Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   VKP54_RS00785 Genome accession   NZ_CP142356
Coordinates   118408..118842 (+) Length   144 a.a.
NCBI ID   WP_111711329.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain CT95-157     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 113408..123842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP54_RS00755 (VKP54_00755) - 115077..115442 (+) 366 WP_002986560.1 DUF1033 family protein -
  VKP54_RS00760 (VKP54_00760) comYA 115535..116473 (+) 939 WP_023612548.1 competence type IV pilus ATPase ComGA Machinery gene
  VKP54_RS00765 (VKP54_00765) comYB 116409..117443 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  VKP54_RS00770 (VKP54_00770) comYC 117445..117771 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  VKP54_RS00775 (VKP54_00775) comGD 117746..118174 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  VKP54_RS00780 (VKP54_00780) comGE 118131..118415 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  VKP54_RS00785 (VKP54_00785) comYF 118408..118842 (+) 435 WP_111711329.1 competence type IV pilus minor pilin ComGF Machinery gene
  VKP54_RS00790 (VKP54_00790) comGG 118826..119152 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  VKP54_RS00795 (VKP54_00795) comYH 119250..120203 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  VKP54_RS00800 (VKP54_00800) - 120262..121458 (+) 1197 WP_111711330.1 acetate kinase -
  VKP54_RS00805 (VKP54_00805) - 121645..121953 (+) 309 WP_011284425.1 hypothetical protein -
  VKP54_RS00810 (VKP54_00810) proC 122036..122806 (-) 771 WP_011284426.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16626.22 Da        Isoelectric Point: 10.1406

>NTDB_id=925303 VKP54_RS00785 WP_111711329.1 118408..118842(+) (comYF) [Streptococcus pyogenes strain CT95-157]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLAHHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide


Download         Length: 435 bp        

>NTDB_id=925303 VKP54_RS00785 WP_111711329.1 118408..118842(+) (comYF) [Streptococcus pyogenes strain CT95-157]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTCCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTACCTAGCCCATCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(42-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

51.079

96.528

0.493
  comYF Streptococcus mutans UA159

50.36

96.528

0.486
  comGF Lactococcus lactis subsp. cremoris KW2

46.715

95.139

0.444
  comGF/cglF Streptococcus mitis NCTC 12261

44.776

93.056

0.417
  comGF/cglF Streptococcus pneumoniae Rx1

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae D39

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae R6

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae TIGR4

43.609

92.361

0.403
  comGF/cglF Streptococcus mitis SK321

42.857

92.361

0.396