Detailed information
Bioinformatically predicted
Overview
| Name | pilL | Type | Machinery gene |
| Locus tag | V5G02_RS02695 | Genome accession | NZ_CP145026 |
| Coordinates | 523892..524365 (+) | Length | 157 a.a. |
| NCBI ID | WP_170959666.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain WHO_S2_2024 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 524435..560661 | 523892..524365 | flank | 70 |
Gene organization within MGE regions
Location: 523892..560661
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V5G02_RS02695 (V5G02_02695) | pilL | 523892..524365 (+) | 474 | WP_170959666.1 | PilX family type IV pilin | Machinery gene |
| V5G02_RS02700 (V5G02_02700) | - | 524435..524743 (-) | 309 | WP_263328824.1 | AzlD family protein | - |
| V5G02_RS02705 (V5G02_02705) | - | 524740..525451 (-) | 712 | Protein_523 | AzlC family ABC transporter permease | - |
| V5G02_RS02710 (V5G02_02710) | dut | 525617..526069 (+) | 453 | WP_003701071.1 | dUTP diphosphatase | - |
| V5G02_RS02715 (V5G02_02715) | dapC | 526141..527328 (+) | 1188 | WP_003701073.1 | succinyldiaminopimelate transaminase | - |
| V5G02_RS02720 (V5G02_02720) | yaaA | 527484..528263 (+) | 780 | WP_003687925.1 | peroxide stress protein YaaA | - |
| V5G02_RS02735 (V5G02_02735) | - | 528793..529993 (+) | 1201 | Protein_527 | tyrosine-type recombinase/integrase | - |
| V5G02_RS02740 (V5G02_02740) | - | 530349..530618 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| V5G02_RS02745 (V5G02_02745) | - | 530813..531496 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| V5G02_RS02750 (V5G02_02750) | - | 531810..532043 (-) | 234 | Protein_530 | hypothetical protein | - |
| V5G02_RS02755 (V5G02_02755) | - | 532154..532369 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| V5G02_RS02760 (V5G02_02760) | - | 532421..532912 (-) | 492 | WP_047926688.1 | siphovirus Gp157 family protein | - |
| V5G02_RS02765 (V5G02_02765) | - | 532909..533091 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| V5G02_RS02770 (V5G02_02770) | - | 533231..533917 (-) | 687 | WP_042758540.1 | phage replication initiation protein, NGO0469 family | - |
| V5G02_RS02775 (V5G02_02775) | - | 533986..534147 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| V5G02_RS02780 (V5G02_02780) | - | 534144..534422 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| V5G02_RS02785 (V5G02_02785) | - | 534575..534907 (-) | 333 | WP_047923919.1 | hypothetical protein | - |
| V5G02_RS02790 (V5G02_02790) | - | 535048..535329 (-) | 282 | WP_196375195.1 | hypothetical protein | - |
| V5G02_RS02795 (V5G02_02795) | - | 535326..535802 (-) | 477 | WP_012504141.1 | hypothetical protein | - |
| V5G02_RS02800 (V5G02_02800) | - | 535835..536035 (-) | 201 | WP_124693294.1 | hypothetical protein | - |
| V5G02_RS02805 (V5G02_02805) | - | 536233..536646 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| V5G02_RS02810 (V5G02_02810) | - | 536643..537104 (-) | 462 | WP_003687965.1 | helix-turn-helix domain-containing protein | - |
| V5G02_RS02815 (V5G02_02815) | - | 537121..537558 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| V5G02_RS02820 (V5G02_02820) | - | 537671..538387 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| V5G02_RS02825 (V5G02_02825) | - | 538456..538692 (+) | 237 | WP_003687971.1 | Cro/CI family transcriptional regulator | - |
| V5G02_RS02830 (V5G02_02830) | - | 538772..538927 (+) | 156 | WP_003689578.1 | hypothetical protein | - |
| V5G02_RS02835 (V5G02_02835) | - | 538904..539092 (-) | 189 | WP_003691445.1 | hypothetical protein | - |
| V5G02_RS02840 (V5G02_02840) | - | 539265..539492 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| V5G02_RS02845 (V5G02_02845) | - | 539489..539626 (+) | 138 | WP_010359998.1 | hypothetical protein | - |
| V5G02_RS02850 (V5G02_02850) | - | 539610..540674 (+) | 1065 | WP_050154676.1 | hypothetical protein | - |
| V5G02_RS02855 (V5G02_02855) | - | 540671..542032 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| V5G02_RS02860 (V5G02_02860) | - | 542069..542332 (+) | 264 | WP_154235845.1 | hypothetical protein | - |
| V5G02_RS02865 (V5G02_02865) | - | 542371..542865 (+) | 495 | WP_047923242.1 | DUF3310 domain-containing protein | - |
| V5G02_RS02870 (V5G02_02870) | - | 543042..543191 (+) | 150 | WP_010360014.1 | hypothetical protein | - |
| V5G02_RS02875 (V5G02_02875) | - | 543220..543501 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| V5G02_RS02880 (V5G02_02880) | - | 543492..543866 (+) | 375 | WP_235430196.1 | RusA family crossover junction endodeoxyribonuclease | - |
| V5G02_RS02885 (V5G02_02885) | - | 543863..544165 (+) | 303 | WP_050155210.1 | DUF1364 domain-containing protein | - |
| V5G02_RS02890 (V5G02_02890) | - | 544162..544545 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| V5G02_RS02895 (V5G02_02895) | - | 544536..545054 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| V5G02_RS02900 (V5G02_02900) | - | 545119..545541 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| V5G02_RS02905 (V5G02_02905) | - | 545541..546080 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| V5G02_RS02910 (V5G02_02910) | - | 546061..547272 (+) | 1212 | WP_082277860.1 | PBSX family phage terminase large subunit | - |
| V5G02_RS02915 (V5G02_02915) | - | 547509..548705 (+) | 1197 | WP_003690925.1 | hypothetical protein | - |
| V5G02_RS02920 (V5G02_02920) | - | 548702..556003 (+) | 7302 | WP_050154634.1 | PLxRFG domain-containing protein | - |
| V5G02_RS02925 (V5G02_02925) | - | 556292..556618 (+) | 327 | WP_229690228.1 | hypothetical protein | - |
| V5G02_RS02930 (V5G02_02930) | - | 556639..557934 (+) | 1296 | WP_003695011.1 | DUF4043 family protein | - |
| V5G02_RS02935 (V5G02_02935) | - | 557989..558462 (+) | 474 | WP_003687996.1 | hypothetical protein | - |
| V5G02_RS02940 (V5G02_02940) | - | 558468..558953 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| V5G02_RS02945 (V5G02_02945) | - | 558950..559624 (+) | 675 | WP_003695013.1 | hypothetical protein | - |
| V5G02_RS02950 (V5G02_02950) | - | 559810..560661 (-) | 852 | WP_050154632.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 157 a.a. Molecular weight: 17412.10 Da Isoelectric Point: 9.3990
>NTDB_id=936068 V5G02_RS02695 WP_170959666.1 523892..524365(+) (pilL) [Neisseria gonorrhoeae strain WHO_S2_2024]
MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDDNDTLKSKLGIFVSGYKM
NPKIAKKYSVSVMFVDKEKSRAYRLVGVPNAGTGYTLSVWMNSVGDGYKCRDATSAQAYSDTLSADSGCEAFSNRKK
MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDDNDTLKSKLGIFVSGYKM
NPKIAKKYSVSVMFVDKEKSRAYRLVGVPNAGTGYTLSVWMNSVGDGYKCRDATSAQAYSDTLSADSGCEAFSNRKK
Nucleotide
Download Length: 474 bp
>NTDB_id=936068 V5G02_RS02695 WP_170959666.1 523892..524365(+) (pilL) [Neisseria gonorrhoeae strain WHO_S2_2024]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCGCGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACGATAATGATACCCTCAAGAGCAAACTGGGAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAATGTTTGTCGATAAGGAAAAATCAAGGGCATACAGGTTGGTCGG
CGTTCCGAACGCGGGGACGGGTTATACTTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCA
CTTCTGCCCAGGCCTATTCGGACACCTTGTCCGCAGATAGCGGCTGTGAAGCTTTCTCTAATCGTAAAAAATAG
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCGCGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACGATAATGATACCCTCAAGAGCAAACTGGGAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAATGTTTGTCGATAAGGAAAAATCAAGGGCATACAGGTTGGTCGG
CGTTCCGAACGCGGGGACGGGTTATACTTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCA
CTTCTGCCCAGGCCTATTCGGACACCTTGTCCGCAGATAGCGGCTGTGAAGCTTTCTCTAATCGTAAAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilL | Neisseria gonorrhoeae MS11 |
93.631 |
100 |
0.936 |
| pilX | Neisseria meningitidis 8013 |
85.987 |
100 |
0.86 |