Detailed information    

insolico Bioinformatically predicted

Overview

Name   comZ   Type   Machinery gene
Locus tag   MWM12_RS06485 Genome accession   NZ_AP025603
Coordinates   1181206..1182882 (+) Length   558 a.a.
NCBI ID   WP_244340529.1    Uniprot ID   -
Organism   Thermus thermophilus strain SNM1-7     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1176206..1187882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MWM12_RS06460 (TthSNM17_12650) ilvB 1176422..1178110 (-) 1689 WP_244340521.1 biosynthetic-type acetolactate synthase large subunit -
  MWM12_RS06465 (TthSNM17_12660) - 1178266..1179246 (-) 981 WP_244340523.1 YpdA family putative bacillithiol disulfide reductase -
  MWM12_RS06470 (TthSNM17_12670) pilA/pilA1 1179411..1179881 (+) 471 WP_165739610.1 GspH/FimT family protein Machinery gene
  MWM12_RS06475 (TthSNM17_12680) pilA/pilA2 1179916..1180497 (+) 582 WP_244340525.1 type II secretion system protein Machinery gene
  MWM12_RS06480 (TthSNM17_12690) pilA/pilA3 1180494..1181195 (+) 702 WP_244340527.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  MWM12_RS06485 (TthSNM17_12700) comZ 1181206..1182882 (+) 1677 WP_244340529.1 pilus assembly PilX N-terminal domain-containing protein Machinery gene
  MWM12_RS06490 (TthSNM17_12710) - 1183105..1183545 (+) 441 WP_244340531.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  MWM12_RS06495 (TthSNM17_12720) - 1183618..1183977 (+) 360 WP_244340533.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  MWM12_RS06500 (TthSNM17_12730) - 1184215..1184694 (+) 480 WP_244340535.1 DUF1640 domain-containing protein -
  MWM12_RS06505 - 1184770..1185307 (+) 538 Protein_1259 Uma2 family endonuclease -
  MWM12_RS06510 (TthSNM17_12750) - 1185330..1185629 (+) 300 WP_008631315.1 nucleotidyltransferase -
  MWM12_RS06515 (TthSNM17_12760) - 1185616..1185978 (+) 363 WP_060384345.1 HepT-like ribonuclease domain-containing protein -
  MWM12_RS06520 (TthSNM17_12770) - 1186012..1186569 (-) 558 WP_244340537.1 Uma2 family endonuclease -
  MWM12_RS06525 (TthSNM17_12780) - 1186588..1187244 (-) 657 WP_244340539.1 chromosome segregation protein ScpA -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 59733.30 Da        Isoelectric Point: 7.3593

>NTDB_id=92987 MWM12_RS06485 WP_244340529.1 1181206..1182882(+) (comZ) [Thermus thermophilus strain SNM1-7]
MNRKGIALVATLALMVVIALLVFGTFFTTQIELWTTRNDTTSVQAFYAAEAGLQKYKAALFQQYVWREQQGGTGGGSGCF
TSLARGLDLDRDGTLTPFVNNRLVLAQDEVVTDANGNPVGRYTVTLYKDAEDGQLFTLVSEGTSGGAKARVQATFRISNS
DYLEQAIFAGAGQANKWLNGGATIRGGVYVVGSPNDPDQYVIEANGNFALYNWYDLNTYSGVANRVEPSYQRAQDLCASL
RVQYGKISVGGSTQIGEPNNKVKGVFVGRGAQDITGQNVGVCQNNKGVCTEAMGGFDLSDPPPFPTLDAKLDSDACSAYP
TWRACLQGKAALRIQRIGNILSVASPPNATLPPSCLQAMESGTLTLDTQSVDCTFTRLDGSRGGFNYTYTGDKKSGQGLL
EVFGDVVLEGIDVVLNRPVDYRAQSGSAKSATLAVPKLSGKGGNLDINGNLLPDATFGLFPNHALGFLAEGDIYQRGQYV
MAPLYAGGTFRVVKDNVLFGSVISNQFCTTSAGNQTNCNAGQKAEVVYIRIPKENRPVLLPSLRGGKPVFQVLSYERR

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=92987 MWM12_RS06485 WP_244340529.1 1181206..1182882(+) (comZ) [Thermus thermophilus strain SNM1-7]
GTGAACCGCAAAGGTATCGCCCTTGTAGCCACTTTGGCCCTCATGGTGGTCATCGCCCTCTTGGTCTTCGGCACCTTCTT
CACCACCCAGATAGAGCTCTGGACCACCCGCAACGACACCACCTCGGTCCAGGCTTTCTACGCCGCCGAGGCCGGGCTCC
AGAAGTACAAGGCCGCCCTCTTCCAGCAGTACGTCTGGCGGGAGCAGCAGGGCGGGACGGGCGGAGGTAGCGGCTGCTTC
ACCTCCCTGGCAAGGGGGCTAGACCTGGACCGGGATGGAACCCTCACCCCCTTCGTCAACAACCGGCTGGTCCTGGCGCA
AGACGAGGTGGTCACCGACGCCAACGGCAACCCCGTGGGGCGGTACACGGTAACCCTTTACAAGGACGCCGAAGACGGCC
AGCTCTTCACCTTGGTCTCCGAGGGCACCTCGGGCGGGGCCAAGGCCCGGGTCCAGGCCACCTTTCGCATCAGCAACTCG
GACTACCTGGAGCAGGCCATCTTCGCCGGCGCGGGCCAGGCCAACAAGTGGCTGAACGGCGGGGCCACCATCCGGGGCGG
GGTCTACGTGGTGGGAAGCCCTAACGACCCGGACCAGTACGTCATAGAGGCCAACGGCAACTTCGCCCTCTACAACTGGT
ATGACCTTAACACCTACTCCGGGGTCGCCAACCGGGTGGAACCCAGCTACCAGCGGGCCCAGGACCTCTGCGCAAGCCTT
AGGGTGCAGTATGGCAAGATTTCCGTGGGAGGAAGCACCCAGATTGGCGAGCCCAACAACAAGGTGAAGGGGGTCTTCGT
GGGCCGGGGCGCCCAAGACATCACTGGGCAGAACGTGGGCGTATGCCAGAACAACAAAGGGGTCTGCACCGAGGCCATGG
GGGGCTTTGACCTCTCCGACCCGCCCCCCTTCCCCACCCTGGACGCCAAGCTGGATTCCGACGCCTGCAGCGCCTACCCC
ACCTGGCGGGCCTGCCTCCAGGGCAAGGCCGCTTTAAGAATCCAGCGCATTGGGAACATCCTCTCCGTGGCCAGCCCGCC
TAACGCCACCTTGCCCCCATCTTGCCTCCAAGCCATGGAGTCCGGCACCCTGACCCTGGATACCCAAAGCGTGGACTGCA
CCTTCACCCGTCTGGACGGAAGCCGGGGAGGGTTCAACTACACCTACACGGGCGACAAGAAGAGCGGGCAGGGGCTTTTG
GAGGTCTTCGGCGACGTGGTGCTGGAGGGCATAGACGTGGTGCTCAACCGGCCCGTGGACTATAGGGCCCAGTCGGGAAG
CGCCAAGAGCGCCACCCTTGCGGTGCCAAAGCTTTCTGGAAAAGGCGGCAACCTGGACATCAACGGCAACCTCCTCCCCG
ACGCCACCTTTGGCCTCTTCCCCAACCATGCCCTGGGTTTTCTGGCCGAAGGAGACATCTACCAGCGCGGCCAGTACGTG
ATGGCCCCCCTGTACGCCGGGGGCACCTTCCGGGTGGTGAAGGACAACGTCCTCTTCGGCTCGGTCATTAGCAACCAGTT
CTGCACCACGAGCGCCGGGAACCAAACGAACTGCAACGCCGGCCAGAAGGCCGAGGTGGTCTACATCCGCATCCCCAAGG
AAAACCGCCCCGTCCTCCTGCCGAGCCTCCGCGGGGGGAAGCCTGTCTTCCAGGTGCTCTCCTACGAGCGCCGCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comZ Thermus thermophilus HB27

93.19

100

0.932

Multiple sequence alignment