Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   ACB352_RS09280 Genome accession   NZ_CP167009
Coordinates   1835134..1835730 (-) Length   198 a.a.
NCBI ID   WP_011285268.1    Uniprot ID   Q48QW4
Organism   Streptococcus pyogenes strain Isolate 22     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1830134..1840730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB352_RS09245 (ACB352_09245) - 1830194..1830499 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  ACB352_RS09250 (ACB352_09250) ruvX 1830511..1830930 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  ACB352_RS09255 (ACB352_09255) - 1830927..1831196 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  ACB352_RS09260 (ACB352_09260) spx 1831310..1831708 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  ACB352_RS09265 (ACB352_09265) recA 1831999..1833135 (-) 1137 WP_011285265.1 recombinase RecA Machinery gene
  ACB352_RS09270 (ACB352_09270) cinA 1833224..1834495 (-) 1272 WP_011285266.1 competence/damage-inducible protein A Machinery gene
  ACB352_RS09275 (ACB352_09275) - 1834564..1835124 (-) 561 WP_011018314.1 DNA-3-methyladenine glycosylase I -
  ACB352_RS09280 (ACB352_09280) ruvA 1835134..1835730 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA Machinery gene
  ACB352_RS09285 (ACB352_09285) - 1835732..1836952 (-) 1221 WP_011285269.1 MFS transporter -
  ACB352_RS09290 (ACB352_09290) hexB 1836963..1838945 (-) 1983 WP_021340699.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACB352_RS09295 (ACB352_09295) - 1839040..1840191 (-) 1152 WP_003058754.1 site-specific integrase -
  ACB352_RS09300 (ACB352_09300) - 1840440..1840583 (+) 144 WP_011185066.1 putative holin-like toxin -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21811.12 Da        Isoelectric Point: 6.2537

>NTDB_id=930486 ACB352_RS09280 WP_011285268.1 1835134..1835730(-) (ruvA) [Streptococcus pyogenes strain Isolate 22]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=930486 ACB352_RS09280 WP_011285268.1 1835134..1835730(-) (ruvA) [Streptococcus pyogenes strain Isolate 22]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT
GGCCCCACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48QW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae R6

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae D39

67.005

99.495

0.667
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424