Detailed information NTG0092986

Bioinformatically predicted

Overview

• Name: pilA/pilA3
• Type: Machinery gene
• Locus tag: MWM12_RS06480
• Genome accession: NZ_AP025603
• Coordinates: 1180494..1181195 (+)
• Length: 233 a.a.
• NCBI ID: WP_244340527.1
• Uniprot ID: -
• Organism: Thermus thermophilus strain SNM1-7
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1175494..1186195

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MWM12_RS06455 (TthSNM17_12640)	ilvN	1175913..1176425 (-)	513	WP_011173280.1	acetolactate synthase small subunit	-
MWM12_RS06460 (TthSNM17_12650)	ilvB	1176422..1178110 (-)	1689	WP_244340521.1	biosynthetic-type acetolactate synthase large subunit	-
MWM12_RS06465 (TthSNM17_12660)	-	1178266..1179246 (-)	981	WP_244340523.1	YpdA family putative bacillithiol disulfide reductase	-
MWM12_RS06470 (TthSNM17_12670)	pilA/pilA1	1179411..1179881 (+)	471	WP_165739610.1	GspH/FimT family protein	Machinery gene
MWM12_RS06475 (TthSNM17_12680)	pilA/pilA2	1179916..1180497 (+)	582	WP_244340525.1	type II secretion system protein	Machinery gene
MWM12_RS06480 (TthSNM17_12690)	pilA/pilA3	1180494..1181195 (+)	702	WP_244340527.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
MWM12_RS06485 (TthSNM17_12700)	comZ	1181206..1182882 (+)	1677	WP_244340529.1	pilus assembly PilX N-terminal domain-containing protein	Machinery gene
MWM12_RS06490 (TthSNM17_12710)	-	1183105..1183545 (+)	441	WP_244340531.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
MWM12_RS06495 (TthSNM17_12720)	-	1183618..1183977 (+)	360	WP_244340533.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
MWM12_RS06500 (TthSNM17_12730)	-	1184215..1184694 (+)	480	WP_244340535.1	DUF1640 domain-containing protein	-
MWM12_RS06505	-	1184770..1185307 (+)	538	Protein_1259	Uma2 family endonuclease	-
MWM12_RS06510 (TthSNM17_12750)	-	1185330..1185629 (+)	300	WP_008631315.1	nucleotidyltransferase	-
MWM12_RS06515 (TthSNM17_12760)	-	1185616..1185978 (+)	363	WP_060384345.1	HepT-like ribonuclease domain-containing protein	-

Sequence

Protein

• Length: 233 a.a.
• Molecular weight: 24988.49 Da
• Isoelectric Point: 7.4627

>NTDB_id=92986 MWM12_RS06480 WP_244340527.1 1180494..1181195(+) (pilA/pilA3) [Thermus thermophilus strain SNM1-7]
MKRGFTLVEVLVAMAILVVVLAVGVRYFASTSELARNTQARSELQDRVRMVMQVVTADLQMAGARYWNSGNQNRAFSLPL
PPLSGSDMGPKDTLTLYYVTSLRDLASACRRVDYGFEGDTLRRSDVNATPSSGSDCTTPPPNSQPLAEGMLALDIQYQCS
DGSQKDTPDCGTDAYPRSAKVTVAGYSLTPVTNPGPASLTTVTGKTLACPQGRACYALTQEVLMPNLKPLPTP

Nucleotide

• Length: 702 bp

>NTDB_id=92986 MWM12_RS06480 WP_244340527.1 1180494..1181195(+) (pilA/pilA3) [Thermus thermophilus strain SNM1-7]
ATGAAGCGCGGGTTCACCCTGGTGGAAGTCCTGGTGGCCATGGCCATCTTGGTGGTGGTCCTGGCCGTGGGCGTGCGCTA
CTTCGCAAGCACCAGCGAGCTCGCCCGGAACACTCAGGCAAGGAGCGAGCTCCAGGACCGGGTGCGCATGGTGATGCAGG
TGGTGACCGCCGACCTGCAGATGGCGGGGGCCCGCTACTGGAATAGCGGCAACCAAAACCGGGCCTTCAGCCTCCCCCTT
CCCCCGCTTTCGGGAAGCGACATGGGCCCTAAGGACACCCTAACCCTCTACTACGTCACGAGCCTCCGGGACCTGGCCTC
CGCCTGCCGCCGGGTGGACTACGGGTTTGAGGGGGACACCCTACGCCGGAGCGACGTGAACGCCACCCCCTCTTCGGGAA
GCGATTGCACCACCCCCCCTCCGAACTCGCAGCCCTTGGCCGAAGGGATGCTGGCCCTGGACATCCAATACCAGTGCAGC
GACGGAAGCCAGAAGGACACCCCCGACTGCGGTACAGACGCCTACCCCCGCTCGGCCAAGGTCACGGTGGCGGGCTACTC
CCTGACCCCGGTGACCAACCCGGGCCCCGCCTCCCTCACCACCGTCACCGGAAAGACCCTCGCCTGCCCCCAGGGCCGGG
CCTGCTACGCCCTCACCCAGGAGGTCCTCATGCCCAACCTCAAGCCCCTGCCCACCCCCTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (2-23)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA/pilA3	Thermus thermophilus HB27	98.283	100	0.983