Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACEPOS_RS00995 Genome accession   NZ_CP168497
Coordinates   202311..204092 (-) Length   593 a.a.
NCBI ID   WP_271019572.1    Uniprot ID   -
Organism   Staphylococcus aureus strain J23     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 197311..209092
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPOS_RS00975 (ACEPOS_00975) racE 197701..198501 (-) 801 WP_001039660.1 glutamate racemase -
  ACEPOS_RS00980 (ACEPOS_00980) sdhB 198742..199557 (-) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  ACEPOS_RS00985 (ACEPOS_00985) sdhA 199557..201323 (-) 1767 WP_020977171.1 succinate dehydrogenase flavoprotein subunit -
  ACEPOS_RS00990 (ACEPOS_00990) - 201375..201989 (-) 615 WP_020977170.1 succinate dehydrogenase cytochrome b558 subunit -
  ACEPOS_RS00995 (ACEPOS_00995) uvrC 202311..204092 (-) 1782 WP_271019572.1 excinuclease ABC subunit UvrC Machinery gene
  ACEPOS_RS01000 (ACEPOS_01000) - 204258..204353 (+) 96 WP_031844936.1 hypothetical protein -
  ACEPOS_RS01005 (ACEPOS_01005) trxA 204416..204730 (-) 315 WP_001018928.1 thioredoxin -
  ACEPOS_RS01010 (ACEPOS_01010) mutS/mutS2 204903..207251 (-) 2349 WP_020977169.1 endonuclease MutS2 Machinery gene
  ACEPOS_RS01015 (ACEPOS_01015) polX 207261..208973 (-) 1713 WP_020977168.1 DNA polymerase/3'-5' exonuclease PolX -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68592.22 Da        Isoelectric Point: 9.7838

>NTDB_id=936066 ACEPOS_RS00995 WP_271019572.1 202311..204092(-) (uvrC) [Staphylococcus aureus strain J23]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNSLLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGSKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGGKRKTLLLRTF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=936066 ACEPOS_RS00995 WP_271019572.1 202311..204092(-) (uvrC) [Staphylococcus aureus strain J23]
TTGGAAGACTATAAGCAACGAATTAAAAACAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGCGATCATATTTTACGGGCGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCAAGTGAAACAGAGTCACTTTTACTG
GAATTGAATCTGATTAAACAATATCAACCTAGATACAACAGTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
AACAAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCAA
ATGCATATTCTGCTCAAGAAACTAAAAAGTTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGAGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAATAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGTTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTTCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATCCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGATGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTAAAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCGGATTTAATTA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAAAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACAGGCTTGAAATCAATCCTTGATGATATAGATGGTATCGGTGGCAAACGTAAAACATTATTATTGCGTACATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTCGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(19-93)

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae R6

57.265

98.651

0.565
  uvrC Streptococcus pneumoniae D39

57.265

98.651

0.565