Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EC71350_RS02890 Genome accession   NZ_CP163451
Coordinates   576213..576869 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain M2021-10044802/2-E isolate M2021-10044802/2-E     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 571213..581869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EC71350_RS02860 (EC71350_02860) yecA 572464..573129 (-) 666 WP_000847881.1 UPF0149 family protein YecA -
  EC71350_RS02880 (EC71350_02880) pgsA 573779..574327 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EC71350_RS02885 (EC71350_02885) uvrC 574384..576216 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EC71350_RS02890 (EC71350_02890) letA 576213..576869 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EC71350_RS02895 (EC71350_02895) yecU 577165..577341 (+) 177 WP_000590347.1 protein YecU -
  EC71350_RS02900 (EC71350_02900) yecF 577328..577552 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  EC71350_RS02905 (EC71350_02905) sdiA 577619..578341 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  EC71350_RS02910 (EC71350_02910) tcyN 578571..579323 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EC71350_RS02915 (EC71350_02915) tcyL 579320..579988 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  EC71350_RS02920 (EC71350_02920) dcyD 580003..580989 (-) 987 WP_020232905.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=925985 EC71350_RS02890 WP_000611328.1 576213..576869(-) (letA) [Escherichia coli strain M2021-10044802/2-E isolate M2021-10044802/2-E]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=925985 EC71350_RS02890 WP_000611328.1 576213..576869(-) (letA) [Escherichia coli strain M2021-10044802/2-E isolate M2021-10044802/2-E]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482