609773..1609922 (+) 150 WP_003689110.1 hypothetical protein -
  V5F97_RS08340 (V5F97_08380) - 1609951..1610232 (+) 282 WP_003689109.1 hypothetical protein -
  V5F97_RS08345 (V5F97_08385) - 1610223..1610603 (+) 381 WP_017147222.1 RusA family crossover junction endodeoxyribonuclease -
  V5F97_RS08350 (V5F97_08390) - 1610620..1610748 (-) 129 WP_017147221.1 hypothetical protein -
  V5F97_RS08355 (V5F97_08395) - 1610932..1611894 (-) 963 WP_050303398.1 IS110 family transposase -
  V5F97_RS08360 (V5F97_08400) - 1612406..1612765 (-) 360 WP_003689732.1 hypothetical protein -
  V5F97_RS08365 (V5F97_08405) - 1612886..1613958 (-) 1073 Protein_1634 zonular occludens toxin domain-containing protein -
  V5F97_RS08370 (V5F97_08410) - 1613968..1614258 (-) 291 WP_047917922.1 DUF2523 domain-containing protein -
  V5F97_RS08375 (V5F97_08415) - 1614237..1615826 (-) 1590 WP_012503913.1 IgG-binding virulence factor TspB family protein -
  V5F97_RS08380 (V5F97_08420) - 1615768..1616085 (-) 318 WP_003689167.1 DUF1132 family protein -
  V5F97_RS08385 (V5F97_08425) - 1616213..1616491 (-) 279 WP_003691583.1 hypothetical protein -
  V5F97_RS08390 (V5F97_08430) - 1616498..1616716 (-) 219 WP_003691584.1 major capsid protein -
  V5F97_RS08395 (V5F97_08435) - 1616790..1616987 (-) 198 WP_003689600.1 hypothetical protein -
  V5F97_RS08400 (V5F97_08440) - 1616992..1617282 (-) 291 WP_012503914.1 hypothetical protein -
  V5F97_RS08405 (V5F97_08445) - 1617327..1618673 (-) 1347 WP_082295432.1 replication initiation factor domain-containing protein -
  V5F97_RS08410 (V5F97_08450) - 1618812..1619234 (-) 423 WP_003691751.1 very short patch repair endonuclease -
  V5F97_RS08415 (V5F97_08455) - 1619240..1619836 (-) 597 WP_012503916.1 TIGR02391 family protein -
  V5F97_RS08420 (V5F97_08460) - 1620026..1620883 (-) 858 WP_012503917.1 ATP-binding protein -
  V5F97_RS08425 (V5F97_08465) - 1620897..1621268 (-) 372 WP_228841280.1 DNA cytosine methyltransferase -
  V5F97_RS08430 (V5F97_08470) - 1621265..1621873 (-) 609 WP_080229275.1 DNA cytosine methyltransferase -
  V5F97_RS08435 (V5F97_08475) - 1622242..1622388 (+) 147 WP_003691757.1 hypothetical protein -
  V5F97_RS08440 (V5F97_08480) comP 1622765..1623214 (-) 450 WP_002214937.1 type IV pilin protein Machinery gene

Sequence


Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=936618 V5F97_RS08440 WP_002214937.1 1622765..1623214(-) (comP) [Neisseria gonorrhoeae strain WHO_alpha_2024]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=936618 V5F97_RS08440 WP_002214937.1 1622765..1623214(-) (comP) [Neisseria gonorrhoeae strain WHO_alpha_2024]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1

  comP Neisseria meningitidis 8013

99.329

100

0.993

  comP Neisseria subflava NJ9703

49.66

98.658

0.49