Detailed information    

insolico Bioinformatically predicted

Overview

Name   comZ   Type   Machinery gene
Locus tag   MWM13_RS06840 Genome accession   NZ_AP025609
Coordinates   1280803..1282479 (+) Length   558 a.a.
NCBI ID   WP_244347492.1    Uniprot ID   -
Organism   Thermus thermophilus strain SNM3-3     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1275803..1287479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM13_RS06815 (TthSNM33_13500) ilvB 1276019..1277707 (-) 1689 WP_244347489.1 biosynthetic-type acetolactate synthase large subunit -
  MWM13_RS06820 (TthSNM33_13510) - 1277863..1278843 (-) 981 WP_244340523.1 YpdA family putative bacillithiol disulfide reductase -
  MWM13_RS06825 (TthSNM33_13520) pilA/pilA1 1279009..1279479 (+) 471 WP_244347490.1 GspH/FimT family protein Machinery gene
  MWM13_RS06830 (TthSNM33_13530) pilA/pilA2 1279513..1280094 (+) 582 WP_011173284.1 type II secretion system protein Machinery gene
  MWM13_RS06835 (TthSNM33_13540) pilA/pilA3 1280091..1280792 (+) 702 WP_244347491.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  MWM13_RS06840 (TthSNM33_13550) comZ 1280803..1282479 (+) 1677 WP_244347492.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  MWM13_RS06845 (TthSNM33_13560) - 1282712..1283077 (+) 366 WP_244347493.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  MWM13_RS06850 (TthSNM33_13570) - 1283137..1283508 (+) 372 WP_244347494.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  MWM13_RS06855 (TthSNM33_13590) - 1283695..1284174 (+) 480 WP_244340535.1 DUF1640 domain-containing protein -
  MWM13_RS06860 - 1284250..1284787 (+) 538 Protein_1334 Uma2 family endonuclease -
  MWM13_RS06865 (TthSNM33_13610) - 1284810..1285109 (+) 300 WP_008631315.1 nucleotidyltransferase -
  MWM13_RS06870 (TthSNM33_13620) - 1285096..1285458 (+) 363 WP_060384345.1 HepT-like ribonuclease domain-containing protein -
  MWM13_RS06875 (TthSNM33_13630) - 1285492..1286049 (-) 558 WP_244347495.1 Uma2 family endonuclease -
  MWM13_RS06880 (TthSNM33_13640) - 1286068..1286724 (-) 657 WP_223968486.1 chromosome segregation protein ScpA -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 59796.60 Da        Isoelectric Point: 8.1208

>NTDB_id=93015 MWM13_RS06840 WP_244347492.1 1280803..1282479(+) (comZ) [Thermus thermophilus strain SNM3-3]
MNRKGIALVATLALMVVIALLVFGTFFTTQIELWTTRNDTTSVQAFYAAEAGLQKYKAVLFQQYVWREKQGGTGGGSGCF
TPLVNGLDLDRNGTLIPFTNNQLVLAENEAVMDAFGNPVGRYRVVLYKDAQDGQLFTLVSQGTSSGAKATVQATFRISNT
GYLEQAIFAGTGQANRWLNGGATIRGGIYVVGNPNDPDQYVIEANGNFALYNWYDLNTYSGVANRVEPSYQRAQDLCASL
RVQYGKISVGGSTQIGEPNNKVKGVFVGRGAQDITGQNVGVCQNNKGVCTEAMGGFDLSDPPPFPTLDAKLDSDACSAYP
TWRACLQGKAALRIQRIGNILSVASPPNATLPPSCLQAMESGTLTLDTQSVDCTFTRLDGSRGGFNYTYTGDKKSGQGLL
EVFGDVVLEGIDVVLNRPVDYRAQSGSAKSATLAVPKLSGKGGNLDINGNLLPDATFGLFPNHALGLVAEGDVYQRGQYV
MAPVYAGGTFRVVKDNVLFGSVISNQFCTTSAGNQTQCNAGQKAEVVYIRIPKENRPVLLPSLRGGKPVFQVLSYERR

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=93015 MWM13_RS06840 WP_244347492.1 1280803..1282479(+) (comZ) [Thermus thermophilus strain SNM3-3]
GTGAACCGCAAAGGTATCGCCCTTGTAGCCACTTTGGCCCTCATGGTGGTCATCGCCCTCTTGGTCTTCGGCACCTTCTT
CACCACCCAGATAGAGCTCTGGACCACCCGCAACGACACCACCTCGGTCCAGGCTTTCTACGCCGCCGAGGCCGGGCTCC
AGAAGTACAAGGCCGTCCTCTTCCAGCAGTATGTCTGGCGGGAGAAGCAGGGCGGGACCGGAGGAGGCAGCGGCTGTTTC
ACCCCCCTCGTGAACGGCCTGGACCTGGACCGGAACGGGACCCTAATCCCCTTCACCAACAACCAGTTGGTCCTGGCCGA
GAACGAGGCGGTGATGGACGCCTTCGGCAACCCCGTGGGCCGGTATCGGGTGGTCCTGTACAAGGACGCCCAAGACGGCC
AGCTTTTCACCCTGGTCTCCCAGGGCACCTCCTCCGGCGCCAAGGCCACGGTCCAGGCCACCTTCCGCATCAGCAACACG
GGCTACCTGGAGCAGGCCATCTTCGCAGGAACGGGCCAGGCCAACCGGTGGCTGAACGGGGGGGCCACCATCCGGGGCGG
AATCTACGTGGTGGGAAACCCTAACGACCCGGACCAGTACGTCATAGAGGCCAACGGCAACTTCGCCCTCTACAACTGGT
ATGACCTTAACACCTACTCCGGGGTCGCCAACCGGGTGGAACCCAGCTACCAGCGGGCCCAGGACCTCTGCGCAAGCCTT
AGGGTGCAGTATGGCAAGATTTCCGTGGGAGGAAGCACCCAGATTGGCGAGCCCAACAACAAGGTGAAGGGGGTCTTCGT
GGGCCGGGGCGCCCAAGACATCACTGGGCAGAACGTGGGCGTATGCCAGAACAACAAAGGGGTCTGCACCGAGGCCATGG
GGGGCTTTGACCTCTCCGACCCGCCCCCCTTCCCCACCCTGGACGCCAAGCTGGATTCCGACGCCTGCAGCGCCTACCCC
ACCTGGCGGGCCTGCCTCCAGGGCAAGGCCGCTTTAAGAATCCAGCGCATTGGGAACATCCTCTCCGTGGCCAGCCCGCC
TAACGCCACCTTGCCCCCATCTTGCCTCCAAGCCATGGAGTCCGGCACCCTGACCCTGGATACCCAAAGCGTGGACTGCA
CCTTCACCCGTCTGGACGGAAGCCGGGGAGGGTTCAACTACACCTACACGGGCGACAAGAAGAGCGGGCAGGGGCTTTTG
GAGGTCTTCGGCGACGTGGTGCTGGAGGGCATAGACGTGGTGCTCAACCGGCCCGTGGACTATAGGGCCCAGTCGGGAAG
CGCCAAGAGCGCCACCCTTGCGGTGCCAAAGCTTTCTGGAAAAGGCGGCAACCTGGACATCAACGGCAACCTCCTCCCCG
ACGCCACCTTTGGCCTCTTCCCCAACCATGCCCTAGGCCTCGTGGCCGAAGGAGACGTCTACCAGCGTGGCCAGTACGTG
ATGGCCCCTGTGTACGCCGGGGGCACCTTCCGGGTGGTGAAGGACAACGTCCTCTTCGGCTCGGTCATTAGCAACCAGTT
CTGCACCACGAGCGCCGGGAACCAAACGCAATGCAACGCCGGCCAGAAGGCCGAGGTGGTCTACATCCGCATCCCCAAGG
AAAACCGCCCCGTCCTCCTGCCGAGCCTCCGCGGGGGAAAGCCCGTCTTTCAGGTGCTCTCCTACGAGCGCCGCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comZ Thermus thermophilus HB27

89.606

100

0.896

Multiple sequence alignment