Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   ACB354_RS05600 Genome accession   NZ_CP167004
Coordinates   1037998..1039989 (-) Length   663 a.a.
NCBI ID   WP_011184623.1    Uniprot ID   Q5XBN4
Organism   Streptococcus pyogenes strain Isolate 28     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1032998..1044989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB354_RS05575 (ACB354_05575) dltD 1033289..1034539 (-) 1251 WP_002984219.1 D-alanyl-lipoteichoic acid biosynthesis protein DltD -
  ACB354_RS05580 (ACB354_05580) dltC 1034532..1034771 (-) 240 WP_002984216.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  ACB354_RS05585 (ACB354_05585) dltB 1034789..1036045 (-) 1257 WP_002994626.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  ACB354_RS05590 (ACB354_05590) dltA 1036042..1037580 (-) 1539 WP_002989572.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  ACB354_RS05595 (ACB354_05595) - 1037592..1037735 (-) 144 WP_002984200.1 teichoic acid D-Ala incorporation-associated protein DltX -
  ACB354_RS05600 (ACB354_05600) uvrB 1037998..1039989 (-) 1992 WP_011184623.1 excinuclease ABC subunit UvrB Machinery gene
  ACB354_RS05605 (ACB354_05605) - 1040181..1042355 (+) 2175 WP_011184624.1 ABC transporter substrate-binding protein/permease -
  ACB354_RS05610 (ACB354_05610) - 1042355..1043095 (+) 741 WP_002989563.1 amino acid ABC transporter ATP-binding protein -
  ACB354_RS05615 (ACB354_05615) - 1043243..1043395 (-) 153 WP_003062002.1 hypothetical protein -
  ACB354_RS05620 (ACB354_05620) - 1043392..1044771 (-) 1380 WP_011184625.1 PTS sugar transporter subunit IIC -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 75690.80 Da        Isoelectric Point: 4.6420

>NTDB_id=929985 ACB354_RS05600 WP_011184623.1 1037998..1039989(-) (uvrB) [Streptococcus pyogenes strain Isolate 28]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RLPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=929985 ACB354_RS05600 WP_011184623.1 1037998..1039989(-) (uvrB) [Streptococcus pyogenes strain Isolate 28]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGTCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGGAAAACTATT
GGAGAAGTTGATCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTTACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGCCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGAACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTTCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGAGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAGCTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)

Helicase conserved C-terminal domain (Helicase_C)

(443-548)

UvrB/uvrC motif (UVR)

(627-660)

Type III restriction enzyme, res subunit (ResIII)

(17-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5XBN4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

84.917

100

0.849
  uvrB Streptococcus pneumoniae D39

84.917

100

0.849
  uvrB Streptococcus pneumoniae TIGR4

84.766

100

0.848