Detailed information
Bioinformatically predicted
Overview
| Name | comP | Type | Machinery gene |
| Locus tag | V5G17_RS08460 | Genome accession | NZ_CP145024 |
| Coordinates | 1620548..1620997 (-) | Length | 149 a.a. |
| NCBI ID | WP_002214937.1 | Uniprot ID | A0AA44U8B7 |
| Organism | Neisseria gonorrhoeae strain WHO_U_2024 | ||
| Function | DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1586758..1620299 | 1620548..1620997 | flank | 249 |
Gene organization within MGE regions
Location: 1586758..1620997
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V5G17_RS08185 (V5G17_08200) | - | 1586786..1587760 (-) | 975 | WP_002245862.1 | KpsF/GutQ family sugar-phosphate isomerase | - |
| V5G17_RS08190 (V5G17_08205) | tal | 1587857..1588912 (+) | 1056 | WP_025459074.1 | transaldolase | - |
| V5G17_RS08195 (V5G17_08210) | - | 1588924..1589046 (+) | 123 | WP_257389974.1 | hypothetical protein | - |
| V5G17_RS08200 (V5G17_08215) | - | 1589051..1589341 (+) | 291 | WP_106333433.1 | hypothetical protein | - |
| V5G17_RS08205 (V5G17_08220) | gluQRS | 1589358..1590245 (+) | 888 | WP_106333435.1 | tRNA glutamyl-Q(34) synthetase GluQRS | - |
| V5G17_RS08210 (V5G17_08225) | dusA | 1590315..1591331 (-) | 1017 | WP_003689555.1 | tRNA dihydrouridine(20/20a) synthase DusA | - |
| V5G17_RS08215 (V5G17_08230) | - | 1591451..1592605 (+) | 1155 | WP_003693486.1 | tyrosine-type recombinase/integrase | - |
| V5G17_RS08220 (V5G17_08235) | - | 1592655..1592921 (-) | 267 | WP_003689557.1 | pyocin activator PrtN family protein | - |
| V5G17_RS08225 (V5G17_08240) | - | 1593029..1594177 (-) | 1149 | WP_010951305.1 | hypothetical protein | - |
| V5G17_RS08230 (V5G17_08245) | - | 1594174..1595157 (-) | 984 | WP_047952517.1 | hypothetical protein | - |
| V5G17_RS08235 (V5G17_08250) | - | 1595268..1595483 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| V5G17_RS08240 (V5G17_08255) | - | 1595535..1596026 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| V5G17_RS08245 (V5G17_08260) | - | 1596023..1596205 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| V5G17_RS08250 (V5G17_08265) | - | 1596345..1597031 (-) | 687 | WP_010359969.1 | phage replication initiation protein, NGO0469 family | - |
| V5G17_RS08255 (V5G17_08270) | - | 1597100..1597261 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| V5G17_RS08260 (V5G17_08275) | - | 1597258..1597533 (-) | 276 | WP_047917337.1 | NGO1622 family putative holin | - |
| V5G17_RS08265 (V5G17_08280) | - | 1597649..1597981 (-) | 333 | WP_003705604.1 | hypothetical protein | - |
| V5G17_RS08270 (V5G17_08285) | - | 1598122..1598397 (-) | 276 | WP_050172639.1 | hypothetical protein | - |
| V5G17_RS08275 (V5G17_08290) | - | 1598394..1598870 (-) | 477 | WP_002255718.1 | hypothetical protein | - |
| V5G17_RS08280 (V5G17_08295) | - | 1598903..1599103 (-) | 201 | WP_003687954.1 | hypothetical protein | - |
| V5G17_RS08285 (V5G17_08300) | - | 1599324..1600085 (+) | 762 | WP_012503753.1 | hypothetical protein | - |
| V5G17_RS08290 (V5G17_08305) | - | 1600184..1600585 (-) | 402 | WP_003691454.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| V5G17_RS08295 (V5G17_08310) | - | 1600687..1600869 (-) | 183 | WP_003689143.1 | type II toxin-antitoxin system HicA family toxin | - |
| V5G17_RS08300 (V5G17_08315) | - | 1601039..1601857 (-) | 819 | WP_012503752.1 | DUF3037 domain-containing protein | - |
| V5G17_RS08305 (V5G17_08320) | - | 1601854..1602552 (-) | 699 | WP_003689139.1 | HipA family kinase | - |
| V5G17_RS08310 (V5G17_08325) | - | 1602791..1603489 (-) | 699 | WP_002212401.1 | S24 family peptidase | - |
| V5G17_RS08315 (V5G17_08330) | - | 1603529..1604182 (-) | 654 | WP_157149898.1 | helix-turn-helix transcriptional regulator | - |
| V5G17_RS08320 (V5G17_08335) | - | 1604431..1604565 (+) | 135 | WP_229684436.1 | YdaS family helix-turn-helix protein | - |
| V5G17_RS08325 (V5G17_08340) | - | 1604567..1604767 (+) | 201 | WP_012503750.1 | hypothetical protein | - |
| V5G17_RS08330 (V5G17_08345) | - | 1604964..1605770 (+) | 807 | WP_050154472.1 | replication protein | - |
| V5G17_RS08335 (V5G17_08350) | - | 1605785..1606567 (+) | 783 | WP_025456432.1 | ATP-binding protein | - |
| V5G17_RS08340 (V5G17_08355) | - | 1606560..1606805 (+) | 246 | WP_082295519.1 | hypothetical protein | - |
| V5G17_RS08345 (V5G17_08360) | - | 1606881..1607375 (+) | 495 | WP_047923242.1 | DUF3310 domain-containing protein | - |
| V5G17_RS08350 (V5G17_08365) | - | 1607552..1607701 (+) | 150 | WP_106278816.1 | hypothetical protein | - |
| V5G17_RS08355 (V5G17_08370) | - | 1607730..1608011 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| V5G17_RS08360 (V5G17_08375) | - | 1608002..1608382 (+) | 381 | WP_017147222.1 | RusA family crossover junction endodeoxyribonuclease | - |
| V5G17_RS08365 (V5G17_08380) | - | 1608399..1608527 (-) | 129 | WP_012503747.1 | hypothetical protein | - |
| V5G17_RS08370 (V5G17_08385) | - | 1608711..1609673 (-) | 963 | WP_048596793.1 | IS110 family transposase | - |
| V5G17_RS08375 (V5G17_08390) | - | 1610186..1610545 (-) | 360 | WP_003691563.1 | hypothetical protein | - |
| V5G17_RS08380 (V5G17_08395) | - | 1610666..1611738 (-) | 1073 | Protein_1637 | zonular occludens toxin domain-containing protein | - |
| V5G17_RS08385 (V5G17_08400) | - | 1611748..1612038 (-) | 291 | WP_012503936.1 | DUF2523 domain-containing protein | - |
| V5G17_RS08390 (V5G17_08405) | - | 1612017..1613606 (-) | 1590 | WP_171001311.1 | IgG-binding virulence factor TspB family protein | - |
| V5G17_RS08395 (V5G17_08410) | - | 1613548..1613865 (-) | 318 | WP_003689167.1 | DUF1132 family protein | - |
| V5G17_RS08400 (V5G17_08415) | - | 1613993..1614271 (-) | 279 | WP_003691583.1 | hypothetical protein | - |
| V5G17_RS08405 (V5G17_08420) | - | 1614278..1614496 (-) | 219 | WP_003691584.1 | major capsid protein | - |
| V5G17_RS08410 (V5G17_08425) | - | 1614570..1614767 (-) | 198 | WP_003689600.1 | hypothetical protein | - |
| V5G17_RS08415 (V5G17_08430) | - | 1614772..1615062 (-) | 291 | WP_012503914.1 | hypothetical protein | - |
| V5G17_RS08420 (V5G17_08435) | - | 1615107..1616455 (-) | 1349 | Protein_1645 | replication initiation factor domain-containing protein | - |
| V5G17_RS08425 (V5G17_08440) | - | 1616594..1617016 (-) | 423 | WP_003691751.1 | very short patch repair endonuclease | - |
| V5G17_RS08430 (V5G17_08445) | - | 1617022..1617618 (-) | 597 | WP_012503916.1 | TIGR02391 family protein | - |
| V5G17_RS08435 (V5G17_08450) | - | 1617808..1618278 (-) | 471 | WP_232038207.1 | hypothetical protein | - |
| V5G17_RS08440 (V5G17_08455) | - | 1618256..1618666 (-) | 411 | WP_232038208.1 | ATP-binding protein | - |
| V5G17_RS08445 (V5G17_08460) | - | 1618680..1619114 (-) | 435 | WP_229684538.1 | DNA cytosine methyltransferase | - |
| V5G17_RS08450 (V5G17_08465) | - | 1619048..1619656 (-) | 609 | WP_080229275.1 | DNA cytosine methyltransferase | - |
| V5G17_RS08455 (V5G17_08470) | - | 1620025..1620171 (+) | 147 | WP_003691757.1 | hypothetical protein | - |
| V5G17_RS08460 (V5G17_08475) | comP | 1620548..1620997 (-) | 450 | WP_002214937.1 | type IV pilin protein | Machinery gene |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 16834.81 Da Isoelectric Point: 9.7951
>NTDB_id=936033 V5G17_RS08460 WP_002214937.1 1620548..1620997(-) (comP) [Neisseria gonorrhoeae strain WHO_U_2024]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
Nucleotide
Download Length: 450 bp
>NTDB_id=936033 V5G17_RS08460 WP_002214937.1 1620548..1620997(-) (comP) [Neisseria gonorrhoeae strain WHO_U_2024]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comP | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comP | Neisseria meningitidis 8013 |
99.329 |
100 |
0.993 |
| comP | Neisseria subflava NJ9703 |
49.66 |
98.658 |
0.49 |