Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   VQ623_RS04695 Genome accession   NZ_CP142094
Coordinates   942684..943313 (+) Length   209 a.a.
NCBI ID   WP_037551137.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain MLK17     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 937684..948313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VQ623_RS04670 (VQ623_04670) - 938394..939251 (-) 858 Protein_914 SDR family oxidoreductase -
  VQ623_RS04675 (VQ623_04675) - 939320..940327 (-) 1008 WP_053019077.1 HoxN/HupN/NixA family nickel/cobalt transporter -
  VQ623_RS04680 (VQ623_04680) - 940539..940925 (+) 387 WP_037537962.1 hypothetical protein -
  VQ623_RS04685 (VQ623_04685) liaF 940950..941651 (+) 702 WP_011275374.1 cell wall-active antibiotics response protein LiaF -
  VQ623_RS04690 (VQ623_04690) vraS 941648..942694 (+) 1047 WP_037537960.1 sensor histidine kinase Regulator
  VQ623_RS04695 (VQ623_04695) vraR 942684..943313 (+) 630 WP_037551137.1 two-component system response regulator VraR Regulator
  VQ623_RS04700 (VQ623_04700) - 943376..944587 (-) 1212 WP_107612160.1 YihY/virulence factor BrkB family protein -
  VQ623_RS04705 (VQ623_04705) - 944788..945072 (-) 285 WP_011275378.1 YtxH domain-containing protein -
  VQ623_RS04710 (VQ623_04710) - 945078..945542 (-) 465 WP_037537954.1 low molecular weight protein-tyrosine-phosphatase -
  VQ623_RS04715 (VQ623_04715) - 945684..945893 (+) 210 WP_080290985.1 DUF1128 domain-containing protein -
  VQ623_RS04720 (VQ623_04720) - 945907..947154 (+) 1248 WP_107612159.1 aminopeptidase -
  VQ623_RS04725 (VQ623_04725) - 947187..947720 (+) 534 WP_326008356.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23591.23 Da        Isoelectric Point: 5.0058

>NTDB_id=921459 VQ623_RS04695 WP_037551137.1 942684..943313(+) (vraR) [Staphylococcus haemolyticus strain MLK17]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEIVGEGESGKDAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIADAVRKTYNGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=921459 VQ623_RS04695 WP_037551137.1 942684..943313(+) (vraR) [Staphylococcus haemolyticus strain MLK17]
ATGACGATTAAAGTTTTGTTCGTTGATGACCATGAAATGGTTAGAATTGGGATATCAAGTTATCTATCAACACAATCTGA
CATTGAGATAGTTGGAGAAGGGGAATCTGGTAAAGACGCCATTGCAAAAGCTCATGAATTAAAACCTGATTTAATTCTTA
TGGATTTATTAATGGATGACATGGATGGTGTCGAAGCAACTACTCAAATCAAAAAAGATTTGCCGCATATTAAAGTTGTA
ATGTTAACTAGTTTTATTGAAGATAAAGAAGTATATAGAGCATTAGATGCTGGTGTAGATAGCTATATTTTAAAAACGAC
TAGTGCTAGTGATATAGCCGACGCAGTACGCAAAACTTATAATGGTGAATCGGTATTTGAACCTGAAGTTTTAGTTAAGA
TGCGTAACAGAATGAAGAAACGTGCAGAATTATATGAAATGCTGACTGAGCGTGAAATGGAAATTTTATTATTAATTGCA
AAAGGGTATTCAAATCAAGAAATAGCGAGTGCTTCTCATATTACAATTAAAACCGTTAAAACTCATGTAAGTAATATATT
GAGTAAATTAGAAGTACAAGATAGAACACAAGCCGTAATTTATGCATTCCAACATAATTTGATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.694

100

0.957
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364