Detailed information NTG0924955

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: VKP35_RS07375
• Genome accession: NZ_CP142349
• Coordinates: 1427286..1428287 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain 11RS100
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1422286..1433287

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VKP35_RS07360 (VKP35_07360)	thrS	1422456..1424399 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
VKP35_RS07365 (VKP35_07365)	-	1424821..1426155 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
VKP35_RS07370 (VKP35_07370)	-	1426157..1427155 (-)	999	WP_326622621.1	glycosyltransferase family 4 protein	-
VKP35_RS07375 (VKP35_07375)	ccpA	1427286..1428287 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
VKP35_RS07380 (VKP35_07380)	-	1428461..1429546 (+)	1086	WP_002985682.1	aminopeptidase P family protein	-
VKP35_RS07385 (VKP35_07385)	-	1429595..1430260 (+)	666	WP_326622623.1	NAD(P)H-dependent oxidoreductase	-
VKP35_RS07390 (VKP35_07390)	-	1430271..1430648 (+)	378	WP_002985686.1	VOC family protein	-
VKP35_RS07395 (VKP35_07395)	-	1430793..1431719 (+)	927	WP_002985688.1	glycosyltransferase family 2 protein	-
VKP35_RS07400 (VKP35_07400)	-	1431930..1432613 (+)	684	WP_002990714.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=924955 VKP35_RS07375 WP_002985680.1 1427286..1428287(-) (ccpA) [Streptococcus pyogenes strain 11RS100]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=924955 VKP35_RS07375 WP_002985680.1 1427286..1428287(-) (ccpA) [Streptococcus pyogenes strain 11RS100]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGAGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559