Detailed information NTG0928218

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: VXJ35_RS18940
• Genome accession: NZ_CP143089
• Coordinates: 4134256..4135596 (-)
• Length: 446 a.a.
• NCBI ID: WP_054763602.1
• Uniprot ID: A0A172UC47
• Organism: Methylomonas sp. DH-1 strain CS40
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 4129256..4140596

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VXJ35_RS18925	-	4130703..4131554 (-)	852	WP_054762725.1	HDOD domain-containing protein	-
VXJ35_RS18930	-	4131735..4133570 (+)	1836	WP_064022751.1	EAL domain-containing protein	-
VXJ35_RS18935	-	4133722..4134210 (+)	489	WP_064022752.1	hypothetical protein	-
VXJ35_RS18940	pilR	4134256..4135596 (-)	1341	WP_054763602.1	sigma-54 dependent transcriptional regulator	Regulator
VXJ35_RS18945	-	4135593..4137134 (-)	1542	WP_082881000.1	PAS domain-containing sensor histidine kinase	-
VXJ35_RS18950	sucC	4137314..4138483 (+)	1170	WP_064022754.1	ADP-forming succinate--CoA ligase subunit beta	-
VXJ35_RS18955	sucD	4138483..4139355 (+)	873	WP_064022755.1	succinate--CoA ligase subunit alpha	-

Sequence

Protein

• Length: 446 a.a.
• Molecular weight: 49534.08 Da
• Isoelectric Point: 6.2593

>NTDB_id=928218 VXJ35_RS18940 WP_054763602.1 4134256..4135596(-) (pilR) [Methylomonas sp. DH-1 strain CS40]
MNMPVTLVVDDEPDIRELLEITLNRMQIQTRSAATLAEAKHCLANQSFDLCLTDMRLPDGDGLELVDYIQAQGLTLPVAV
ITAHGSMDIAIKAMKKGAFDFLSKPVDLAVLRQLVSHALQISLNRVAEKERRTRDLLLGESAPMRNIRSKIDKVARNQAP
VYISGESGSGKELVARLIHQQSPRSEKAFIAINCGAIPHELMESEFFGHKKGSFTGAVSDKQGLFQAADGGTLFLDEVAD
LPLALQVKLLRAIQEKKIRPIGEQREIPVDVRLLSATHRDLAKMVQEGSFRQDLYYRINVIELNLPPLRARAADIPQLTE
HLLQGLARANGIAIPRLSDAALNALKQYYFPGNVRELENILERALALHEGGVIEVDDLNLPTGLDLAAAEDFDAEKMSLE
SYLEDIEKKALSSALEENRWNKTATAKYLGMSFRSLRYRLKKLGLE

Nucleotide

• Length: 1341 bp

>NTDB_id=928218 VXJ35_RS18940 WP_054763602.1 4134256..4135596(-) (pilR) [Methylomonas sp. DH-1 strain CS40]
ATGAATATGCCTGTTACGTTAGTGGTCGACGACGAACCCGATATTCGGGAACTGTTGGAAATCACGTTAAACCGGATGCA
GATCCAGACCCGTAGCGCGGCTACGTTAGCCGAAGCCAAGCACTGTCTGGCTAACCAATCCTTCGATTTATGCTTGACCG
ACATGCGCTTGCCGGACGGAGACGGCTTGGAACTGGTCGATTACATCCAGGCCCAAGGTTTGACACTGCCGGTGGCGGTA
ATCACCGCCCATGGCAGCATGGATATCGCGATCAAGGCCATGAAAAAAGGCGCGTTCGATTTTCTGTCCAAGCCGGTCGA
TCTGGCGGTGTTAAGGCAATTGGTCAGCCATGCCTTGCAGATCTCGCTGAACCGGGTGGCCGAAAAGGAACGCCGCACCC
GCGATTTGTTGCTCGGGGAATCGGCGCCGATGCGCAATATCCGCTCCAAGATCGATAAAGTGGCGCGCAACCAGGCGCCG
GTTTACATCAGCGGCGAGTCGGGTTCCGGCAAGGAATTGGTGGCGCGGCTGATCCACCAGCAAAGCCCGCGCAGCGAAAA
GGCTTTTATCGCCATCAATTGCGGCGCGATTCCGCACGAATTGATGGAAAGCGAATTTTTCGGCCACAAAAAAGGCAGCT
TCACCGGGGCGGTCAGCGATAAGCAAGGTTTGTTTCAAGCCGCGGACGGCGGCACGCTGTTTCTGGACGAAGTGGCAGAT
TTGCCGTTGGCTTTGCAAGTCAAATTGCTGCGGGCGATACAGGAAAAGAAAATCCGTCCGATCGGCGAGCAGCGCGAAAT
TCCGGTGGACGTGCGTTTGCTGAGCGCAACCCACAGGGATTTGGCCAAAATGGTTCAGGAAGGCAGTTTTCGGCAGGACT
TGTATTACCGGATCAACGTCATCGAATTGAATCTGCCGCCATTACGGGCGCGAGCCGCCGATATTCCGCAATTGACCGAA
CATCTGCTGCAAGGTTTGGCGCGGGCCAACGGTATTGCTATCCCGCGCCTGTCGGATGCGGCGTTGAATGCGCTGAAACA
GTATTATTTTCCGGGCAACGTCCGCGAGTTGGAAAATATTTTGGAGCGGGCTTTGGCGCTGCACGAGGGCGGCGTGATCG
AGGTCGACGATTTGAATTTGCCGACGGGTTTGGACTTGGCCGCGGCGGAAGATTTCGATGCCGAAAAAATGTCGCTGGAA
AGTTATCTGGAAGATATCGAGAAAAAAGCGCTGAGTTCGGCTTTGGAGGAAAACCGCTGGAATAAAACCGCGACGGCTAA
ATATTTGGGCATGAGTTTCCGCTCGTTGCGTTACCGGTTGAAGAAACTCGGTCTGGAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory protein, Fis family (HTH_8) (403-443)

• Sigma-54 interaction domain (Sigma54_activat) (138-303)

• Response regulator receiver domain (Response_reg) (7-115)

3D structure

• AlphaFold DB: A0A172UC47

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	63.333	100	0.639
pilR	Acinetobacter baumannii strain A118	50.644	100	0.529
luxO	Vibrio cholerae strain A1552	39.189	99.552	0.39