Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AB3N51_RS18370 Genome accession   NZ_CP162190
Coordinates   3774924..3775514 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain STK77-E     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3769924..3780514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3N51_RS18355 (AB3N51_18355) uhpT 3770564..3771955 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  AB3N51_RS18360 (AB3N51_18360) uhpC 3772093..3773412 (-) 1320 WP_001358267.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  AB3N51_RS18365 (AB3N51_18365) uhpB 3773422..3774924 (-) 1503 WP_001330988.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  AB3N51_RS18370 (AB3N51_18370) letA 3774924..3775514 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  AB3N51_RS18375 (AB3N51_18375) ilvN 3775589..3775879 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  AB3N51_RS18380 (AB3N51_18380) ilvB 3775883..3777571 (-) 1689 WP_023140520.1 acetolactate synthase large subunit -
  AB3N51_RS18385 (AB3N51_18385) ivbL 3777677..3777775 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  AB3N51_RS18390 (AB3N51_18390) tisB 3778340..3778429 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  AB3N51_RS18395 (AB3N51_18395) ysdE 3778692..3778766 (-) 75 WP_211180519.1 protein YsdE -
  AB3N51_RS18400 (AB3N51_18400) emrD 3778848..3780032 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=920600 AB3N51_RS18370 WP_000633668.1 3774924..3775514(-) (letA) [Escherichia coli strain STK77-E]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=920600 AB3N51_RS18370 WP_000633668.1 3774924..3775514(-) (letA) [Escherichia coli strain STK77-E]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378