Detailed information
Bioinformatically predicted
Overview
| Name | comP | Type | Machinery gene |
| Locus tag | V5G12_RS08460 | Genome accession | NZ_CP145021 |
| Coordinates | 1610078..1610527 (-) | Length | 149 a.a. |
| NCBI ID | WP_002214937.1 | Uniprot ID | A0AA44U8B7 |
| Organism | Neisseria gonorrhoeae strain WHO_V_2024 | ||
| Function | DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1577527..1609829 | 1610078..1610527 | flank | 249 |
Gene organization within MGE regions
Location: 1577527..1610527
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V5G12_RS08180 (V5G12_08195) | - | 1577555..1578529 (-) | 975 | WP_003689550.1 | SIS domain-containing protein | - |
| V5G12_RS08185 (V5G12_08200) | tal | 1578626..1579681 (+) | 1056 | WP_003689551.1 | transaldolase | - |
| V5G12_RS08190 (V5G12_08205) | - | 1579693..1579827 (+) | 135 | WP_012503902.1 | hypothetical protein | - |
| V5G12_RS08195 (V5G12_08210) | - | 1579832..1580122 (+) | 291 | WP_003689553.1 | hypothetical protein | - |
| V5G12_RS08200 (V5G12_08215) | gluQRS | 1580139..1581026 (+) | 888 | WP_003689554.1 | tRNA glutamyl-Q(34) synthetase GluQRS | - |
| V5G12_RS08205 (V5G12_08220) | dusA | 1581096..1582112 (-) | 1017 | WP_003689555.1 | tRNA dihydrouridine(20/20a) synthase DusA | - |
| V5G12_RS08210 (V5G12_08225) | - | 1582232..1583386 (+) | 1155 | WP_003697468.1 | tyrosine-type recombinase/integrase | - |
| V5G12_RS08215 (V5G12_08230) | - | 1583436..1583702 (-) | 267 | WP_003689557.1 | pyocin activator PrtN family protein | - |
| V5G12_RS08220 (V5G12_08235) | - | 1583810..1584061 (-) | 252 | WP_229687117.1 | hypothetical protein | - |
| V5G12_RS08225 (V5G12_08240) | - | 1584068..1584757 (-) | 690 | WP_229700490.1 | SAM-dependent methyltransferase | - |
| V5G12_RS08230 (V5G12_08245) | - | 1584729..1584935 (-) | 207 | WP_171000880.1 | hypothetical protein | - |
| V5G12_RS08235 (V5G12_08250) | - | 1584932..1585915 (-) | 984 | WP_047952517.1 | hypothetical protein | - |
| V5G12_RS08240 (V5G12_08255) | - | 1586026..1586241 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| V5G12_RS08245 (V5G12_08260) | - | 1586293..1586784 (-) | 492 | WP_017147227.1 | siphovirus Gp157 family protein | - |
| V5G12_RS08250 (V5G12_08265) | - | 1586781..1586963 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| V5G12_RS08255 (V5G12_08270) | - | 1587103..1587789 (-) | 687 | WP_042758540.1 | phage replication initiation protein, NGO0469 family | - |
| V5G12_RS08260 (V5G12_08275) | - | 1587858..1588019 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| V5G12_RS08265 (V5G12_08280) | - | 1588016..1588291 (-) | 276 | WP_003703838.1 | NGO1622 family putative holin | - |
| V5G12_RS08270 (V5G12_08285) | - | 1588444..1588776 (-) | 333 | WP_003687946.1 | hypothetical protein | - |
| V5G12_RS08275 (V5G12_08290) | - | 1588917..1589204 (-) | 288 | WP_115095429.1 | hypothetical protein | - |
| V5G12_RS08280 (V5G12_08295) | - | 1589201..1589677 (-) | 477 | WP_012504141.1 | hypothetical protein | - |
| V5G12_RS08285 (V5G12_08300) | - | 1589710..1589910 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| V5G12_RS08290 (V5G12_08305) | - | 1590394..1590612 (+) | 219 | WP_003691731.1 | hypothetical protein | - |
| V5G12_RS08295 (V5G12_08310) | - | 1590629..1590988 (-) | 360 | WP_003691733.1 | hypothetical protein | - |
| V5G12_RS08300 (V5G12_08315) | - | 1590989..1591528 (-) | 540 | WP_003695998.1 | Panacea domain-containing protein | - |
| V5G12_RS08305 (V5G12_08320) | - | 1591688..1592392 (-) | 705 | WP_003702453.1 | helix-turn-helix transcriptional regulator | - |
| V5G12_RS08310 (V5G12_08325) | - | 1592520..1592735 (+) | 216 | WP_223169978.1 | helix-turn-helix transcriptional regulator | - |
| V5G12_RS08315 (V5G12_08330) | - | 1592815..1592970 (+) | 156 | WP_003689578.1 | hypothetical protein | - |
| V5G12_RS08320 (V5G12_08335) | - | 1592947..1593135 (-) | 189 | WP_003706568.1 | hypothetical protein | - |
| V5G12_RS08325 (V5G12_08340) | - | 1593308..1593535 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| V5G12_RS08330 (V5G12_08345) | - | 1593532..1593669 (+) | 138 | WP_010359998.1 | hypothetical protein | - |
| V5G12_RS08335 (V5G12_08350) | - | 1594214..1594717 (+) | 504 | WP_010360005.1 | hypothetical protein | - |
| V5G12_RS08340 (V5G12_08355) | - | 1594714..1596075 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| V5G12_RS08345 (V5G12_08360) | - | 1596092..1596322 (+) | 231 | WP_115095430.1 | hypothetical protein | - |
| V5G12_RS08350 (V5G12_08365) | - | 1596414..1596908 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| V5G12_RS08355 (V5G12_08370) | - | 1597085..1597234 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| V5G12_RS08360 (V5G12_08375) | - | 1597262..1597543 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| V5G12_RS08365 (V5G12_08380) | - | 1597534..1597914 (+) | 381 | WP_232038250.1 | RusA family crossover junction endodeoxyribonuclease | - |
| V5G12_RS08370 (V5G12_08385) | - | 1597931..1598059 (-) | 129 | WP_017147221.1 | hypothetical protein | - |
| V5G12_RS08375 (V5G12_08390) | - | 1598243..1599205 (-) | 963 | WP_050156280.1 | IS110-like element ISNgo2 family transposase | - |
| V5G12_RS08380 (V5G12_08395) | - | 1599719..1600078 (-) | 360 | WP_003691563.1 | hypothetical protein | - |
| V5G12_RS08385 (V5G12_08400) | - | 1600199..1601284 (-) | 1086 | WP_064661608.1 | zonular occludens toxin domain-containing protein | - |
| V5G12_RS08390 (V5G12_08405) | - | 1601294..1601584 (-) | 291 | WP_012503936.1 | DUF2523 domain-containing protein | - |
| V5G12_RS08395 (V5G12_08410) | - | 1601563..1603152 (-) | 1590 | WP_171000878.1 | IgG-binding virulence factor TspB family protein | - |
| V5G12_RS08400 (V5G12_08415) | - | 1603094..1603411 (-) | 318 | WP_003689167.1 | DUF1132 family protein | - |
| V5G12_RS08405 (V5G12_08420) | - | 1603539..1603817 (-) | 279 | WP_003689168.1 | hypothetical protein | - |
| V5G12_RS08410 (V5G12_08425) | - | 1603824..1604042 (-) | 219 | WP_003691584.1 | major capsid protein | - |
| V5G12_RS08415 (V5G12_08430) | - | 1604116..1604313 (-) | 198 | WP_003689600.1 | hypothetical protein | - |
| V5G12_RS08420 (V5G12_08435) | - | 1604318..1604608 (-) | 291 | WP_002216601.1 | hypothetical protein | - |
| V5G12_RS08425 (V5G12_08440) | - | 1604653..1605986 (-) | 1334 | Protein_1646 | replication initiation factor domain-containing protein | - |
| V5G12_RS08430 (V5G12_08445) | - | 1606125..1606547 (-) | 423 | WP_003691751.1 | very short patch repair endonuclease | - |
| V5G12_RS08435 (V5G12_08450) | - | 1606553..1607149 (-) | 597 | WP_012503916.1 | TIGR02391 family protein | - |
| V5G12_RS08440 (V5G12_08455) | - | 1607339..1608196 (-) | 858 | WP_012503917.1 | ATP-binding protein | - |
| V5G12_RS08445 (V5G12_08460) | - | 1608210..1608539 (-) | 330 | WP_002234365.1 | DNA cytosine methyltransferase | - |
| V5G12_RS08450 (V5G12_08465) | - | 1608578..1609186 (-) | 609 | WP_080229275.1 | DNA cytosine methyltransferase | - |
| V5G12_RS08455 (V5G12_08470) | - | 1609555..1609701 (+) | 147 | WP_003691757.1 | hypothetical protein | - |
| V5G12_RS08460 (V5G12_08475) | comP | 1610078..1610527 (-) | 450 | WP_002214937.1 | type IV pilin protein | Machinery gene |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 16834.81 Da Isoelectric Point: 9.7951
>NTDB_id=935988 V5G12_RS08460 WP_002214937.1 1610078..1610527(-) (comP) [Neisseria gonorrhoeae strain WHO_V_2024]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK
Nucleotide
Download Length: 450 bp
>NTDB_id=935988 V5G12_RS08460 WP_002214937.1 1610078..1610527(-) (comP) [Neisseria gonorrhoeae strain WHO_V_2024]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comP | Neisseria gonorrhoeae MS11 |
100 |
100 |
1 |
| comP | Neisseria meningitidis 8013 |
99.329 |
100 |
0.993 |
| comP | Neisseria subflava NJ9703 |
49.66 |
98.658 |
0.49 |