Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   V5G14_RS01085 Genome accession   NZ_CP145017
Coordinates   221867..222316 (+) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria gonorrhoeae strain WHO_Y_2024     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 214587..227738 221867..222316 within 0


Gene organization within MGE regions


Location: 214587..227738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5G14_RS01040 (V5G14_01050) - 214587..214931 (+) 345 WP_003691787.1 HAD hydrolase family protein -
  V5G14_RS01045 (V5G14_01055) - 214885..215538 (+) 654 Protein_205 TIGR01621 family pseudouridine synthase -
  V5G14_RS01075 (V5G14_01085) - 221163..221282 (+) 120 Protein_206 competence protein ComE -
  V5G14_RS01080 (V5G14_01090) comE 221384..221779 (+) 396 WP_003703428.1 helix-hairpin-helix domain-containing protein Machinery gene
  V5G14_RS01085 (V5G14_01095) comP 221867..222316 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  V5G14_RS01090 (V5G14_01100) - 222693..222839 (-) 147 WP_003691757.1 hypothetical protein -
  V5G14_RS01095 (V5G14_01105) - 223226..223816 (+) 591 WP_080229150.1 DNA cytosine methyltransferase -
  V5G14_RS01100 (V5G14_01110) - 223813..224184 (+) 372 WP_012503918.1 DNA cytosine methyltransferase -
  V5G14_RS01105 (V5G14_01115) - 224198..225055 (+) 858 WP_012503917.1 ATP-binding protein -
  V5G14_RS01110 (V5G14_01120) - 225245..225841 (+) 597 WP_012503916.1 TIGR02391 family protein -
  V5G14_RS01115 (V5G14_01125) - 225847..226269 (+) 423 WP_003691751.1 very short patch repair endonuclease -
  V5G14_RS01120 (V5G14_01130) - 226408..227738 (+) 1331 Protein_215 replication initiation factor domain-containing protein -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=935869 V5G14_RS01085 WP_002214937.1 221867..222316(+) (comP) [Neisseria gonorrhoeae strain WHO_Y_2024]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=935869 V5G14_RS01085 WP_002214937.1 221867..222316(+) (comP) [Neisseria gonorrhoeae strain WHO_Y_2024]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49