Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   VFH86_RS04945 Genome accession   NZ_CP142014
Coordinates   1057201..1059444 (+) Length   747 a.a.
NCBI ID   WP_345659016.1    Uniprot ID   -
Organism   Vibrio cholerae strain LK-18     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1052201..1064444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VFH86_RS04920 (VFH86_04920) - 1052664..1053239 (-) 576 WP_111673968.1 PilZ domain-containing protein -
  VFH86_RS04925 (VFH86_04925) lolC 1053415..1054623 (+) 1209 WP_000468891.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  VFH86_RS04930 (VFH86_04930) lolD 1054616..1055302 (+) 687 WP_001061290.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  VFH86_RS04935 (VFH86_04935) lolE 1055303..1056547 (+) 1245 WP_345658741.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  VFH86_RS04940 (VFH86_04940) - 1056662..1057192 (-) 531 WP_001881633.1 DUF2062 domain-containing protein -
  VFH86_RS04945 (VFH86_04945) comEC 1057201..1059444 (+) 2244 WP_345659016.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  VFH86_RS04950 (VFH86_04950) msbA 1059475..1061223 (+) 1749 WP_336915668.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  VFH86_RS04955 (VFH86_04955) lpxK 1061226..1062233 (+) 1008 WP_187371900.1 tetraacyldisaccharide 4'-kinase -
  VFH86_RS04960 (VFH86_04960) - 1062214..1062393 (+) 180 WP_000350068.1 Trm112 family protein -
  VFH86_RS04965 (VFH86_04965) kdsB 1062393..1063151 (+) 759 WP_000011327.1 3-deoxy-manno-octulosonate cytidylyltransferase -

Sequence

Protein


Download         Length: 747 a.a.        Molecular weight: 84443.61 Da        Isoelectric Point: 7.7612

>NTDB_id=920934 VFH86_RS04945 WP_345659016.1 1057201..1059444(+) (comEC) [Vibrio cholerae strain LK-18]
MTLLSNYWSLISFSITVLSAPYWPWMPSWGWAWLCLIVMVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNVLYQAGP
DIIIKGRVDSFFTQTRYAYEGFVLIHEVNGQTLNKMTRPRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYM
AQSVVARAVVKPDTAYQIVQESGIRSSLFFELEQLTHTSPYQGLILALTFGERKGIDEQEWQALRNSGLIHLVAISGLHI
GIAFSVGYFLGLGMMRLHAQLLWSPFVCGALLAVLYAWLAGFTLPTQRALIMCLLNVALIMLAFPLSALKRILLTLVAVL
LWSPFASLSNSFWMSFLAVAIVLYQLASQSQRQVWWKALLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVI
VPALFLGLLLMVVWPSVAAAYWPWVDWTFLPLDWALQFADVGWWVVPSKVQGVVAASVAILLLYRFMSLKACSLLLGMIG
LWWWFPSLTPLWRMDVLDVGHGLAIVIEQDERAIVYDTGSSWPGGSYVQSVIEPILQQRGLRQVDGVILSHLDNDHAGDW
QGLAERWQPNWIRASQLGTEFMPCIRGESWQWQSLHFTVLWPPQAVSRAYNQHSCVIRMTDTQSNHSVLLSGDVTAMGEW
LLARDGAQLQSEVMIVPHHGSKTSSTAEFIAQVNPKLAIASVAKDNRWNLPNPQVVARYQAQQVEWLDTGHAGQISLFFY
PDQLDWFTQRSLGWQPWYRQMLRKGVE

Nucleotide


Download         Length: 2244 bp        

>NTDB_id=920934 VFH86_RS04945 WP_345659016.1 1057201..1059444(+) (comEC) [Vibrio cholerae strain LK-18]
ATGACTCTCTTGTCGAATTACTGGTCTCTCATTTCTTTTTCGATCACCGTGCTGTCTGCCCCTTATTGGCCTTGGATGCC
GAGTTGGGGTTGGGCTTGGTTATGCCTTATTGTTATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCTTGGCT
TCGTGGCTGCCATACTAACCATTGTGCTACAGGGCAACCTTATACGAGATCAATCCAATGTGCTCTATCAAGCAGGGCCG
GATATTATCATAAAAGGCCGTGTTGACAGCTTTTTTACGCAAACTCGTTACGCTTATGAGGGTTTTGTCCTCATTCATGA
AGTGAATGGACAAACCTTAAACAAAATGACTCGCCCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAATGACC
GCGTCGAATTTTCGGTAACTCTCAAGCCGATAGTGGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATTACATG
GCGCAATCTGTCGTCGCACGGGCGGTCGTAAAACCTGACACCGCTTATCAAATTGTGCAAGAGAGTGGCATAAGGTCAAG
TTTGTTTTTTGAGCTGGAACAATTAACGCATACCAGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGAGCGAA
AAGGTATTGATGAGCAAGAGTGGCAAGCCTTACGCAATAGTGGCTTAATTCATTTAGTGGCGATTTCGGGGCTGCACATT
GGTATCGCTTTTAGCGTGGGGTATTTTCTCGGGCTCGGCATGATGCGTCTTCATGCTCAGTTATTGTGGTCCCCTTTTGT
GTGTGGGGCTTTACTGGCGGTGCTCTACGCTTGGCTGGCCGGATTTACGTTGCCTACTCAGCGTGCATTGATCATGTGCT
TACTCAATGTGGCGTTGATCATGTTGGCTTTTCCTCTTTCCGCGCTCAAGCGGATTCTACTCACCTTAGTCGCGGTCTTG
CTTTGGTCGCCATTCGCCTCACTTTCAAACAGTTTCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAATTAGC
CAGTCAAAGCCAGCGTCAGGTGTGGTGGAAAGCTCTGCTTTGGGCGCAGGTGTTCCTCGTCTGTTTAATGGCACCGGTCA
CGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGCAGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGGTGATT
GTCCCAGCTTTGTTTTTGGGCCTACTACTCATGGTGGTATGGCCTAGTGTGGCCGCCGCTTACTGGCCTTGGGTGGATTG
GACGTTTTTACCGCTCGATTGGGCTTTGCAGTTTGCCGATGTAGGCTGGTGGGTGGTACCCAGCAAAGTACAAGGTGTAG
TCGCAGCGAGTGTGGCCATCCTCTTGCTTTATCGATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGATTGGC
TTATGGTGGTGGTTTCCCTCTCTCACTCCACTTTGGCGAATGGATGTGCTGGATGTTGGACATGGCTTGGCGATTGTGAT
TGAGCAAGATGAGCGAGCAATTGTCTACGATACAGGCAGCAGTTGGCCGGGAGGCAGCTATGTGCAAAGCGTGATTGAGC
CTATTCTCCAACAGCGAGGGCTACGCCAAGTCGATGGAGTGATTTTAAGTCATCTTGATAATGATCATGCGGGTGATTGG
CAAGGTTTAGCTGAGCGCTGGCAACCCAATTGGATTCGTGCCAGCCAACTCGGGACAGAGTTTATGCCTTGTATCCGTGG
TGAAAGCTGGCAGTGGCAATCTCTCCATTTTACGGTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCAGCATT
CGTGTGTGATTCGTATGACCGATACTCAGTCTAACCATTCTGTACTGCTCTCCGGGGATGTCACAGCCATGGGGGAGTGG
CTGCTTGCTCGCGACGGAGCGCAACTGCAAAGTGAGGTGATGATCGTGCCGCATCACGGCAGTAAAACGTCGTCCACCGC
AGAGTTTATAGCACAAGTGAATCCCAAACTTGCGATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAATCCGC
AAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGAGTGGCTAGATACTGGACACGCTGGGCAAATTAGCCTCTTTTTCTAT
CCAGATCAGCTGGATTGGTTTACCCAGCGTAGTCTTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGAGTAGA
ATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(21-173)

Competence protein (Competence)

(208-464)

Metallo-beta-lactamase superfamily (Lactamase_B)

(499-679)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

99.598

100

0.996
  comEC Vibrio parahaemolyticus RIMD 2210633

41.347

100

0.419
  comEC Vibrio campbellii strain DS40M4

41.09

100

0.414