Detailed information NTG0925283

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: VKP40_RS06910
• Genome accession: NZ_CP142355
• Coordinates: 1375528..1376880 (-)
• Length: 450 a.a.
• NCBI ID: WP_002985643.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain A946
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1370528..1381880

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP40_RS06900 (VKP40_06900)	rnc	1373580..1374272 (-)	693	WP_002985639.1	ribonuclease III	-
VKP40_RS06905 (VKP40_06905)	vicX	1374715..1375524 (-)	810	WP_002985641.1	MBL fold metallo-hydrolase	Regulator
VKP40_RS06910 (VKP40_06910)	vicK	1375528..1376880 (-)	1353	WP_002985643.1	cell wall metabolism sensor histidine kinase VicK	Regulator
VKP40_RS06915 (VKP40_06915)	vicR	1376873..1377583 (-)	711	WP_002985645.1	response regulator YycF	Regulator
VKP40_RS06920 (VKP40_06920)	-	1377745..1378779 (-)	1035	WP_011284595.1	DUF3114 domain-containing protein	-
VKP40_RS06925 (VKP40_06925)	-	1378835..1380082 (-)	1248	WP_032464244.1	AMP-binding protein	-
VKP40_RS06930 (VKP40_06930)	-	1380039..1381187 (-)	1149	WP_032464243.1	acetyl-CoA C-acyltransferase	-
VKP40_RS06935 (VKP40_06935)	-	1381156..1381725 (-)	570	WP_063629690.1	hypothetical protein	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51439.91 Da
• Isoelectric Point: 5.5556

>NTDB_id=925283 VKP40_RS06910 WP_002985643.1 1375528..1376880(-) (vicK) [Streptococcus pyogenes strain A946]
MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMMSHKIRYLINGRYTDIIDEKADIELMELSDQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWIEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD

Nucleotide

• Length: 1353 bp

>NTDB_id=925283 VKP40_RS06910 WP_002985643.1 1375528..1376880(-) (vicK) [Streptococcus pyogenes strain A946]
ATGACTAGAGATATCATTGGAAACTTATCCACATTTGAATTAGCGATCCTTATCTTACTTGTTTTTGTTGCTTTTTACTT
TATCCATCTTGCGGTGCGTGATTACCGAAATGCACGTATTATTCGGATGATGAGCCATAAAATCCGATACTTGATTAATG
GTCGCTATACTGATATAATCGACGAAAAAGCAGACATTGAGTTAATGGAGCTTTCAGACCAGTTAAATGACCTGTCAGAT
GTTTTTCGCTTGACGCATGAAAATCTTGCCCAAGAAAAAAATCGCTTGGCAAGTATTTTGGCTTATATGTCAGATGGTGT
ACTTGCTACAGACCGGTCTGGTAAAATCATCATGATTAACGAAACAGCTCGCAAGCAATTAAATTTAAGTAAAGAAGAGG
CACTAAAGAAAAACATTACAGATTTGTTAGAAGGTGATACTTCATATACCTACCGTGATTTGGTATCCAAAACACCAGTG
GTAACTGTTAATAGCCGAAATGATATGGGTGAGTTTGTCTCATTACGCTTGCGCTTTGCGTTGAATAGGAGAGAGAGTGG
TTTTATTTCGGGCTTGGTTGTGGTGCTCCATGACACCACAGAACAAGAAAAAGAAGAACGTGAACGCCGTCTTTTTGTCT
CTAATGTAAGTCATGAATTAAGGACCCCTTTAACTTCGGTTAAATCCTACTTGGAGGCTCTTGATGAAGGTGCACTTAAA
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCAGATCTTTTAAA
CCTGTCTCGGATTGATAATCAAGTAACCCAATTAGCAGTAGAGATGACTAATTTTACTGCTTTTATAACTTCTATTTTAA
ACAGATTTGATTTGGTTAAAAATCAGCATACAGGTACAGGAAAAGTCTATGAAATTGTAAGAGATTACCCTATTACCTCT
GTCTGGATTGAAATTGATAATGATAAAATGACACAGGTTATCGAGAATATTTTGAACAATGCCATTAAGTATTCTCCAGA
TGGTGGAAAAATCACAGTCCGTATGAAAACAACAGATACCCAATTAATTATTTCCATTTCAGACCAAGGACTAGGTATCC
CTAAAACAGATTTGCCTCTTATTTTTGATCGGTTCTATCGTGTAGACAAGGCAAGAAGTCGTGCCCAAGGAGGGACCGGT
CTAGGCCTTGCCATTGCTAAAGAAATCATCAAGCAGCACCATGGCTTTATCTGGGCTAAGAGTGACTATGGTAAAGGATC
GACCTTTACTATTGTCTTGCCTTATGAAAAAGATGCAGCCATCTATGAAGAATGGGAGGAAGATGTAGACTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• PAS fold (PAS) (95-162)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	72.947	92	0.671
micB	Streptococcus pneumoniae Cp1015	67.529	94.444	0.638