Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilK   Type   Machinery gene
Locus tag   V5G02_RS02690 Genome accession   NZ_CP145026
Coordinates   523282..523890 (+) Length   202 a.a.
NCBI ID   WP_047920987.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_S2_2024     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 524435..560661 523282..523890 flank 545


Gene organization within MGE regions


Location: 523282..560661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G02_RS02690 (V5G02_02690) pilK 523282..523890 (+) 609 WP_047920987.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  V5G02_RS02695 (V5G02_02695) pilL 523892..524365 (+) 474 WP_170959666.1 PilX family type IV pilin Machinery gene
  V5G02_RS02700 (V5G02_02700) - 524435..524743 (-) 309 WP_263328824.1 AzlD family protein -
  V5G02_RS02705 (V5G02_02705) - 524740..525451 (-) 712 Protein_523 AzlC family ABC transporter permease -
  V5G02_RS02710 (V5G02_02710) dut 525617..526069 (+) 453 WP_003701071.1 dUTP diphosphatase -
  V5G02_RS02715 (V5G02_02715) dapC 526141..527328 (+) 1188 WP_003701073.1 succinyldiaminopimelate transaminase -
  V5G02_RS02720 (V5G02_02720) yaaA 527484..528263 (+) 780 WP_003687925.1 peroxide stress protein YaaA -
  V5G02_RS02735 (V5G02_02735) - 528793..529993 (+) 1201 Protein_527 tyrosine-type recombinase/integrase -
  V5G02_RS02740 (V5G02_02740) - 530349..530618 (-) 270 WP_003687928.1 hypothetical protein -
  V5G02_RS02745 (V5G02_02745) - 530813..531496 (-) 684 WP_003687929.1 DUF2786 domain-containing protein -
  V5G02_RS02750 (V5G02_02750) - 531810..532043 (-) 234 Protein_530 hypothetical protein -
  V5G02_RS02755 (V5G02_02755) - 532154..532369 (-) 216 WP_003691538.1 hypothetical protein -
  V5G02_RS02760 (V5G02_02760) - 532421..532912 (-) 492 WP_047926688.1 siphovirus Gp157 family protein -
  V5G02_RS02765 (V5G02_02765) - 532909..533091 (-) 183 WP_003691535.1 hypothetical protein -
  V5G02_RS02770 (V5G02_02770) - 533231..533917 (-) 687 WP_042758540.1 phage replication initiation protein, NGO0469 family -
  V5G02_RS02775 (V5G02_02775) - 533986..534147 (-) 162 WP_003691530.1 hypothetical protein -
  V5G02_RS02780 (V5G02_02780) - 534144..534422 (-) 279 WP_003691529.1 NGO1622 family putative holin -
  V5G02_RS02785 (V5G02_02785) - 534575..534907 (-) 333 WP_047923919.1 hypothetical protein -
  V5G02_RS02790 (V5G02_02790) - 535048..535329 (-) 282 WP_196375195.1 hypothetical protein -
  V5G02_RS02795 (V5G02_02795) - 535326..535802 (-) 477 WP_012504141.1 hypothetical protein -
  V5G02_RS02800 (V5G02_02800) - 535835..536035 (-) 201 WP_124693294.1 hypothetical protein -
  V5G02_RS02805 (V5G02_02805) - 536233..536646 (-) 414 WP_003687963.1 hypothetical protein -
  V5G02_RS02810 (V5G02_02810) - 536643..537104 (-) 462 WP_003687965.1 helix-turn-helix domain-containing protein -
  V5G02_RS02815 (V5G02_02815) - 537121..537558 (-) 438 WP_003687967.1 hypothetical protein -
  V5G02_RS02820 (V5G02_02820) - 537671..538387 (-) 717 WP_003687969.1 LexA family transcriptional regulator -
  V5G02_RS02825 (V5G02_02825) - 538456..538692 (+) 237 WP_003687971.1 Cro/CI family transcriptional regulator -
  V5G02_RS02830 (V5G02_02830) - 538772..538927 (+) 156 WP_003689578.1 hypothetical protein -
  V5G02_RS02835 (V5G02_02835) - 538904..539092 (-) 189 WP_003691445.1 hypothetical protein -
  V5G02_RS02840 (V5G02_02840) - 539265..539492 (+) 228 WP_003698261.1 helix-turn-helix domain-containing protein -
  V5G02_RS02845 (V5G02_02845) - 539489..539626 (+) 138 WP_010359998.1 hypothetical protein -
  V5G02_RS02850 (V5G02_02850) - 539610..540674 (+) 1065 WP_050154676.1 hypothetical protein -
  V5G02_RS02855 (V5G02_02855) - 540671..542032 (+) 1362 WP_003689132.1 DnaB-like helicase C-terminal domain-containing protein -
  V5G02_RS02860 (V5G02_02860) - 542069..542332 (+) 264 WP_154235845.1 hypothetical protein -
  V5G02_RS02865 (V5G02_02865) - 542371..542865 (+) 495 WP_047923242.1 DUF3310 domain-containing protein -
  V5G02_RS02870 (V5G02_02870) - 543042..543191 (+) 150 WP_010360014.1 hypothetical protein -
  V5G02_RS02875 (V5G02_02875) - 543220..543501 (+) 282 WP_003689109.1 hypothetical protein -
  V5G02_RS02880 (V5G02_02880) - 543492..543866 (+) 375 WP_235430196.1 RusA family crossover junction endodeoxyribonuclease -
  V5G02_RS02885 (V5G02_02885) - 543863..544165 (+) 303 WP_050155210.1 DUF1364 domain-containing protein -
  V5G02_RS02890 (V5G02_02890) - 544162..544545 (+) 384 WP_003690918.1 recombination protein NinB -
  V5G02_RS02895 (V5G02_02895) - 544536..545054 (+) 519 WP_003687984.1 HNH endonuclease -
  V5G02_RS02900 (V5G02_02900) - 545119..545541 (+) 423 WP_003690919.1 hypothetical protein -
  V5G02_RS02905 (V5G02_02905) - 545541..546080 (+) 540 WP_003690920.1 hypothetical protein -
  V5G02_RS02910 (V5G02_02910) - 546061..547272 (+) 1212 WP_082277860.1 PBSX family phage terminase large subunit -
  V5G02_RS02915 (V5G02_02915) - 547509..548705 (+) 1197 WP_003690925.1 hypothetical protein -
  V5G02_RS02920 (V5G02_02920) - 548702..556003 (+) 7302 WP_050154634.1 PLxRFG domain-containing protein -
  V5G02_RS02925 (V5G02_02925) - 556292..556618 (+) 327 WP_229690228.1 hypothetical protein -
  V5G02_RS02930 (V5G02_02930) - 556639..557934 (+) 1296 WP_003695011.1 DUF4043 family protein -
  V5G02_RS02935 (V5G02_02935) - 557989..558462 (+) 474 WP_003687996.1 hypothetical protein -
  V5G02_RS02940 (V5G02_02940) - 558468..558953 (+) 486 WP_003687997.1 hypothetical protein -
  V5G02_RS02945 (V5G02_02945) - 558950..559624 (+) 675 WP_003695013.1 hypothetical protein -
  V5G02_RS02950 (V5G02_02950) - 559810..560661 (-) 852 WP_050154632.1 Bro-N domain-containing protein -

Sequence

Protein


Download         Length: 202 a.a.        Molecular weight: 21896.78 Da        Isoelectric Point: 8.0870

>NTDB_id=936067 V5G02_RS02690 WP_047920987.1 523282..523890(+) (pilK) [Neisseria gonorrhoeae strain WHO_S2_2024]
MRKQNALTGIPTSDGQRGSALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCEKGLCTAVNVRTNNANEESFGNIVVQGTPTVEAVKRSCPAKSGKNSTGLCIDNQGVEYKKGTASVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ

Nucleotide


Download         Length: 609 bp        

>NTDB_id=936067 V5G02_RS02690 WP_047920987.1 523282..523890(+) (pilK) [Neisseria gonorrhoeae strain WHO_S2_2024]
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGACGGACAGAGGGGGTCCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAAAGGCCTGTGTACCGCAGTGAATGTACGGACAAATAATGCTAATGA
AGAGTCTTTTGGCAATATCGTGGTGCAAGGCACGCCCACCGTTGAGGCGGTGAAGCGTTCTTGCCCTGCAAAGTCTGGCA
AAAATTCTACCGGCCTGTGCATTGACAATCAGGGAGTGGAATATAAGAAAGGCACGGCAAGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA

Domains

Predicted by InterproScan.

PilX N-terminal (PilX_N)

(17-67)

Type IV pilus assembly protein PilX C-term (PilX)

(92-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilK Neisseria gonorrhoeae MS11

95.074

100

0.955