Detailed information NTG0926070

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: VVB72_RS05625
• Genome accession: NZ_CP142589
• Coordinates: 1103040..1104362 (-)
• Length: 440 a.a.
• NCBI ID: WP_039115354.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain C20
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1098040..1109362

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VVB72_RS05595 (VVB72_05595)	-	1099183..1100151 (+)	969	WP_003130649.1	PhoH family protein	-
VVB72_RS05600 (VVB72_05600)	-	1100209..1100688 (+)	480	WP_039115350.1	NUDIX hydrolase	-
VVB72_RS05605 (VVB72_05605)	ybeY	1100840..1101328 (+)	489	WP_021722516.1	rRNA maturation RNase YbeY	-
VVB72_RS05610 (VVB72_05610)	-	1101312..1101767 (+)	456	WP_003130653.1	diacylglycerol kinase family protein	-
VVB72_RS05615 (VVB72_05615)	-	1101781..1102359 (+)	579	WP_021722515.1	nucleotidyltransferase family protein	-
VVB72_RS05620 (VVB72_05620)	comFC	1102393..1102797 (-)	405	WP_230593148.1	ComF family protein	Machinery gene
VVB72_RS05625 (VVB72_05625)	comFA	1103040..1104362 (-)	1323	WP_039115354.1	DEAD/DEAH box helicase	Machinery gene
VVB72_RS05630 (VVB72_05630)	-	1104419..1105048 (+)	630	WP_003130660.1	YigZ family protein	-
VVB72_RS05635 (VVB72_05635)	-	1105182..1105679 (+)	498	WP_003130662.1	VanZ family protein	-
VVB72_RS05640 (VVB72_05640)	-	1105727..1106746 (+)	1020	WP_012897709.1	DUF475 domain-containing protein	-
VVB72_RS05645 (VVB72_05645)	-	1106861..1107607 (+)	747	WP_023189339.1	bifunctional metallophosphatase/5'-nucleotidase	-
VVB72_RS05650 (VVB72_05650)	glyQ	1107893..1108846 (+)	954	WP_003130667.1	glycine--tRNA ligase subunit alpha	-

Sequence

Protein

• Length: 440 a.a.
• Molecular weight: 50088.55 Da
• Isoelectric Point: 10.1065

>NTDB_id=926070 VVB72_RS05625 WP_039115354.1 1103040..1104362(-) (comFA) [Lactococcus lactis subsp. lactis strain C20]
MSTNQEKLFGRLLLKNDILQLIKSTDKISVSKIFSNFLLEAKVNPILGMTSISSNKIKCNRCGTVHIKNSVKLPIGVFYC
PSCIQLGRVRSDEFLYFLPQKNFPKKSYINWSGKLTENQKSISNALCQEINSHQQIIVQAVTGAGKTEMIYQVIEQILES
GGVVGLASPRIDVCLELHQRLSRDFSCKIPLLYHDGDSYFRAPLIIMTSHQLLRLKEAFDLLIIDEVDAFSFRDNEMLYF
AAEKARKIEGNLIYLTATSTDKLEKDIKKQKLYPLFLPRRFHNFPLVVPKFFWKNKFDKKLIEQRNSGFPLLIFAAEIES
GQEFAKQLQLKFPKEKIASVASTTKDRLEIVKAFRNKEITILIATSILERGVTFPNVDVFVINSEHPNFTKSALIQMAGR
VGRSPERPTGLVSFFHYGKSKAMCQAVREIKKMNQLGGFS

Nucleotide

• Length: 1323 bp

>NTDB_id=926070 VVB72_RS05625 WP_039115354.1 1103040..1104362(-) (comFA) [Lactococcus lactis subsp. lactis strain C20]
ATGAGCACTAATCAAGAAAAGTTATTTGGCCGTTTATTATTAAAAAATGATATTTTACAACTTATAAAAAGTACTGACAA
GATTTCTGTCAGTAAAATTTTTAGTAATTTTTTGTTAGAAGCGAAGGTGAATCCAATTTTGGGAATGACTTCAATTTCTT
CCAATAAAATAAAATGCAACCGTTGTGGGACTGTTCATATAAAAAATTCTGTCAAACTTCCAATTGGTGTATTTTACTGT
CCAAGTTGTATTCAATTAGGTCGAGTCCGCTCCGATGAATTCTTGTACTTTCTGCCACAAAAGAATTTCCCAAAGAAATC
ATATATAAACTGGTCGGGAAAACTGACAGAGAATCAAAAATCAATTTCAAATGCCCTCTGTCAAGAAATTAATTCTCATC
AGCAAATAATTGTCCAAGCTGTGACTGGAGCTGGAAAAACTGAAATGATTTATCAAGTCATTGAACAAATTTTAGAAAGC
GGTGGAGTTGTTGGTCTAGCTAGTCCAAGAATTGATGTTTGTCTTGAACTTCATCAGCGATTATCACGTGATTTTTCCTG
TAAGATTCCACTCTTATATCATGATGGCGACAGCTATTTCCGAGCTCCATTAATAATAATGACCAGTCATCAGCTTTTAC
GTTTGAAGGAAGCTTTTGATTTGCTGATTATTGATGAAGTTGATGCCTTTTCCTTTAGAGATAATGAAATGCTTTATTTT
GCGGCAGAAAAAGCAAGAAAAATAGAAGGAAATTTAATATATTTGACCGCAACTTCTACTGACAAACTTGAAAAAGATAT
AAAAAAGCAAAAACTCTATCCTTTGTTTCTCCCACGTCGTTTTCACAATTTTCCTTTAGTCGTGCCTAAATTTTTTTGGA
AAAATAAATTTGATAAGAAATTAATTGAGCAAAGAAATAGTGGCTTTCCTCTTCTTATTTTTGCTGCTGAAATTGAATCT
GGACAAGAATTTGCAAAACAACTACAATTGAAATTTCCTAAAGAAAAAATTGCTTCCGTTGCTTCAACAACAAAAGATAG
ATTGGAAATTGTTAAAGCTTTTAGAAATAAAGAAATTACTATTTTAATAGCGACTTCAATTCTTGAACGGGGAGTCACTT
TTCCAAATGTTGATGTTTTTGTCATCAACAGTGAGCACCCAAACTTCACTAAATCCGCACTGATACAAATGGCTGGACGT
GTGGGTCGTAGTCCTGAACGTCCAACAGGCTTAGTTAGTTTTTTTCATTACGGAAAATCCAAAGCAATGTGTCAGGCAGT
TAGAGAAATCAAAAAAATGAACCAACTGGGAGGTTTTTCATGA

Domains

Predicted by InterproScan.

• Helicase conserved C-terminal domain (Helicase_C) (300-403)

• Type III restriction enzyme, res subunit (ResIII) (114-258)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Lactococcus lactis subsp. cremoris KW2	74	90.909	0.673
comFA/cflA	Streptococcus mitis SK321	51.508	90.455	0.466
comFA/cflA	Streptococcus pneumoniae Rx1	51.508	90.455	0.466
comFA/cflA	Streptococcus pneumoniae D39	51.508	90.455	0.466
comFA/cflA	Streptococcus pneumoniae R6	51.508	90.455	0.466
comFA/cflA	Streptococcus pneumoniae TIGR4	51.508	90.455	0.466
comFA/cflA	Streptococcus mitis NCTC 12261	50.754	90.455	0.459
comFA	Bacillus subtilis subsp. subtilis str. 168	37.029	100	0.38