Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   ACB352_RS04225 Genome accession   NZ_CP167009
Coordinates   817336..819327 (+) Length   663 a.a.
NCBI ID   WP_011284900.1    Uniprot ID   Q48SZ1
Organism   Streptococcus pyogenes strain Isolate 22     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 812336..824327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB352_RS04205 (ACB352_04205) - 812554..813933 (+) 1380 WP_002992849.1 PTS sugar transporter subunit IIC -
  ACB352_RS04210 (ACB352_04210) - 813930..814082 (+) 153 WP_003062002.1 hypothetical protein -
  ACB352_RS04215 (ACB352_04215) - 814230..814970 (-) 741 WP_011284902.1 amino acid ABC transporter ATP-binding protein -
  ACB352_RS04220 (ACB352_04220) - 814970..817144 (-) 2175 WP_011284901.1 ABC transporter substrate-binding protein/permease -
  ACB352_RS04225 (ACB352_04225) uvrB 817336..819327 (+) 1992 WP_011284900.1 excinuclease ABC subunit UvrB Machinery gene
  ACB352_RS04230 (ACB352_04230) - 819591..819734 (+) 144 WP_002984200.1 teichoic acid D-Ala incorporation-associated protein DltX -
  ACB352_RS04235 (ACB352_04235) dltA 819746..821284 (+) 1539 WP_011284899.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  ACB352_RS04240 (ACB352_04240) dltB 821281..822537 (+) 1257 WP_002994626.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  ACB352_RS04245 (ACB352_04245) dltC 822555..822794 (+) 240 WP_002984216.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  ACB352_RS04250 (ACB352_04250) dltD 822787..824037 (+) 1251 WP_002984219.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75678.74 Da        Isoelectric Point: 4.6420

>NTDB_id=930449 ACB352_RS04225 WP_011284900.1 817336..819327(+) (uvrB) [Streptococcus pyogenes strain Isolate 22]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIIYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=930449 ACB352_RS04225 WP_011284900.1 817336..819327(+) (uvrB) [Streptococcus pyogenes strain Isolate 22]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATTGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATACTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGATCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTATCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGGACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGGGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCGAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

Type III restriction enzyme, res subunit (ResIII)

(17-142)

Helicase conserved C-terminal domain (Helicase_C)

(443-548)

UvrB/uvrC motif (UVR)

(627-660)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48SZ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

84.917

100

0.849
  uvrB Streptococcus pneumoniae D39

84.917

100

0.849
  uvrB Streptococcus pneumoniae TIGR4

84.766

100

0.848