Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   VKP53_RS01555 Genome accession   NZ_CP142354
Coordinates   286963..288033 (+) Length   356 a.a.
NCBI ID   WP_010921893.1    Uniprot ID   A0A4U9C068
Organism   Streptococcus pyogenes strain 6745-99     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 281963..293033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VKP53_RS01540 (VKP53_01540) amiA 282491..284461 (+) 1971 WP_326674895.1 peptide ABC transporter substrate-binding protein Regulator
  VKP53_RS01545 (VKP53_01545) amiC 284526..286028 (+) 1503 WP_326674898.1 ABC transporter permease Regulator
  VKP53_RS01550 (VKP53_01550) amiD 286028..286954 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  VKP53_RS01555 (VKP53_01555) amiE 286963..288033 (+) 1071 WP_010921893.1 ABC transporter ATP-binding protein Regulator
  VKP53_RS01560 (VKP53_01560) amiF 288026..288949 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  VKP53_RS09035 - 288987..289070 (-) 84 Protein_263 IS3 family transposase -
  VKP53_RS09040 - 289199..289507 (-) 309 Protein_264 IS3 family transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39703.77 Da        Isoelectric Point: 5.6707

>NTDB_id=925204 VKP53_RS01555 WP_010921893.1 286963..288033(+) (amiE) [Streptococcus pyogenes strain 6745-99]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=925204 VKP53_RS01555 WP_010921893.1 286963..288033(+) (amiE) [Streptococcus pyogenes strain 6745-99]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9C068

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537