Detailed information NTG0921458

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: VQ623_RS04690
• Genome accession: NZ_CP142094
• Coordinates: 941648..942694 (+)
• Length: 348 a.a.
• NCBI ID: WP_037537960.1
• Uniprot ID: A0AB38PEC5
• Organism: Staphylococcus haemolyticus strain MLK17
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 936648..947694

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VQ623_RS04665 (VQ623_04665)	map	937532..938284 (+)	753	WP_011275369.1	type I methionyl aminopeptidase	-
VQ623_RS04670 (VQ623_04670)	-	938394..939251 (-)	858	Protein_914	SDR family oxidoreductase	-
VQ623_RS04675 (VQ623_04675)	-	939320..940327 (-)	1008	WP_053019077.1	HoxN/HupN/NixA family nickel/cobalt transporter	-
VQ623_RS04680 (VQ623_04680)	-	940539..940925 (+)	387	WP_037537962.1	hypothetical protein	-
VQ623_RS04685 (VQ623_04685)	liaF	940950..941651 (+)	702	WP_011275374.1	cell wall-active antibiotics response protein LiaF	-
VQ623_RS04690 (VQ623_04690)	vraS	941648..942694 (+)	1047	WP_037537960.1	sensor histidine kinase	Regulator
VQ623_RS04695 (VQ623_04695)	vraR	942684..943313 (+)	630	WP_037551137.1	two-component system response regulator VraR	Regulator
VQ623_RS04700 (VQ623_04700)	-	943376..944587 (-)	1212	WP_107612160.1	YihY/virulence factor BrkB family protein	-
VQ623_RS04705 (VQ623_04705)	-	944788..945072 (-)	285	WP_011275378.1	YtxH domain-containing protein	-
VQ623_RS04710 (VQ623_04710)	-	945078..945542 (-)	465	WP_037537954.1	low molecular weight protein-tyrosine-phosphatase	-
VQ623_RS04715 (VQ623_04715)	-	945684..945893 (+)	210	WP_080290985.1	DUF1128 domain-containing protein	-
VQ623_RS04720 (VQ623_04720)	-	945907..947154 (+)	1248	WP_107612159.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40138.53 Da
• Isoelectric Point: 5.8508

>NTDB_id=921458 VQ623_RS04690 WP_037537960.1 941648..942694(+) (vraS) [Staphylococcus haemolyticus strain MLK17]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAYKINQQNQWIKS
QIEHAIEGETVGINDQNIELYNETIDIYQTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMVQESQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVIHDI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGSKVTVELFNQQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDDNNDD

Nucleotide

• Length: 1047 bp

>NTDB_id=921458 VQ623_RS04690 WP_037537960.1 941648..942694(+) (vraS) [Staphylococcus haemolyticus strain MLK17]
ATGAACCACTACTTAAGAGCTATCGGTTCAATGCTTATACTAGTTTATAGCATGTTAACCGCGTTCTTATTTATAGATAA
AGTATTTGTTAATATTATCTATTTCCAAGGTATGTTTTATACTCAAATTTTTGGGATACCTGTTTTTCTATTTTTAAATT
TAGTCATCATTTTACTTTGTATTATAGTAGGTTCAATTCTCGCATATAAAATTAATCAACAAAATCAGTGGATTAAGTCG
CAAATCGAGCATGCCATTGAAGGAGAAACAGTAGGTATTAATGATCAAAACATTGAGCTCTATAACGAAACCATAGATAT
TTATCAAACATTAGTTCCGTTGAATCAAGAGTTACACCGTTTACGAATGAAAACGCAAAACTTAACTAATGAGAATTATA
ATATGAATGATGTTAAAGTTAAGAAAATCATTGAGGATGAACGACAGAGATTAGCTCGCGAGTTACACGACTCTGTTAGT
CAACAACTTTTTGCAGCAAGCATGATGTTATCTGCAATAAAAGAAACAAAATTAGAGGCACCGCTTGATCAACAAATACC
AGTATTAGAGAAAATGGTACAGGAATCTCAACTTGAAATGCGCGCATTGTTACTTCATTTAAGACCTTTAGGACTGAAAG
ATAAATCTCTAGGTGAAGGTATCAAAGATTTAGTTATTGATTTGCAAAAGAAAGTGCCTATGAAAGTCATACACGATATT
CAAGATTTTAAGGTGCCTAAAGGTATAGAAGATCATTTATTTAGAATTACACAAGAGGCTATATCAAATACGTTAAGACA
TTCTAATGGATCTAAAGTTACAGTGGAATTATTTAACCAACAAGATTATCTATTACTTCGAATTCAAGATAATGGTAAAG
GATTCAATGTTGACGAGAAATTAGAACAAAGTTATGGATTAAAAAATATGAGGGAACGCGCATTAGAAATTGGTGCGACA
TTCCATATTGTTTCGTTACCGGATTCTGGAACGAGAATAGAAGTTAAAGCACCGTTAAATAAGGAGGATGATAATAATGA
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.643	99.713	0.914