Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   V2K10_RS08845 Genome accession   NZ_CP167067
Coordinates   1769719..1770315 (-) Length   198 a.a.
NCBI ID   WP_002991359.1    Uniprot ID   Q1JJH3
Organism   Streptococcus pyogenes strain Isolate 21     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1764719..1775315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V2K10_RS08810 (V2K10_008810) - 1764780..1765085 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  V2K10_RS08815 (V2K10_008815) ruvX 1765097..1765516 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  V2K10_RS08820 (V2K10_008820) - 1765513..1765782 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  V2K10_RS08825 (V2K10_008825) spx 1765895..1766293 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  V2K10_RS08830 (V2K10_008830) recA 1766584..1767720 (-) 1137 WP_002982186.1 recombinase RecA Machinery gene
  V2K10_RS08835 (V2K10_008835) cinA 1767809..1769080 (-) 1272 WP_002991356.1 competence/damage-inducible protein A Machinery gene
  V2K10_RS08840 (V2K10_008840) - 1769149..1769709 (-) 561 WP_002991358.1 DNA-3-methyladenine glycosylase I -
  V2K10_RS08845 (V2K10_008845) ruvA 1769719..1770315 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA Machinery gene
  V2K10_RS08850 (V2K10_008850) - 1770317..1771537 (-) 1221 WP_002991361.1 MFS transporter -
  V2K10_RS08855 (V2K10_008855) hexB 1771548..1773530 (-) 1983 WP_002991363.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21841.15 Da        Isoelectric Point: 6.2537

>NTDB_id=931995 V2K10_RS08845 WP_002991359.1 1769719..1770315(-) (ruvA) [Streptococcus pyogenes strain Isolate 21]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=931995 V2K10_RS08845 WP_002991359.1 1769719..1770315(-) (ruvA) [Streptococcus pyogenes strain Isolate 21]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT
GGCCCCACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAGACGGCAGAGCAATA
CATCAAATCAGCATTGAAACTGTTAATGAAAGGGTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Helix-hairpin-helix domain (HHH_5)

(71-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JJH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae R6

67.513

99.495

0.672
  ruvA Streptococcus pneumoniae D39

67.513

99.495

0.672
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424